7YU4

Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, focused on receptor

Summary for 7YU4

Entry DOI	10.2210/pdb7yu4/pdb
EMDB information	34098
Descriptor	Lysophosphatidic acid receptor 1, [(2~{R})-2-[5-(2-hexylphenyl)pentanoylamino]-3-oxidanyl-propyl] dihydrogen phosphate (2 entities in total)
Functional Keywords	gpcr, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	43351.47
Authors	Akasaka, H.,Shihoya, W.,Nureki, O. (deposition date: 2022-08-16, release date: 2022-10-05)
Primary citation	Akasaka, H.,Tanaka, T.,Sano, F.K.,Matsuzaki, Y.,Shihoya, W.,Nureki, O. Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13:5417-5417, 2022 Cited by PubMed: 36109516 DOI: 10.1038/s41467-022-33121-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation