8U72

Cryo-EM structure of the SPARTA oligomer with guide RNA and target DNA

Summary for 8U72

• Entry DOI: 10.2210/pdb8u72/pdb
• EMDB information: 41966
• Descriptor: RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*C)-3'), TIR domain-containing protein, ... (6 entities in total)
• Functional Keywords: rna, dna, argonaute, tir, immune system, rna binding protein-rna-dna complex, rna binding protein/rna/dna
• Biological source: Thermoflavifilum thermophilum; More
• Total number of polymer chains: 16
• Total formula weight: 528407.09

Authors

Malik, R.,Kottur, J.,Aggarwal, A.K. (deposition date: 2023-09-14, release date: 2024-06-12)

• Primary citation: Kottur, J.,Malik, R.,Aggarwal, A.K.; Nucleic acid mediated activation of prokaryotic Argonaute immune system; Nat Commun, 2024

Experimental method

ELECTRON MICROSCOPY (3.15 Å)