7YVP
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH272/281 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH272 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVO
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH027/132 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH132 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVN
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH281 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH281 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVM
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH272 Fab | Descriptor: | Spike glycoprotein, TH281 Fab heavy chain, TH281 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVL
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH272 Fab | Descriptor: | Spike glycoprotein, TH272 Fab heavy chain, TH272 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVK
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH272 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH272 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVJ
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH236 Fab | Descriptor: | Spike glycoprotein, TH236 Fab heavy chain, TH236 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVI
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH236 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH236 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVH
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH132 Fab | Descriptor: | Spike glycoprotein, TH132 Fab heavy chain, TH132 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVG
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH132 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH132 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVF
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH027 Fab | Descriptor: | Spike glycoprotein, TH027 Fab heavy chain, TH027 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVE
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH027 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH027 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YV7
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7YV2
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7YV1
| Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor LUNA18 and KA30L Fab | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, KA30L Fab H-chain, ... | Authors: | Irie, M, Fukami, T.A, Matsuo, A, Saka, K, Nishimura, M, Saito, H, Torizawa, T, Tanada, M, Ohta, A. | Deposit date: | 2022-08-18 | Release date: | 2023-07-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.454 Å) | Cite: | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets. J.Am.Chem.Soc., 145, 2023
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7YUZ
| Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP8784 | Descriptor: | AP8784, GUANOSINE-5'-DIPHOSPHATE, IODIDE ION, ... | Authors: | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | Deposit date: | 2022-08-18 | Release date: | 2023-07-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.878 Å) | Cite: | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets. J.Am.Chem.Soc., 145, 2023
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7YUY
| Structure of a mutated membrane-bound glycosyltransferase | Descriptor: | (11R,14S)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate, 1,3-beta-glucan synthase component FKS1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Hu, X.L, Yang, P, Zhang, M, Liu, X.T, Yu, H.J. | Deposit date: | 2022-08-18 | Release date: | 2023-03-29 | Last modified: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural and mechanistic insights into fungal beta-1,3-glucan synthase FKS1. Nature, 616, 2023
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7YUK
| Complex structure of BANP BEN domain bound to DNA | Descriptor: | DNA (5'-D(*CP*TP*CP*TP*CP*GP*CP*GP*AP*GP*AP*G)-3'), GLYCEROL, Protein BANP | Authors: | Zhang, J, Xiao, Y.Q, Chen, Y.X, Liu, K, Min, J.R. | Deposit date: | 2022-08-17 | Release date: | 2023-04-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Structural insights into DNA recognition by the BEN domain of the transcription factor BANP. J.Biol.Chem., 299, 2023
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7YUJ
| Crystal structure of HOIL-1L(365-510) | Descriptor: | DI(HYDROXYETHYL)ETHER, RanBP-type and C3HC4-type zinc finger-containing protein 1, ZINC ION | Authors: | Xiao, L, Pan, L. | Deposit date: | 2022-08-17 | Release date: | 2023-08-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.865 Å) | Cite: | Mechanistic insights into the enzymatic activity of E3 ligase HOIL-1L and its regulation by the linear ubiquitin chain binding. Sci Adv, 9, 2023
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7YUI
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7YU8
| Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state4 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Akasaka, H, Shihoya, W, Nureki, O. | Deposit date: | 2022-08-16 | Release date: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YU7
| Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state3 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Akasaka, H, Shihoya, W, Nureki, O. | Deposit date: | 2022-08-16 | Release date: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YU6
| Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state2 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Akasaka, H, Shihoya, W, Nureki, O. | Deposit date: | 2022-08-16 | Release date: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YU5
| Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state1 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Akasaka, H, Shihoya, W, Nureki, O. | Deposit date: | 2022-08-16 | Release date: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YU4
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