7TZR
Crystal structure of the E. coli thiM riboswitch bound to N-methyl-1-(quinoxalin-6-yl)methanamine (compound 16)
Summary for 7TZR
| Entry DOI | 10.2210/pdb7tzr/pdb |
| Descriptor | RNA (80-MER), N-methyl-1-(quinoxalin-6-yl)methanamine, MAGNESIUM ION, ... (6 entities in total) |
| Functional Keywords | thim tpp riboswitch, rna |
| Biological source | Escherichia coli |
| Total number of polymer chains | 2 |
| Total formula weight | 52517.32 |
| Authors | Nuthanakanti, A.,Serganov, A. (deposition date: 2022-02-16, release date: 2022-05-25, Last modification date: 2023-10-18) |
| Primary citation | Zeller, M.J.,Favorov, O.,Li, K.,Nuthanakanti, A.,Hussein, D.,Michaud, A.,Lafontaine, D.A.,Busan, S.,Serganov, A.,Aube, J.,Weeks, K.M. SHAPE-enabled fragment-based ligand discovery for RNA. Proc.Natl.Acad.Sci.USA, 119:e2122660119-e2122660119, 2022 Cited by PubMed: 35561226DOI: 10.1073/pnas.2122660119 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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