7YU7

Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state3

Summary for 7YU7

• Entry DOI: 10.2210/pdb7yu7/pdb
• EMDB information: 34101
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Lysophosphatidic acid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
• Functional Keywords: gpcr, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 157779.35

Authors

Akasaka, H.,Shihoya, W.,Nureki, O. (deposition date: 2022-08-16, release date: 2022-10-05)

• Primary citation: Akasaka, H.,Tanaka, T.,Sano, F.K.,Matsuzaki, Y.,Shihoya, W.,Nureki, O.; Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist.; Nat Commun, 13:5417-5417, 2022; PubMed: 36109516; DOI: 10.1038/s41467-022-33121-2

Experimental method

ELECTRON MICROSCOPY (3.8 Å)