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7JUM
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BU of 7jum by Molmil
Pfs230 D1 domain in complex with neutralizing antibody LMIV230-01
Descriptor: Gametocyte surface protein P230, Neutralizing antibody, LMIV230-01 Single-chain Fv
Authors:Tolia, N, Tang, W.K.
Deposit date:2020-08-20
Release date:2021-03-31
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes.
Nat Commun, 12, 2021
6NC2
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BU of 6nc2 by Molmil
AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody ACS202 fragment antigen binding
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC011 v4.2 SOSIP gp120, ...
Authors:Cottrell, C.A, Ozorowski, G, Yuan, M, Copps, J, Wilson, I.A, Ward, A.B.
Deposit date:2018-12-10
Release date:2019-06-19
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies.
Cell Host Microbe, 25, 2019
6NC3
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BU of 6nc3 by Molmil
AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody VRC34 fragment antigen binding
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env AMC011 v4.2 SOSIP gp120, ...
Authors:Cottrell, C.A, Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2018-12-10
Release date:2019-06-19
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies.
Cell Host Microbe, 25, 2019
7CHY
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BU of 7chy by Molmil
Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26
Descriptor: Interleukin-1 beta, heavy chain of antibody binding fragment of IgG26, light chain of antibody binding fragment of IgG26
Authors:Lee, C.C, Wang, A.H.J, Kuo, W.C.
Deposit date:2020-07-06
Release date:2021-01-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP.
J.Mol.Biol., 433, 2020
7CHZ
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BU of 7chz by Molmil
Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26A
Descriptor: Interleukin-1 beta, heavy chain of antibody binding fragment of IgG26A, light chain of antibody binding fragment of IgG26A
Authors:Lee, C.C, Wang, A.H.J, Kuo, W.C.
Deposit date:2020-07-06
Release date:2021-01-13
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP.
J.Mol.Biol., 433, 2020
7KC9
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BU of 7kc9 by Molmil
Ricin bound to VHH antibody V5G1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ricin chain A, ...
Authors:Rudolph, M.J.
Deposit date:2020-10-05
Release date:2021-08-04
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface.
J.Mol.Biol., 433, 2021
7KD2
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BU of 7kd2 by Molmil
Ricin bound to VHH antibody V11B2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ricin chain A, ...
Authors:Rudolph, M.J.
Deposit date:2020-10-07
Release date:2021-08-04
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface.
J.Mol.Biol., 433, 2021
7FCP
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BU of 7fcp by Molmil
Crystallographic structure of two neutralizing antibodies in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Zheng, P, Jin, T.
Deposit date:2021-07-15
Release date:2022-06-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance.
J.Clin.Invest., 132, 2022
7FAH
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BU of 7fah by Molmil
Immune complex of head region of CA09 HA and neutralizing antibody 12H5
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Li, T.T, Xue, W.H, Gu, Y, Li, S.W.
Deposit date:2021-07-06
Release date:2022-07-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.151 Å)
Cite:Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses.
Nat Commun, 13, 2022
3K81
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BU of 3k81 by Molmil
Structure of the central interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies
Descriptor: MP18 RNA editing complex protein, Single strand antibody VHH domain
Authors:Park, Y.-J, Hol, W.
Deposit date:2009-10-13
Release date:2010-11-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.
J.Struct.Biol., 174, 2011
7TCC
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BU of 7tcc by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike in complex with antibodies A19-46.1 and B1-182.1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody A19-46.1, ...
Authors:Zhou, T, Kwong, P.D.
Deposit date:2021-12-23
Release date:2022-03-30
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
6OBM
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BU of 6obm by Molmil
Ricin A chain bound to VHH antibody V6A7
Descriptor: CHLORIDE ION, Ricin A chain, VHH antibody V6A7
Authors:Rudolph, M.J.
