5Y48
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![BU of 5y48 by Molmil](/molmil-images/mine/5y48) | Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina with Pyrimidine-2,4-dione at 1.70 Angstrom resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Ribosome inactivating protein, URACIL | Authors: | Singh, P.K, Pandey, S, Iqbal, N, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2017-08-01 | Release date: | 2017-09-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Binding and structural studies of the complexes of type 1 ribosome inactivating protein from Momordica balsamina with uracil and uridine. Proteins, 87, 2019
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5WV1
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![BU of 5wv1 by Molmil](/molmil-images/mine/5wv1) | Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina with ribose sugar at 1.90 A resolution. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ribosome inactivating protein, ... | Authors: | Shokeen, A, Singh, P.K, Pandey, S, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2016-12-21 | Release date: | 2017-01-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina with ribose sugar at
1.90 A resolution. To Be Published
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5Z3I
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![BU of 5z3i by Molmil](/molmil-images/mine/5z3i) | |
5Z3J
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![BU of 5z3j by Molmil](/molmil-images/mine/5z3j) | |
5Z37
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![BU of 5z37 by Molmil](/molmil-images/mine/5z37) | |
6LOV
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![BU of 6lov by Molmil](/molmil-images/mine/6lov) | crystal structure of alpha-momorcharin in complex with xanthosine | Descriptor: | 2,3-dihydroxanthosine, Ribosome-inactivating protein momordin I | Authors: | Fan, X, Jin, T. | Deposit date: | 2020-01-07 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020
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6LOQ
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![BU of 6loq by Molmil](/molmil-images/mine/6loq) | crystal structure of alpha-momorcharin in complex with cAMP | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Ribosome-inactivating protein momordin I | Authors: | Fan, X, Jin, T. | Deposit date: | 2020-01-07 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.331 Å) | Cite: | Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020
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6LOY
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![BU of 6loy by Molmil](/molmil-images/mine/6loy) | crystal structure of alpha-momorcharin in complex with dAMP | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Ribosome-inactivating protein momordin I | Authors: | Fan, X, Jin, T. | Deposit date: | 2020-01-07 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020
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7TH3
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![BU of 7th3 by Molmil](/molmil-images/mine/7th3) | Single-domain VHH intrabodies neutralize ricin toxin | Descriptor: | Ricin chain A, VHH antibody | Authors: | Rudolph, M.J. | Deposit date: | 2022-01-10 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.292 Å) | Cite: | Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins. J.Biol.Chem., 298, 2022
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7TH2
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![BU of 7th2 by Molmil](/molmil-images/mine/7th2) | Single-domain VHH intrabodies neutralize ricin toxin | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2022-01-10 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.838 Å) | Cite: | Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins. J.Biol.Chem., 298, 2022
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7TGF
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![BU of 7tgf by Molmil](/molmil-images/mine/7tgf) | Single-domain VHH intrabodies neutralize ricin toxin. | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Ricin chain A, ... | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2022-01-07 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.347 Å) | Cite: | Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins. J.Biol.Chem., 298, 2022
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7TGI
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![BU of 7tgi by Molmil](/molmil-images/mine/7tgi) | Single-domain VHH intrabodies neutralize ricin toxin | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Ricin chain A, ... | Authors: | Rudolph, M.J. | Deposit date: | 2022-01-07 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.104 Å) | Cite: | Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins. J.Biol.Chem., 298, 2022
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8TAB
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![BU of 8tab by Molmil](/molmil-images/mine/8tab) | RTA-PD00589 | Descriptor: | 1,2-ETHANEDIOL, 4H,5H-naphtho[1,2-b]thiophene-2-carboxylic acid, CHLORIDE ION, ... | Authors: | Rudolph, M.J, Tumer, N. | Deposit date: | 2023-06-27 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin. Bioorg.Med.Chem., 100, 2024
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8T9V
