3RRN
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![BU of 3rrn by Molmil](/molmil-images/mine/3rrn) | S. cerevisiae dbp5 l327v bound to gle1 h337r and ip6 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | Deposit date: | 2011-04-29 | Release date: | 2011-05-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (4.001 Å) | Cite: | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export. Nature, 472, 2011
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3R24
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![BU of 3r24 by Molmil](/molmil-images/mine/3r24) | Crystal structure of nsp10/nsp16 complex of SARS coronavirus | Descriptor: | 2'-O-methyl transferase, Non-structural protein 10 and Non-structural protein 11, S-ADENOSYLMETHIONINE, ... | Authors: | Liu, X, Guo, D, Su, C, Chen, Y. | Deposit date: | 2011-03-13 | Release date: | 2011-10-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex. Plos Pathog., 7, 2011
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2AGN
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![BU of 2agn by Molmil](/molmil-images/mine/2agn) | Fitting of hepatitis C virus internal ribosome entry site domains into the 15 A Cryo-EM map of a HCV IRES-80S ribosome (H. sapiens) complex | Descriptor: | 6 nt A-RNA helix, HCV IRES DOMAIN II, HCV IRES IIIABC, ... | Authors: | Boehringer, D, Thermann, R, Ostareck-Lederer, A, Lewis, J.D, Stark, H. | Deposit date: | 2005-07-27 | Release date: | 2006-07-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (15 Å) | Cite: | Structure of the hepatitis C Virus IRES bound to the human 80S ribosome: remodeling of the HCV IRES Structure, 13, 2005
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7OXS
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![BU of 7oxs by Molmil](/molmil-images/mine/7oxs) | |
1N38
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![BU of 1n38 by Molmil](/molmil-images/mine/1n38) | reovirus polymerase lambda3 elongation complex with one phosphodiester bond formed | Descriptor: | 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 3'-DEOXY-URIDINE 5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*C)-3', ... | Authors: | Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. | Deposit date: | 2002-10-25 | Release date: | 2002-12-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3 Cell(Cambridge,Mass.), 111, 2002
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8EOS
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![BU of 8eos by Molmil](/molmil-images/mine/8eos) | M. tuberculosis RNAP elongation complex with NusG and CMPCPP | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (36-MER), DNA (38-MER), ... | Authors: | Vishwakarma, R.K, Murakami, K.S. | Deposit date: | 2022-10-04 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EXY
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![BU of 8exy by Molmil](/molmil-images/mine/8exy) | |
6WVK
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![BU of 6wvk by Molmil](/molmil-images/mine/6wvk) | Cryo-EM structure of Bacillus subtilis RNA Polymerase in complex with HelD | Descriptor: | DNA helicase IV, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Newing, T, Tolun, G, Oakley, A.J. | Deposit date: | 2020-05-06 | Release date: | 2020-11-18 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD. Nat Commun, 11, 2020
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8EOT
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![BU of 8eot by Molmil](/molmil-images/mine/8eot) | M. tuberculosis RNAP elongation complex with NusG | Descriptor: | DNA (31-MER), DNA (33-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Vishwakarma, R.K, Murakami, K.S. | Deposit date: | 2022-10-04 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase. Proc.Natl.Acad.Sci.USA, 120, 2023
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7Z0O
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![BU of 7z0o by Molmil](/molmil-images/mine/7z0o) | Structure of transcription factor UAF in complex with TBP and 35S rRNA promoter DNA | Descriptor: | Histone H3, Histone H4, Non-template DNA, ... | Authors: | Baudin, F, Murciano, B, Fung, H.K.H, Fromm, S.A, Mueller, C.W. | Deposit date: | 2022-02-23 | Release date: | 2022-04-27 | Last modified: | 2022-05-04 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanism of RNA polymerase I selection by transcription factor UAF. Sci Adv, 8, 2022
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1LUL
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![BU of 1lul by Molmil](/molmil-images/mine/1lul) | DB58, A LEGUME LECTIN FROM DOLICHOS BIFLORUS | Descriptor: | CALCIUM ION, LECTIN DB58, MANGANESE (II) ION | Authors: | Hamelryck, T.W, Bouckaert, J, Dao-Thi, M.H, Wyns, L, Etzler, M, Loris, R. | Deposit date: | 1998-06-30 | Release date: | 1998-12-30 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus. J.Mol.Biol., 286, 1999
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7VTI
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![BU of 7vti by Molmil](/molmil-images/mine/7vti) | Crystal structure of the Cas13bt3-crRNA binary complex | Descriptor: | 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ... | Authors: | Nakagawa, R, Takeda, N.S, Tomita, A, Hirano, H, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | Deposit date: | 2021-10-29 | Release date: | 2022-08-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structure and engineering of the minimal type VI CRISPR-Cas13bt3. Mol.Cell, 82, 2022
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7S37
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![BU of 7s37 by Molmil](/molmil-images/mine/7s37) | Cas9:sgRNA (S. pyogenes) in the open-protein conformation | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, Single-guide RNA | Authors: | Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A. | Deposit date: | 2021-09-04 | Release date: | 2022-04-20 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | CRISPR-Cas9 bends and twists DNA to read its sequence. Nat.Struct.Mol.Biol., 29, 2022
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7SBB
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![BU of 7sbb by Molmil](/molmil-images/mine/7sbb) | |
6H5Q
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![BU of 6h5q by Molmil](/molmil-images/mine/6h5q) | Cryo-EM structure of in vitro assembled Measles virus N into nucleocapsid-like particles (NCLPs) bound to polyA RNA hexamers. | Descriptor: | Nucleocapsid, RNA (5'-R(*AP*AP*AP*AP*AP*A)-3') | Authors: | Desfosses, A, Milles, S, Ringkjobing Jensen, M, Guseva, S, Colletier, J, Maurin, D, Schoehn, G, Gutsche, I, Ruigrok, R, Blackledge, M. | Deposit date: | 2018-07-25 | Release date: | 2019-03-13 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication. Proc.Natl.Acad.Sci.USA, 116, 2019
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6H5S
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![BU of 6h5s by Molmil](/molmil-images/mine/6h5s) | Cryo-EM map of in vitro assembled Measles virus N into nucleocapsid-like particles (NCLPs) bound to viral genomic 5-prime RNA hexamers. | Descriptor: | Nucleocapsid, RNA (5'-R(*AP*CP*CP*AP*GP*A)-3') | Authors: | Desfosses, A, Milles, S, Ringkjobing Jensen, M, Guseva, S, Colletier, J.P, Maurin, D, Schoehn, G, Gutsche, I, Ruigrok, R, Blackledge, M. | Deposit date: | 2018-07-25 | Release date: | 2019-06-12 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication. Proc.Natl.Acad.Sci.USA, 116, 2019
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7V2Z
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![BU of 7v2z by Molmil](/molmil-images/mine/7v2z) | ZIKV NS3helicase in complex with ssRNA and ATP-Mn2+ | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Core protein, MANGANESE (II) ION, ... | Authors: | Lin, M.M, Yang, H.T. | Deposit date: | 2021-08-10 | Release date: | 2022-08-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.10101676 Å) | Cite: | Structural Basis of Zika Virus Helicase in RNA Unwinding and ATP Hydrolysis. Acs Infect Dis., 8, 2022
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8W1S
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![BU of 8w1s by Molmil](/molmil-images/mine/8w1s) | Cryo-EM structure of BTV pre-core | Descriptor: | Core protein VP3, RNA-directed RNA polymerase | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | Deposit date: | 2024-02-17 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 187, 2024
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8W1R
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![BU of 8w1r by Molmil](/molmil-images/mine/8w1r) | Cryo-EM structure of BTV core | Descriptor: | Core protein VP3, RNA-directed RNA polymerase | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | Deposit date: | 2024-02-17 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 187, 2024
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7V01
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![BU of 7v01 by Molmil](/molmil-images/mine/7v01) | Staphylococcus epidermidis RP62a CRISPR short effector complex with self RNA target and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, ... | Authors: | Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A. | Deposit date: | 2022-05-09 | Release date: | 2022-07-06 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Structures of an active type III-A CRISPR effector complex. Structure, 30, 2022
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7UZX
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![BU of 7uzx by Molmil](/molmil-images/mine/7uzx) | Staphylococcus epidermidis RP62a CRISPR effector subcomplex with non-self target RNA bound | Descriptor: | CRISPR non-self RNA target, CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm4, ... | Authors: | Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A. | Deposit date: | 2022-05-09 | Release date: | 2022-07-06 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Structures of an active type III-A CRISPR effector complex. Structure, 30, 2022
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1N1H
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![BU of 1n1h by Molmil](/molmil-images/mine/1n1h) | Initiation complex of polymerase lambda3 from reovirus | Descriptor: | 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*C)-3', ... | Authors: | Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. | Deposit date: | 2002-10-17 | Release date: | 2002-12-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3 Cell(Cambridge,Mass.), 111, 2002
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7BYF
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![BU of 7byf by Molmil](/molmil-images/mine/7byf) | The crystal structure of mouse ORF10-Rae1-Nup98 complex | Descriptor: | 10 protein, MERCURY (II) ION, Peptidase S59 domain-containing protein, ... | Authors: | