Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2VIF

Crystal structure of SOCS6 SH2 domain in complex with a c-KIT phosphopeptide

Summary for 2VIF
Entry DOI10.2210/pdb2vif/pdb
Related1PKG 1QZJ 1QZK 1R01 1T45 1T46
DescriptorSUPPRESSOR OF CYTOKINE SIGNALLING 6, MAST/STEM CELL GROWTH FACTOR RECEPTOR, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsgrowth regulation, signal transduction inhibitor, kit regulator, phosphotyrosine, signaling protein
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationMembrane; Single-pass type I membrane protein: P10721
Total number of polymer chains2
Total formula weight17330.08
Authors
Bullock, A.,Pike, A.C.W.,Savitsky, P.,Keates, T.,Pilka, E.S.,von Delft, F.,Edwards, A.,Weigelt, J.,Arrowsmith, C.H.,Knapp, S. (deposition date: 2007-11-30, release date: 2007-12-25, Last modification date: 2023-12-13)
Primary citationZadjali, F.,Pike, A.C.W.,Vesterlund, M.,Sun, J.,Wu, C.,Li, S.S.,Ronnstrand, L.,Knapp, S.,Bullock, A.,Flores-Morales, A.
Structural Basis for C-Kit Inhibition by the Suppressor of Cytokine Signaling 6 (Socs6) Ubiquitin Ligase.
J.Biol.Chem., 286:480-, 2011
Cited by
PubMed: 21030588
DOI: 10.1074/JBC.M110.173526
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.45 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon