2XRB
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![BU of 2xrb by Molmil](/molmil-images/mine/2xrb) | Structure of the N-terminal four domains of the complement regulator Rat Crry | Descriptor: | 1,2-ETHANEDIOL, COMPLEMENT REGULATORY PROTEIN CRRY, SULFATE ION | Authors: | Leath, K.J, Roversi, P, Johnson, S, Morgan, B.P, Lea, S.M. | Deposit date: | 2010-09-13 | Release date: | 2011-06-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of the Rat Complement Regulator Crry. Acta Crystallogr.,Sect.F, 67, 2011
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2UWN
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![BU of 2uwn by Molmil](/molmil-images/mine/2uwn) | Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand. | Descriptor: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACETATE ION, CHLORIDE ION, ... | Authors: | Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Terelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M. | Deposit date: | 2007-03-22 | Release date: | 2007-10-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration. J.Exp.Med., 204, 2007
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1SRZ
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![BU of 1srz by Molmil](/molmil-images/mine/1srz) | Solution structure of the second complement control protein (CCP) module of the GABA(B)R1a receptor, Pro-119 trans conformer | Descriptor: | Gamma-aminobutyric acid type B receptor, subunit 1 | Authors: | Blein, S, Uhrin, D, Smith, B.O, White, J.H, Barlow, P.N. | Deposit date: | 2004-03-23 | Release date: | 2004-10-12 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Structural Analysis of the Complement Control Protein (CCP) Modules of GABAB Receptor 1a: ONLY ONE OF THE TWO CCP MODULES IS COMPACTLY FOLDED J.Biol.Chem., 279, 2004
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1UOT
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![BU of 1uot by Molmil](/molmil-images/mine/1uot) | HUMAN CD55 DOMAINS 3 & 4 | Descriptor: | COMPLEMENT DECAY-ACCELERATING FACTOR | Authors: | Williams, P, Chaudhry, Y, Goodfellow, I.G, Billington, J, Spiller, B, Evans, D.J, Lea, S.M. | Deposit date: | 2003-09-23 | Release date: | 2003-09-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A J.Biol.Chem., 278, 2003
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1VVE
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![BU of 1vve by Molmil](/molmil-images/mine/1vve) | |
1SS2
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![BU of 1ss2 by Molmil](/molmil-images/mine/1ss2) | Solution structure of the second complement control protein (CCP) module of the GABA(B)R1a receptor, Pro-119 cis conformer | Descriptor: | Gamma-aminobutyric acid type B receptor, subunit 1 | Authors: | Blein, S, Uhrin, D, Smith, B.O, White, J.H, Barlow, P.N. | Deposit date: | 2004-03-23 | Release date: | 2004-10-12 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Structural analysis of the complement control protein (CCP) modules of GABA(B) receptor 1a: only one of the two CCP modules is compactly folded. J.Biol.Chem., 279, 2004
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1W2R
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![BU of 1w2r by Molmil](/molmil-images/mine/1w2r) | Solution structure of CR2 SCR 1-2 by X-ray scattering | Descriptor: | COMPLEMENT RECEPTOR TYPE 2 PRECURSOR, | Authors: | Gilbert, H.E, Hannan, J.P, Holers, V.M, Perkins, S.J. | Deposit date: | 2004-07-08 | Release date: | 2005-09-29 | Last modified: | 2024-05-08 | Method: | SOLUTION SCATTERING | Cite: | Solution Structure of the Complex between Cr2 Scr 1-2 and C3D of Human Complement: An X-Ray Scattering and Sedimentation Modelling Study. J.Mol.Biol., 346, 2005
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3GAW
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![BU of 3gaw by Molmil](/molmil-images/mine/3gaw) | |
3J24
