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4QL7
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Crystal structure of C-terminus truncated Alkylhydroperoxide Reductase subunit C (AhpC1-172) from E. coli
Descriptor: Alkylhydroperoxide Reductase subunit C
Authors:Kamariah, N, Gruber, G, Eisenhaber, F, Eisenhaber, B.
Deposit date:2014-06-11
Release date:2014-09-24
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Key roles of the Escherichia coli AhpC C-terminus in assembly and catalysis of alkylhydroperoxide reductase, an enzyme essential for the alleviation of oxidative stress.
Biochim.Biophys.Acta, 1837, 2014
4QL9
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BU of 4ql9 by Molmil
Crystal structure of C-terminus truncated Alkylhydroperoxide Reductase subunit C (AhpC1-182) from E. coli
Descriptor: Alkylhydroperoxide Reductase subunit C
Authors:Nartey, W, Kamariah, N, Gruber, G.
Deposit date:2014-06-11
Release date:2014-09-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Key roles of the Escherichia coli AhpC C-terminus in assembly and catalysis of alkylhydroperoxide reductase, an enzyme essential for the alleviation of oxidative stress.
Biochim.Biophys.Acta, 1837, 2014
1RJH
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BU of 1rjh by Molmil
Structure of the Calcium Free Form of the C-type Lectin-like Domain of Tetranectin
Descriptor: Tetranectin
Authors:Nielbo, S, Thomsen, J.K, Graversen, J.H, Etzerodt, M, Poulsen, F.M, Thoegersen, H.C.
Deposit date:2003-11-19
Release date:2004-07-20
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Structure of the Plasminogen Kringle 4 Binding Calcium-Free Form of the C-Type Lectin-Like Domain of Tetranectin.
Biochemistry, 43, 2004
6LBG
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BU of 6lbg by Molmil
Structure of OR51B2 bound FEM1C
Descriptor: Protein fem-1 homolog C,Peptide from Olfactory receptor 51B2, SULFATE ION
Authors:Chen, X, Liao, S, Xu, C.
Deposit date:2019-11-14
Release date:2020-10-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
5TRG
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BU of 5trg by Molmil
Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide DPLG-2
Descriptor: N,N-diethyl-N~2~-[(2E)-3-phenylprop-2-enoyl]-L-asparaginyl-4-fluoro-N-[(naphthalen-1-yl)methyl]-L-phenylalaninamide, Proteasome subunit alpha, Proteasome subunit beta
Authors:Hsu, H.-C, Fan, H, Singh, R.K, Wang, R, Sukenick, G, Nathan, C, Lin, G, Li, H.
Deposit date:2016-10-26
Release date:2017-01-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome.
Biochemistry, 56, 2017
6LE6
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Structure of LNLPTQGRAR bound FEM1C
Descriptor: Protein fem-1 homolog C,10-mer peptide, SULFATE ION
Authors:Chen, X, Liao, S, Xu, C.
Deposit date:2019-11-24
Release date:2020-10-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
2TN4
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BU of 2tn4 by Molmil
FOUR CALCIUM TNC
Descriptor: CALCIUM ION, TROPONIN C
Authors:Love, M.L, Dominguez, R, Houdusse, A, Cohen, C.
Deposit date:1997-09-18
Release date:1998-04-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of four Ca2+-bound troponin C at 2.0 A resolution: further insights into the Ca2+-switch in the calmodulin superfamily.
Structure, 5, 1997
3CJ0
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BU of 3cj0 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments
Descriptor: 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
1ERJ
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BU of 1erj by Molmil
CRYSTAL STRUCTURE OF THE C-TERMINAL WD40 DOMAIN OF TUP1
Descriptor: TRANSCRIPTIONAL REPRESSOR TUP1
Authors:Sprague, E.R, Redd, M.J, Johnson, A.D, Wolberger, C.
Deposit date:2000-04-06
Release date:2000-07-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast.
EMBO J., 19, 2000
2AX1
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BU of 2ax1 by Molmil
Hepatitis C Virus NS5b RNA Polymerase in complex with a covalent inhibitor (5ee)
Descriptor: 5R-(3,4-DICHLOROPHENYLMETHYL)-3-(2-THIOPHENESULFONYLAMINO)-4-OXO-2-THIONOTHIAZOLIDINE, Genome polyprotein, SULFATE ION
Authors:Powers, J.P, Piper, D.E, Li, Y, Mayorga, V, Anzola, J, Chen, J.M, Jaen, J.C, Lee, G, Liu, J, Peterson, M.G, Tonn, G.R, Ye, Q, Walker, N.P, Wang, Z.
Deposit date:2005-09-02
Release date:2006-01-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase.
J.Med.Chem., 49, 2006
3CJ3
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BU of 3cj3 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ2
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
2EDN
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BU of 2edn by Molmil
Solution structure of the first ig-like domain from human Myosin-binding protein C, fast-type
Descriptor: Myosin-binding protein C, fast-type
Authors:Nagashima, K, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-14
Release date:2007-08-14
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the first ig-like domain from human Myosin-binding protein C, fast-type
To be Published
2VIF
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BU of 2vif by Molmil
Crystal structure of SOCS6 SH2 domain in complex with a c-KIT phosphopeptide
Descriptor: 1,2-ETHANEDIOL, MAST/STEM CELL GROWTH FACTOR RECEPTOR, SUPPRESSOR OF CYTOKINE SIGNALLING 6
Authors:Bullock, A, Pike, A.C.W, Savitsky, P, Keates, T, Pilka, E.S, von Delft, F, Edwards, A, Weigelt, J, Arrowsmith, C.H, Knapp, S.
