5AXW
Crystal structure of Staphylococcus aureus Cas9 in complex with sgRNA and target DNA (TTGGGT PAM)
Summary for 5AXW
| Entry DOI | 10.2210/pdb5axw/pdb |
| Related | 5CZZ |
| Descriptor | CRISPR-associated endonuclease Cas9, RNA (73-MER), DNA (28-MER), ... (8 entities in total) |
| Functional Keywords | crispr-cas9, genome engineering, hydrolase-rna-dna complex, hydrolase/rna/dna |
| Biological source | Staphylococcus aureus subsp. aureus More |
| Total number of polymer chains | 4 |
| Total formula weight | 159140.07 |
| Authors | Nishimasu, H.,Ishitani, R.,Nureki, O. (deposition date: 2015-08-01, release date: 2015-09-02, Last modification date: 2024-03-20) |
| Primary citation | Nishimasu, H.,Cong, L.,Yan, W.X.,Ran, F.A.,Zetsche, B.,Li, Y.,Kurabayashi, A.,Ishitani, R.,Zhang, F.,Nureki, O. Crystal Structure of Staphylococcus aureus Cas9. Cell, 162:1113-1126, 2015 Cited by PubMed: 26317473DOI: 10.1016/j.cell.2015.08.007 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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