8TAB

RTA-PD00589

Summary for 8TAB

• Entry DOI: 10.2210/pdb8tab/pdb
• Descriptor: Ricin A chain, CHLORIDE ION, 4H,5H-naphtho[1,2-b]thiophene-2-carboxylic acid, ... (6 entities in total)
• Functional Keywords: n-glycosidase, inhibitor, toxin, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Ricinus communis (castor bean)
• Total number of polymer chains: 1
• Total formula weight: 29810.89

Authors

Rudolph, M.J.,Tumer, N. (deposition date: 2023-06-27, release date: 2024-05-01)

• Primary citation: Rudolph, M.J.,Dutta, A.,Tsymbal, A.M.,McLaughlin, J.E.,Chen, Y.,Davis, S.A.,Theodorous, S.A.,Pierce, M.,Algava, B.,Zhang, X.,Szekely, Z.,Roberge, J.Y.,Li, X.P.,Tumer, N.E.; Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin.; Bioorg.Med.Chem., 100:117614-117614, 2024; PubMed: 38340640; DOI: 10.1016/j.bmc.2024.117614

Experimental method

X-RAY DIFFRACTION (2.26 Å)