Deposit date:2007-11-30
Release date:2007-12-25
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural Basis for C-Kit Inhibition by the Suppressor of Cytokine Signaling 6 (Socs6) Ubiquitin Ligase.
J.Biol.Chem., 286, 2011
7CLZ
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BU of 7clz by Molmil
Crystal structure of Alp1U W187F/Y247F in complex with fluostatin C
Descriptor: BORIC ACID, D-MALATE, Fluostatin C, ...
Authors:Zhang, L, De, B.C.
Deposit date:2020-07-22
Release date:2020-10-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.10001016 Å)
Cite:Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the alpha / beta-fold epoxide hydrolase Alp1U.
J.Biol.Chem., 295, 2020
1H4J
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BU of 1h4j by Molmil
Methylobacterium extorquens methanol dehydrogenase D303E mutant
Descriptor: CALCIUM ION, Methanol dehydrogenase [cytochrome c] subunit 1, Methanol dehydrogenase [cytochrome c] subunit 2, ...
Authors:Mohammed, F, Gill, R, Thompson, D, Cooper, J.B, Wood, S.P, Afolabi, P.R, Anthony, C.
Deposit date:2001-05-11
Release date:2001-08-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Site-Directed Mutagenesis and X-Ray Crystallography of the Pqq-Containing Quinoprotein Methanol Dehydrogenase and its Electron Acceptor, Cytochrome C(L)(,)
Biochemistry, 40, 2001
2QEE
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BU of 2qee by Molmil
Crystal structure of putative amidohydrolase BH0493 from Bacillus halodurans C-125
Descriptor: BH0493 protein, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Malashkevich, V.N, Toro, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-06-25
Release date:2007-07-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of putative amidohydrolase BH0493 from Bacillus halodurans C-125.
To be Published
2AWZ
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BU of 2awz by Molmil
Hepatitis C Virus NS5b RNA Polymerase in complex with a covalent inhibitor (5h)
Descriptor: 5R-(4-BROMOPHENYLMETHYL)-3-(BENZENESULFONYLAMINO)-4-OXO-2-THIONOTHIAZOLIDINE, Genome polyprotein, SULFATE ION
Authors:Powers, J.P, Piper, D.E, Li, Y, Mayorga, V, Anzola, J, Chen, J.M, Jaen, J.C, Lee, G, Liu, J, Peterson, M.G, Tonn, G.R, Ye, Q, Walker, N.P, Wang, Z.
Deposit date:2005-09-02
Release date:2006-01-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase.
J.Med.Chem., 49, 2006
3QGH
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BU of 3qgh by Molmil
Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase genotype 1a complex with N-cyclopropyl-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide
Descriptor: N-cyclopropyl-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide, PHOSPHATE ION, RNA-directed RNA polymerase
Authors:Sheriff, S.
Deposit date:2011-01-24
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase.
Bioorg.Med.Chem.Lett., 21, 2011
3SS3
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BU of 3ss3 by Molmil
Crystal structure of mouse Glutaminase C, ligand-free form
Descriptor: CHLORIDE ION, Glutaminase C
Authors:Ambrosio, A.L.B, Dias, S.M.G, Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
2JDL
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BU of 2jdl by Molmil
Structure of C-terminal region of acidic P2 ribosomal protein complexed with trichosanthin
Descriptor: ACIDIC RIBOSOMAL PROTEIN P2, RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN
Authors:Too, P.H, Mak, A.N, Zhu, G, Au, S.W, Wong, K.B, Shaw, P.C.
Deposit date:2007-01-11
Release date:2008-02-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The C-Terminal Fragment of the Ribosomal P Protein Complexed to Trichosanthin Reveals the Interaction between the Ribosome-Inactivating Protein and the Ribosome.
Nucleic Acids Res., 37, 2009
3SS5
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BU of 3ss5 by Molmil
Crystal structure of mouse Glutaminase C, L-glutamate-bound form
Descriptor: GLUTAMIC ACID, Glutaminase C
Authors:Ambrosio, A.L.B, Dias, S.M.G, Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
1H3M
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BU of 1h3m by Molmil
Structure of 4-diphosphocytidyl-2C-methyl-D-erythritol synthetase
Descriptor: 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLORIDE ION, PENTANE-1,5-DIAMINE
Authors:Kemp, L.E, Bond, C.S, Hunter, W.N.
Deposit date:2002-09-10
Release date:2003-08-01
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a Tetragonal Crystal Form of Escherichia Coli 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase
Acta Crystallogr.,Sect.D, 59, 2003
3PYD
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BU of 3pyd by Molmil
crystal structure of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis
Descriptor: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, GLYCEROL
Authors:Shan, S, Chen, X.H, Liu, T, Zhao, H.C, Rao, Z.H, Lou, Z.Y.
Deposit date:2010-12-13
Release date:2012-01-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:The Structural Basis for anti-TB Drug Discovery targeting of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis
To be Published
1HEI
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BU of 1hei by Molmil
STRUCTURE OF THE HEPATITIS C VIRUS RNA HELICASE DOMAIN
Descriptor: CALCIUM ION, HCV HELICASE
Authors:Yao, N, Weber, P.
Deposit date:1997-03-31
Release date:1998-10-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the hepatitis C virus RNA helicase domain.
Nat.Struct.Biol., 4, 1997

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