7ZJM

Crystal structure of a complex between CspZ from Borrelia burgdorferi strain B408 and human FH SCR domains 6-7

Summary for 7ZJM

• Entry DOI: 10.2210/pdb7zjm/pdb
• Descriptor: CspZ, Complement factor H, ZINC ION, ... (6 entities in total)
• Functional Keywords: lyme disease, complement system, borreliosis, bbh06., immune system
• Biological source: Borreliella burgdorferi (Lyme disease spirochete); More
• Total number of polymer chains: 2
• Total formula weight: 40739.59

Authors

Brangulis, K.,Marcinkiewicz, A.,Hart, T.M.,Dupuis, A.P.,Zamba Campero, M.,Nowak, T.A.,Stout, J.L.,Akopjana, I.,Kazaks, A.,Bogans, J.,Ciota, A.T.,Kraiczy, P.,Kolokotronis, S.O.,Lin, Y.-P. (deposition date: 2022-04-11, release date: 2023-04-19, Last modification date: 2024-02-07)

• Primary citation: Marcinkiewicz, A.L.,Brangulis, K.,Dupuis 2nd, A.P.,Hart, T.M.,Zamba-Campero, M.,Nowak, T.A.,Stout, J.L.,Akopjana, I.,Kazaks, A.,Bogans, J.,Ciota, A.T.,Kraiczy, P.,Kolokotronis, S.O.,Lin, Y.P.; Structural evolution of an immune evasion determinant shapes pathogen host tropism.; Proc.Natl.Acad.Sci.USA, 120:e2301549120-e2301549120, 2023; PubMed: 37364114; DOI: 10.1073/pnas.2301549120

Experimental method

X-RAY DIFFRACTION (2.59 Å)