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![BU of 3j24 by Molmil](/molmil-images/mine/3j24) | CryoEM reconstruction of complement decay-accelerating factor | Descriptor: | Complement decay-accelerating factor | Authors: | Yoder, J.D, Hafenstein, S.H. | Deposit date: | 2012-08-17 | Release date: | 2012-09-26 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | The Crystal Structure of a Coxsackievirus B3-RD Variant and a Refined 9-Angstrom Cryo-Electron Microscopy Reconstruction of the Virus Complexed with Decay-Accelerating Factor (DAF) Provide a New Footprint of DAF on the Virus Surface. J.Virol., 86, 2012
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2MCZ
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![BU of 2mcz by Molmil](/molmil-images/mine/2mcz) | CR1 Sushi domains 1 and 2 | Descriptor: | Complement receptor type 1 | Authors: | Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P. | Deposit date: | 2013-08-27 | Release date: | 2013-11-13 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor. J.Biol.Chem., 289, 2014
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4B2R
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![BU of 4b2r by Molmil](/molmil-images/mine/4b2r) | Solution structure of CCP modules 10-11 of complement factor H | Descriptor: | COMPLEMENT FACTOR H | Authors: | Makou, E, Mertens, H.D.T, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N. | Deposit date: | 2012-07-17 | Release date: | 2012-10-10 | Last modified: | 2019-09-25 | Method: | SOLUTION NMR | Cite: | Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H. J.Mol.Biol., 424, 2012
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2Q7Z
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![BU of 2q7z by Molmil](/molmil-images/mine/2q7z) | Solution Structure of the 30 SCR domains of human Complement Receptor 1 | Descriptor: | Complement receptor type 1 | Authors: | Furtado, P.B, Huang, C.Y, Ihyembe, D, Hammond, R.A, Marsh, H.C, Perkins, S.J. | Deposit date: | 2007-06-08 | Release date: | 2007-10-16 | Last modified: | 2024-02-21 | Method: | SOLUTION SCATTERING | Cite: | The Partly Folded Back Solution Structure Arrangement of the 30 SCR Domains in Human Complement Receptor Type 1 (CR1) Permits Access to its C3b and C4b Ligands J.Mol.Biol., 375, 2008
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2QFG
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![BU of 2qfg by Molmil](/molmil-images/mine/2qfg) | Solution Structure of the N-terminal SCR-1/5 fragment of Complement Factor H. | Descriptor: | Complement factor H | Authors: | Okemefuna, A.I, Gilbert, H.E, Griggs, K.M, Ormsby, R.J, Gordon, D.L, Perkins, S.J. | Deposit date: | 2007-06-27 | Release date: | 2007-09-25 | Last modified: | 2024-02-21 | Method: | SOLUTION SCATTERING | Cite: | The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties. J.Mol.Biol., 375, 2008
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2MCY
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![BU of 2mcy by Molmil](/molmil-images/mine/2mcy) | CR1 Sushi domains 2 and 3 | Descriptor: | Complement receptor type 1 | Authors: | Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P. | Deposit date: | 2013-08-27 | Release date: | 2013-11-13 | Last modified: | 2014-01-22 | Method: | SOLUTION NMR | Cite: | Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor. J.Biol.Chem., 289, 2014
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2QZH
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![BU of 2qzh by Molmil](/molmil-images/mine/2qzh) | SCR2/3 of DAF from the NMR structure 1nwv fitted into a cryoEM reconstruction of CVB3-RD complexed with DAF | Descriptor: | Complement decay-accelerating factor | Authors: | Hafenstein, S, Bowman, V.D, Chipman, P.R, Bator Kelly, C.M, Lin, F, Medof, M.E, Rossmann, M.G. | Deposit date: | 2007-08-16 | Release date: | 2007-10-30 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (14 Å) | Cite: | Interaction of decay-accelerating factor with coxsackievirus b3. J.Virol., 81, 2007
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2QZF
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![BU of 2qzf by Molmil](/molmil-images/mine/2qzf) | SCR1 of DAF from 1ojv fitted into cryoEM density | Descriptor: | Complement decay-accelerating factor | Authors: | Hafenstein, S, Bowman, V.D, Chipman, P.R, Bator Kelly, C.M, Lin, F, Medof, M.E, Rossmann, M.G. | Deposit date: | 2007-08-16 | Release date: | 2007-10-30 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (14 Å) | Cite: | Interaction of decay-accelerating factor with coxsackievirus b3. J.Virol., 81, 2007
