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5ISY
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BU of 5isy by Molmil
Crystal structure of Nudix family protein with NAD
Descriptor: NADH pyrophosphatase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
Authors:Zhang, D, Guan, Z, Zou, T, Yin, P.
Deposit date:2016-03-15
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.354 Å)
Cite:Structural basis of prokaryotic NAD-RNA decapping by NudC
Cell Res., 26, 2016
7TZU
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BU of 7tzu by Molmil
Crystal structure of the E. coli thiM riboswitch bound to 1-(4-(piperazin-1-yl)pyridin-3-yl)-N-(quinoxalin-6-ylmethyl)methanamine (linked compound 38)
Descriptor: 1-[4-(piperazin-1-yl)pyridin-3-yl]-N-[(quinoxalin-6-yl)methyl]methanamine, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Nuthanakanti, A, Serganov, A.
Deposit date:2022-02-16
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:SHAPE-enabled fragment-based ligand discovery for RNA.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TZS
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BU of 7tzs by Molmil
Crystal structure of the E. coli thiM riboswitch in complex with quinoxalin-6-ylmethanamine (compound 17)
Descriptor: 1-(quinoxalin-6-yl)methanamine, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Nuthanakanti, A, Serganov, A.
Deposit date:2022-02-16
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:SHAPE-enabled fragment-based ligand discovery for RNA.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TZT
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BU of 7tzt by Molmil
Crystal structure of the E. coli thiM riboswitch in complex with N1,N1-dimethyl-N2-(quinoxalin-6-ylmethyl)ethane-1,2-diamine (linked compound 37)
Descriptor: 6-methylquinoxaline, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Nuthanakanti, A, Serganov, A.
Deposit date:2022-02-16
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:SHAPE-enabled fragment-based ligand discovery for RNA.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TZR
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BU of 7tzr by Molmil
Crystal structure of the E. coli thiM riboswitch bound to N-methyl-1-(quinoxalin-6-yl)methanamine (compound 16)
Descriptor: MAGNESIUM ION, N-methyl-1-(quinoxalin-6-yl)methanamine, POTASSIUM ION, ...
Authors:Nuthanakanti, A, Serganov, A.
Deposit date:2022-02-16
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:SHAPE-enabled fragment-based ligand discovery for RNA.
Proc.Natl.Acad.Sci.USA, 119, 2022
1A79
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BU of 1a79 by Molmil
CRYSTAL STRUCTURE OF THE TRNA SPLICING ENDONUCLEASE FROM METHANOCOCCUS JANNASCHII
Descriptor: GOLD ION, SULFATE ION, TRNA ENDONUCLEASE
Authors:Li, H, Trotta, C.R, Abelson, J.N.
Deposit date:1998-03-23
Release date:1999-06-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure and evolution of a transfer RNA splicing enzyme.
Science, 280, 1998
5JXS
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BU of 5jxs by Molmil
Mutant GC216/7AA of 3D polymerase from Foot-and-Mouth Disease Virus
Descriptor: MAGNESIUM ION, RNA Primer, RNA Template, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2016-05-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication.
J.Virol., 90, 2016
1OSW
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BU of 1osw by Molmil
The Stem of SL1 RNA in HIV-1: Structure and Nucleocapsid Protein Binding for a 1X3 Internal Loop
Descriptor: 5'-R(*GP*GP*AP*GP*GP*CP*GP*CP*UP*AP*CP*GP*GP*CP*GP*AP*GP*GP*CP*UP*CP*CP*A)-3'
Authors:Yuan, Y, Kerwood, D.J, Paoletti, A.C, Shubsda, M.F, Borer, P.N.
Deposit date:2003-03-20
Release date:2003-05-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Stem of SL1 RNA in HIV-1: Structure and Nucleocapsid Protein Binding for a 1X3 Internal Loop
Biochemistry, 42, 2003
2I82
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BU of 2i82 by Molmil
Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure
Descriptor: (5S,6R)-5-FLUORO-6-HYDROXYDIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE, 5'-R(*GP*AP*GP*GP*GP*GP*AP*UP*UP*GP*AP*AP*AP*AP*UP*CP*CP*CP*CP*UP*C)-3', Ribosomal large subunit pseudouridine synthase A
Authors:Hoang, C.
Deposit date:2006-08-31
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure
Mol.Cell, 24, 2006
7WV3
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BU of 7wv3 by Molmil
Toll-like receptor3 linear cluster
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (80-MER), ...
Authors:Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O.
Deposit date:2022-02-09
Release date:2022-11-16
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
5AXW
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BU of 5axw by Molmil
Crystal structure of Staphylococcus aureus Cas9 in complex with sgRNA and target DNA (TTGGGT PAM)
Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, DNA (28-MER), ...
Authors:Nishimasu, H, Ishitani, R, Nureki, O.
Deposit date:2015-08-01
Release date:2015-09-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Staphylococcus aureus Cas9.
Cell, 162, 2015
1L3K
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BU of 1l3k by Molmil
UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1
Descriptor: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1
Authors:Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M.
Deposit date:2002-02-27
Release date:2002-04-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1.
Nucleic Acids Res., 30, 2002
4B3Q
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BU of 4b3q by Molmil
Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface
Descriptor: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, P51 RT, PRIMER DNA, ...