Deposit date:2019-03-21
Release date:2020-04-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.495 Å)
Cite:Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
6OSY
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BU of 6osy by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-a.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
Descriptor: 0PV-a.01 Heavy, 0PV-a.01 Light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2019-05-02
Release date:2019-07-24
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
7U0D
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BU of 7u0d by Molmil
Local refinement of cryo-EM structure of the interface of the Omicron RBD in complex with antibodies B-182.1 and A19-46.1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 antibody A19-46.1, Heavy chain of SARS-CoV-2 antibody B1-182.1, ...
Authors:Zhou, T, kwong, P.D.
Deposit date:2022-02-17
Release date:2022-03-30
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7UEM
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BU of 7uem by Molmil
Genomic and structural basis for the human anti-alpha-galactosyl antibody response
Descriptor: CHLORIDE ION, Heavy chain Fab arm of antibody HKB7, Light chain Fab of antibody HKB7, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2022-03-22
Release date:2022-06-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.314 Å)
Cite:Genetic and structural basis of the human anti-alpha-galactosyl antibody response.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UEN
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BU of 7uen by Molmil
Genetic and structural basis of the human anti-alpha-galactosyl antibody response
Descriptor: M86 antibody Fab heavy chain, M86 antibody Fab light chain, PHOSPHATE ION, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2022-03-22
Release date:2022-06-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Genetic and structural basis of the human anti-alpha-galactosyl antibody response.
Proc.Natl.Acad.Sci.USA, 119, 2022
6N1W
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BU of 6n1w by Molmil
Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody DFPH-a.15 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DFPH-a.15 Light chain, ...
Authors:Acharya, P, Kwong, P.D.
Deposit date:2018-11-12
Release date:2019-07-24
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MPG
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BU of 6mpg by Molmil
Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-b.01 Heavy Chain, ...
Authors:Acharya, P, Kwong, P.D.
Deposit date:2018-10-06
Release date:2019-07-24
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6OBG
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BU of 6obg by Molmil
Ricin A chain bound to VHH antibody V8E6
Descriptor: CHLORIDE ION, Ricin A chain, VHH antibody V8E6, ...
Authors:Rudolph, M.J.
Deposit date:2019-03-20
Release date:2020-04-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
6OT1
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BU of 6ot1 by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
Descriptor: 0PV-b.01 heavy, 0PV-b.01 light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2019-05-02
Release date:2019-08-07
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6OCA
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BU of 6oca by Molmil
Ricin A chain bound to VHH antibody V2G10
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Ricin A chain, ...
Authors:Rudolph, M.J.
Deposit date:2019-03-22
Release date:2020-04-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.113 Å)
Cite:Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
6OBE
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BU of 6obe by Molmil
Ricin A chain bound to VHH antibody V6H8
Descriptor: 1,2-ETHANEDIOL, IMIDAZOLE, NICKEL (II) ION, ...
Authors:Rudolph, M.J.
Deposit date:2019-03-20
Release date:2020-04-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.732 Å)
Cite:Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
6OBO
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BU of 6obo by Molmil
Ricin A chain bound to VHH antibody V6A6
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ...
Authors:Rudolph, M.J.
Deposit date:2019-03-21
Release date:2020-04-01
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
7UEL
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BU of 7uel by Molmil
Genetic and structural basis for the human anti-alpha-galactosyl antibody response
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Heavy chain Fab of antibody JEC1, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2022-03-22
Release date:2022-06-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Genetic and structural basis of the human anti-alpha-galactosyl antibody response.
Proc.Natl.Acad.Sci.USA, 119, 2022
8R9W
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BU of 8r9w by Molmil
PDCoV spike glycoprotein ectodomain in complex with the 22C10 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 22C10 antibody heavy chain, ...
Authors:Debski-Antoniak, O, Hurdiss, D.L.
Deposit date:2023-11-30
Release date:2024-06-05
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein.
Nat Commun, 15, 2024

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数据于2024-11-06公开中

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