PDB: 17079 resultsInfo pagesStatus searchChemie searchBIRD

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4YL8	Crystal structure of the Crumbs/Moesin complex Descriptor: GLYCEROL, IODIDE ION, Moesin, ... Authors: Wei, Z, Li, Y, Zhang, M. Deposit date: 2015-03-05 Release date: 2015-04-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural Basis for the Phosphorylation-regulated Interaction between the Cytoplasmic Tail of Cell Polarity Protein Crumbs and the Actin-binding Protein Moesin J.Biol.Chem., 290, 2015
8ZMD	Protease-activated receptor-2 (PAR2)/Gq complex Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Proteinase-activated receptor 2, ... Authors: He, Y, Zhu, X. Deposit date: 2024-05-23 Release date: 2025-05-28 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: Protease-activated receptor-2 (PAR2)/Gq complex To Be Published
4YLQ	Crystal Structure of a FVIIa-Trypsin Chimera (FT) in Complex with Soluble Tissue Factor Descriptor: CALCIUM ION, Coagulation factor VII, N-PROPANOL, ... Authors: Sorensen, A.B, Svensson, L.A, Gandhi, P.S. Deposit date: 2015-03-05 Release date: 2015-12-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity. J.Biol.Chem., 291, 2016
8ZGR	80S ribosome with A/A tRNA and mRNA of WNV Descriptor: 25S rRNA (3393-MER), 5.8S rRNA (158-MER), 5S rRNA (121-MER), ... Authors: Wu, M, Yuan, S. Deposit date: 2024-05-09 Release date: 2025-05-21 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Flexibilities and conservations in the structural basis of viral -1 programmed ribosomal frameshifting To Be Published
8ZVZ	Cryo-EM strcuture of Prostaglandin D2 Receptor DP1 activated by BW245C Descriptor: 7-{(4S)-3-[(3R)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxoimidazolidin-4-yl}heptanoic acid, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Xu, J, Xu, Y, Wu, C, Xu, H.E. Deposit date: 2024-06-12 Release date: 2025-05-28 Last modified: 2025-06-25 Method: ELECTRON MICROSCOPY (2.35 Å) Cite: Molecular basis for ligand recognition and receptor activation of the prostaglandin D2 receptor DP1. Proc.Natl.Acad.Sci.USA, 122, 2025
1GUZ	Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases Descriptor: MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Dalhus, B, Sarinen, M, Sauer, U.H, Eklund, P, Johansson, K, Karlsson, A, Ramaswamy, S, Bjork, A, Synstad, B, Naterstad, K, Sirevag, R, Eklund, H. Deposit date: 2002-02-04 Release date: 2002-02-21 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases J.Mol.Biol., 318, 2002
8Z68	Cryo-EM structure of the hGPR68-Gs complex in pH6.8 Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... Authors: Zhong, Y.N, Guo, L.L, Yang, F, Sun, J.P. Deposit date: 2024-04-18 Release date: 2025-04-23 Method: ELECTRON MICROSCOPY (2.64 Å) Cite: Cryo-EM structure of the hGPR68-Gs complex in pH6.8 To Be Published
7WRI	Cryo-EM structure of SARS-CoV-2 Omicron spike receptor-binding domain in complex with mouse ACE2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein, ... Authors: Han, P, Xie, Y, Qi, J. Deposit date: 2022-01-26 Release date: 2022-06-08 Last modified: 2025-06-25 Method: ELECTRON MICROSCOPY (3.03 Å) Cite: Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s. Cell Discov, 8, 2022
8Z65	Cryo-EM structure of the hGPR4-Gs complex in pH7.2 Descriptor: G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Zhong, Y.N, Guo, L.L. Deposit date: 2024-04-18 Release date: 2025-04-23 Method: ELECTRON MICROSCOPY (2.97 Å) Cite: Cryo-EM structure of the hGPR4-Gs complex in pH7.2 To Be Published
8Z3Q	Cryo-EM structure of the hGPR4-Gs complex in pH7.6 Descriptor: G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Zhong, Y.N, Guo, L.L, Yang, F, Sun, J.P. Deposit date: 2024-04-15 Release date: 2025-04-23 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: Cryo-EM structure of the hGPR4-Gs complex in pH7.6 To Be Published
6YWV	The structure of the Atp25 bound assembly intermediate of the mitoribosome from Neurospora crassa Descriptor: 23 S rRNA, 50S ribosomal protein L14, 50S ribosomal protein L17, ... Authors: Amunts, A, Itoh, Y, Naschberger, A. Deposit date: 2020-04-30 Release date: 2020-11-11 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.03 Å) Cite: Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
7X2F	Cryo-EM structure of the dopamine and LY3154207-bound D1 dopamine receptor and mini-Gs complex Descriptor: 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ... Authors: Teng, X, Zheng, S. Deposit date: 2022-02-25 Release date: 2022-06-15 Last modified: 2025-06-18 Method: ELECTRON MICROSCOPY (3 Å) Cite: Ligand recognition and biased agonism of the D1 dopamine receptor. Nat Commun, 13, 2022
8YYX	Cryo-EM structure of OXGR1 bound to leukotriene E4 and Gq proteins Descriptor: (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-azanyl-3-oxidanyl-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid, 2-oxoglutarate receptor 1, CHOLESTEROL, ... Authors: Liu, A, Liu, Y. Deposit date: 2024-04-04 Release date: 2025-04-09 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (2.84 Å) Cite: Cryo-EM structure of OXGR1 bound to leukotriene E4 and Gq proteins To Be Published
7WV9	Allosteric modulator ZCZ011 binding to CP55940-bound cannabinoid receptor 1 in complex with Gi protein Descriptor: 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 6-methyl-3-[(1S)-2-nitro-1-thiophen-2-yl-ethyl]-2-phenyl-1H-indole, Cannabinoid receptor 1, ... Authors: Xu, Z, Shao, Z. Deposit date: 2022-02-10 Release date: 2022-06-15 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (3.36 Å) Cite: Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1. Nat.Chem.Biol., 18, 2022
7X2D	Cryo-EM structure of the tavapadon-bound D1 dopamine receptor and mini-Gs complex Descriptor: 1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxy-phenyl]pyrimidine-2,4-dione, CHOLESTEROL, D(1A) dopamine receptor, ... Authors: Teng, X, Zheng, S. Deposit date: 2022-02-25 Release date: 2022-06-15 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Ligand recognition and biased agonism of the D1 dopamine receptor. Nat Commun, 13, 2022
8QTQ	Thermostable WW domain Descriptor: WW domain Authors: Kovermann, M, Thomas, F. Deposit date: 2023-10-13 Release date: 2024-07-03 Method: SOLUTION NMR Cite: Thermostable WW-Domain Scaffold to Design Functional beta-Sheet Miniproteins. J.Am.Chem.Soc., 2024
8Z5H	Cryo-EM structure of the hGPR68-Gs complex in pH6.0 Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... Authors: Zhong, Y.N, Guo, L.L, Yang, F, Sun, J.P. Deposit date: 2024-04-18 Release date: 2025-04-23 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Cryo-EM structure of the hGPR68-Gs complex in pH6.0 To Be Published
6ZJD	Crystal structure of human adenylate kinase 3, AK3, in complex with inhibitor ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GTP:AMP phosphotransferase AK3, ... Authors: Grundstrom, C, Rogne, P, Wolf-Watz, M, Sauer-Eriksson, A.E. Deposit date: 2020-06-28 Release date: 2020-09-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3. Biochemistry, 59, 2020
7WKD	TRH-TRHR G protein complex Descriptor: Gq, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Xu, Y, Cai, H, You, C, He, X, Yuan, Q, Jiang, H, Cheng, X, Jiang, Y, Xu, H.E. Deposit date: 2022-01-09 Release date: 2022-06-15 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Structural insights into ligand binding and activation of the human thyrotropin-releasing hormone receptor. Cell Res., 32, 2022
8Z3M	Cryo-EM structure of the hGPR4-Gq complex in pH6.5 Descriptor: Engineered G-alpha-q subunit, G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Zhong, Y.N, Guo, L.L, Yang, F, Sun, J.P. Deposit date: 2024-04-15 Release date: 2025-04-23 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Cryo-EM structure of the hGPR4-Gq complex in pH6.5 To Be Published
6ZCV	Crystal structure of lanthanide-dependent alcohol dehydrogenase PedH from Pseudomonas putida KT2440 Descriptor: CALCIUM ION, GLYCEROL, PRASEODYMIUM ION, ... Authors: Bange, G, Lepak, A, Elsayed, E.M. Deposit date: 2020-06-12 Release date: 2020-07-15 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Engineered PQQ-Dependent Alcohol Dehydrogenase for the Oxidation of 5-(Hydroxymethyl)furoic Acid Acs Catalysis, 2020
7X8R	Cryo-EM structure of the Boc5-bound hGLP-1R-Gs complex Descriptor: 2,4-bis(3-methoxy-4-thiophen-2-ylcarbonyloxy-phenyl)-1,3-bis[[4-[(2-methylpropan-2-yl)oxycarbonylamino]phenyl]carbonylamino]cyclobutane-1,3-dicarboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Cong, Z.T, Zhou, Q.T, Li, Y, Chen, L.N, Zhang, Z.C, Liang, A.Y, Liu, Q, Wu, X.Y, Dai, A.T, Xia, T, Wu, W, Zhang, Y, Yang, D.H, Wang, M.W. Deposit date: 2022-03-14 Release date: 2022-06-29 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (2.61 Å) Cite: Structural basis of peptidomimetic agonism revealed by small- molecule GLP-1R agonists Boc5 and WB4-24. Proc.Natl.Acad.Sci.USA, 119, 2022
8BHL	Elongating E. coli 70S ribosome containing acylated tRNA(iMet) in the P-site and Am6AA mRNA codon in the A-site after uncompleted di-peptide formation Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ... Authors: Koziej, L, Glatt, S. Deposit date: 2022-10-31 Release date: 2023-08-16 Method: ELECTRON MICROSCOPY (2.21 Å) Cite: Modulation of translational decoding by m 6 A modification of mRNA. Nat Commun, 14, 2023
8BH4	Elongating E. coli 70S ribosome containing deacylated tRNA(iMet) in the P-site and AAm6A mRNA codon with cognate dipeptidyl-tRNA(Lys) in the A-site Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ... Authors: Koziej, L, Glatt, S. Deposit date: 2022-10-29 Release date: 2023-08-16 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (2.62 Å) Cite: Modulation of translational decoding by m 6 A modification of mRNA. Nat Commun, 14, 2023
6ZJB	Crystal structure of human adenylate kinase 3, AK3, in complex with inhibitor Gp5A Descriptor: GTP:AMP phosphotransferase AK3, mitochondrial, MAGNESIUM ION, ... Authors: Grundstrom, C, Rogne, P, Wolf-Watz, M, Sauer-Eriksson, A.E. Deposit date: 2020-06-28 Release date: 2020-09-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.822 Å) Cite: Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3. Biochemistry, 59, 2020

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