Authors:Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W.
Deposit date:2012-07-25
Release date:2013-01-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (5 Å)
Cite:Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation
Nat.Struct.Mol.Biol., 20, 2013
8TJV
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BU of 8tjv by Molmil
Tetrahymena Ribozyme scaffolded Fluoride riboswitch
Descriptor: FLUORIDE ION, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Langeberg, C.J, Kieft, J.S.
Deposit date:2023-07-24
Release date:2023-11-01
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM.
Nucleic Acids Res., 51, 2023
3HKZ
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BU of 3hkz by Molmil
The X-ray crystal structure of RNA polymerase from Archaea
Descriptor: DNA-directed RNA polymerase subunit 13, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ...
Authors:Murakami, K.S.
Deposit date:2009-05-26
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The X-ray crystal structure of RNA polymerase from Archaea.
Nature, 451, 2008
7Z6K
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BU of 7z6k by Molmil
CRYSTAL STRUCTURE OF WEISSELLA VIRIDESCENS FEMXVV NON-RIBOSOMAL AMINO ACID TRANSFERASE IN COMPLEX WITH A PEPTIDYL-XNA CONJUGATE
Descriptor: 2'F-ANA (5'-D(P*(A5L)P*(CFL)P*(CFL))-R(P*(A9Z))-3'), GLYCEROL, N-acetyl-alpha-muramic acid, ...
Authors:Li de la Sierra-Gallay, I.
Deposit date:2022-03-11
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis.
Nucleic Acids Res., 50, 2022
7Z5Z
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BU of 7z5z by Molmil
CRYSTAL STRUCTURE OF WEISSELLA VIRIDESCENS FEMXVV NON-RIBOSOMAL AMINO ACID TRANSFERASE IN COMPLEX WITH A PEPTIDYL-XNA CONJUGATE
Descriptor: DNA (5'-D(P*AP*CP*C)-R(P*(A9Z))-3'), GLYCEROL, N-acetyl-alpha-muramic acid, ...
Authors:Li de la Sierra-Gallay, I.
Deposit date:2022-03-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis.
Nucleic Acids Res., 50, 2022
7JJF
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BU of 7jjf by Molmil
Sarcin-ricin loop with modified residue.
Descriptor: MAGNESIUM ION, RNA/DNA (27-mer)
Authors:Harp, J.M, Pallan, P.S, Egli, M.
Deposit date:2020-07-25
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Incorporating a Thiophosphate Modification into a Common RNA Tetraloop Motif Causes an Unanticipated Stability Boost.
Biochemistry, 59, 2020
4R3Z
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BU of 4r3z by Molmil
Crystal structure of human ArgRS-GlnRS-AIMP1 complex
Descriptor: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Arginine--tRNA ligase, cytoplasmic, ...
Authors:Fu, Y, Kim, Y, Cho, Y.
Deposit date:2014-08-18
Release date:2014-10-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (4.033 Å)
Cite:Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation
Proc.Natl.Acad.Sci.USA, 111, 2014
7L49
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BU of 7l49 by Molmil
Cryo-EM structure of CRISPR-Cas12f Ternary Complex
Descriptor: Cas12f1, NTS, Substrate, ...
Authors:Chang, L, Li, Z.
Deposit date:2020-12-18
Release date:2021-06-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for substrate recognition and cleavage by the dimerization-dependent CRISPR-Cas12f nuclease.
Nucleic Acids Res., 49, 2021
7L3R
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BU of 7l3r by Molmil
23S Sarcin Ricin Loop with a 3-deazapurine A2670
Descriptor: GLYCEROL, RNA (27-MER)
Authors:Ennifar, E, Renard, E.
Deposit date:2020-12-18
Release date:2021-05-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:Impact of 3-deazapurine nucleobases on RNA properties.
Nucleic Acids Res., 49, 2021
1FKA
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BU of 1fka by Molmil
STRUCTURE OF FUNCTIONALLY ACTIVATED SMALL RIBOSOMAL SUBUNIT AT 3.3 A RESOLUTION
Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Schluenzen, F, Tocilj, A, Zarivach, R, Harms, J, Gluehmann, M, Janell, D, Bashan, A, Bartels, H, Agmon, I, Franceschi, F, Yonath, A.
Deposit date:2000-08-09
Release date:2000-09-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution.
Cell(Cambridge,Mass.), 102, 2000
8U72
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BU of 8u72 by Molmil
Cryo-EM structure of the SPARTA oligomer with guide RNA and target DNA
Descriptor: DNA (5'-D(P*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*C)-3'), MAGNESIUM ION, Piwi domain-containing protein, ...
Authors:Malik, R, Kottur, J, Aggarwal, A.K.
Deposit date:2023-09-14
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Nucleic acid mediated activation of a short prokaryotic Argonaute immune system.
Nat Commun, 15, 2024
5W0H
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BU of 5w0h by Molmil
Structure of U2AF65 (U2AF2) RRM2 at 1.11 Angstrom Resolution
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2017-05-30
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
5W0G
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BU of 5w0g by Molmil
Structure of U2AF65 (U2AF2) RRM1 at 1.07 resolution
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, Splicing factor U2AF 65 kDa subunit, ...
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2017-05-30
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017

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数据于2024-07-10公开中

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