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7ZJM
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![BU of 7zjm by Molmil](/molmil-images/mine/7zjm) | Crystal structure of a complex between CspZ from Borrelia burgdorferi strain B408 and human FH SCR domains 6-7 | Descriptor: | Complement factor H, CspZ, DI(HYDROXYETHYL)ETHER, ... | Authors: | Brangulis, K, Marcinkiewicz, A, Hart, T.M, Dupuis, A.P, Zamba Campero, M, Nowak, T.A, Stout, J.L, Akopjana, I, Kazaks, A, Bogans, J, Ciota, A.T, Kraiczy, P, Kolokotronis, S.O, Lin, Y.-P. | Deposit date: | 2022-04-11 | Release date: | 2023-04-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structural evolution of an immune evasion determinant shapes pathogen host tropism. Proc.Natl.Acad.Sci.USA, 120, 2023
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8ACI
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![BU of 8aci by Molmil](/molmil-images/mine/8aci) | |
8ACF
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![BU of 8acf by Molmil](/molmil-images/mine/8acf) | |
1GKG
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![BU of 1gkg by Molmil](/molmil-images/mine/1gkg) | Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35) | Descriptor: | COMPLEMENT RECEPTOR TYPE 1 | Authors: | Smith, B.O, Mallin, R.L, Krych-Goldberg, M, Wang, X, Hauhart, R.E, Bromek, K, Uhrin, D, Atkinson, J.P, Barlow, P.N. | Deposit date: | 2001-08-14 | Release date: | 2002-04-18 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor Cell(Cambridge,Mass.), 108, 2002
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1PPQ
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![BU of 1ppq by Molmil](/molmil-images/mine/1ppq) | NMR structure of 16th module of Immune Adherence Receptor, Cr1 (Cd35) | Descriptor: | Complement receptor type 1 | Authors: | O'Leary, J.M, Bromek, K, Black, G.M, Uhrinova, S, Schmitz, C, Krych, M, Atkinson, J.P, Uhrin, D, Barlow, P.N. | Deposit date: | 2003-06-17 | Release date: | 2004-05-04 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces. Protein Sci., 13, 2004
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1GKN
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![BU of 1gkn by Molmil](/molmil-images/mine/1gkn) | Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35) | Descriptor: | COMPLEMENT RECEPTOR TYPE 1 | Authors: | Smith, B.O, Mallin, R.L, Krych-Goldberg, M, Wang, X, Hauhart, R.E, Bromek, K, Uhrin, D, Atkinson, J.P, Barlow, P.N. | Deposit date: | 2001-08-16 | Release date: | 2002-04-18 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor Cell(Cambridge,Mass.), 108, 2002
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1H03
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![BU of 1h03 by Molmil](/molmil-images/mine/1h03) | Human CD55 domains 3 & 4 | Descriptor: | COMPLEMENT DECAY-ACCELERATING FACTOR | Authors: | Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Spiller, B, Evans, D.J, Lea, S.M. | Deposit date: | 2002-06-11 | Release date: | 2003-03-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A J.Biol.Chem., 278, 2003
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1H04
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![BU of 1h04 by Molmil](/molmil-images/mine/1h04) | Human CD55 domains 3 & 4 | Descriptor: | COMPLEMENT DECAY-ACCELERATING FACTOR, NICKEL (II) ION | Authors: | Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Spiller, B, Evans, D.J, Lea, S.M. | Deposit date: | 2002-06-11 | Release date: | 2003-03-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A J.Biol.Chem., 278, 2003
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1H2P
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![BU of 1h2p by Molmil](/molmil-images/mine/1h2p) | Human CD55 domains 3 & 4 | Descriptor: | COMPLEMENT DECAY-ACCELERATING FACTOR | Authors: | Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Spiller, B, Evans, D.J, Lea, S.M. | Deposit date: | 2002-08-13 | Release date: | 2003-03-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A J.Biol.Chem., 278, 2003
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