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![BU of 8t9v by Molmil](/molmil-images/mine/8t9v) | RTA-RUNT-59 complex structure | Descriptor: | (9aP)-7-fluoro-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylic acid, NONAETHYLENE GLYCOL, Ricin | Authors: | Rudolph, M.J, Tumer, N. | Deposit date: | 2023-06-26 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.945 Å) | Cite: | Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin. Bioorg.Med.Chem., 100, 2024
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8TAD
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![BU of 8tad by Molmil](/molmil-images/mine/8tad) | RTA in complex with inhibitor RUNT-206 | Descriptor: | (9aM)-5,5-dimethyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylic acid, CHLORIDE ION, NONAETHYLENE GLYCOL, ... | Authors: | Rudolph, M.J, Tumer, N. | Deposit date: | 2023-06-27 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin. Bioorg.Med.Chem., 100, 2024
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8SZ2
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![BU of 8sz2 by Molmil](/molmil-images/mine/8sz2) | Stx2A1 bound to P8 stalk peptide | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, NONAETHYLENE GLYCOL, ... | Authors: | rudolph, M.J, Li, X.P. | Deposit date: | 2023-05-26 | Release date: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structure of Shiga toxin 2 A1 subunit with peptides that bind at the ribosome binding site and inhibit activity To Be Published
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6OCD
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![BU of 6ocd by Molmil](/molmil-images/mine/6ocd) | Ricin A chain bound to VHH antibody V6D4 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, IMIDAZOLE, ... | Authors: | Rudolph, M.J. | Deposit date: | 2019-03-22 | Release date: | 2020-04-01 | Last modified: | 2020-10-14 | Method: | X-RAY DIFFRACTION (2.103 Å) | Cite: | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site. J.Mol.Biol., 432, 2020
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2Z4U
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6OBM
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![BU of 6obm by Molmil](/molmil-images/mine/6obm) | Ricin A chain bound to VHH antibody V6A7 | Descriptor: | CHLORIDE ION, Ricin A chain, VHH antibody V6A7 | Authors: | Rudolph, M.J. | Deposit date: | 2019-03-21 | Release date: | 2020-04-01 | Last modified: | 2020-10-14 | Method: | X-RAY DIFFRACTION (2.495 Å) | Cite: | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site. J.Mol.Biol., 432, 2020
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6OCA
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![BU of 6oca by Molmil](/molmil-images/mine/6oca) | Ricin A chain bound to VHH antibody V2G10 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Ricin A chain, ... | Authors: | Rudolph, M.J. | Deposit date: | 2019-03-22 | Release date: | 2020-04-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.113 Å) | Cite: | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site. J.Mol.Biol., 432, 2020
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2Z53
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3BWH
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![BU of 3bwh by Molmil](/molmil-images/mine/3bwh) | Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, beta-D-xylopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)][alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L. | Deposit date: | 2008-01-09 | Release date: | 2008-10-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Atomic resolution structure of cucurmosin, a novel type 1 ribosome-inactivating protein from the sarcocarp of Cucurbita moschata. J.Struct.Biol., 164, 2008
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3CTK
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![BU of 3ctk by Molmil](/molmil-images/mine/3ctk) | Crystal structure of the type 1 RIP bouganin | Descriptor: | rRNA N-glycosidase | Authors: | Fermani, S, Tosi, G, Falini, G, Ripamonti, A, Farini, V, Bolognesi, A, Polito, L. | Deposit date: | 2008-04-14 | Release date: | 2008-05-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure/function studies on two type 1 ribosome inactivating proteins: Bouganin and lychnin. J.Struct.Biol., 168, 2009
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5BOZ
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![BU of 5boz by Molmil](/molmil-images/mine/5boz) | Ricin A chain bound to camelid nanobody (VHH9)(E1) | Descriptor: | CHLORIDE ION, Ricin, SULFATE ION, ... | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2015-05-27 | Release date: | 2016-12-07 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit. J. Biol. Chem., 292, 2017
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1F8Q
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![BU of 1f8q by Molmil](/molmil-images/mine/1f8q) | CRYSTAL STRUCTURE OF ALPHA-MOMORCHARIN IN ACETONITRILE-WATER MIXTURE | Descriptor: | ACETONITRILE, ALPHA-MOMORCHARIN, PENTANEDIAL, ... | Authors: | Zhu, G, Huang, Q, Qian, M, Tang, Y. | Deposit date: | 2000-07-03 | Release date: | 2000-07-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of alpha-momorcharin in 80% acetonitrile--water mixture BIOCHIM.BIOPHYS.ACTA, 1548, 2001
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