7YU4

Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, focused on receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Lysophosphatidic acid receptor 1	polymer	379	42936.0	1	UniProt (Q92633) Pfam (PF00001)	Homo sapiens (human)	LPA receptor 1,LPA-1,Lysophosphatidic acid receptor Edg-2
2	B (A)	[(2~{R})-2-[5-(2-hexylphenyl)pentanoylamino]-3-oxidanyl-propyl] dihydrogen phosphate	non-polymer		415.5	1	Chemie (K6L)

Sequence modifications

A: 2 - 364 (UniProt: Q92633)

PDB	External Database	Details
Asp -8	-	expression tag
Tyr -7	-	expression tag
Lys -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Ala -1	-	expression tag
Met 0	-	expression tag
Gly 1	-	expression tag
Glu 365	-	expression tag
Asn 366	-	expression tag
Leu 367	-	expression tag
Tyr 368	-	expression tag
Phe 369	-	expression tag
Gln 370	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42936.0
Non-Polymers*	Number of molecules	1
	Total formula weight	415.5
All*	Total formula weight	43351.5

*Water molecules are not included.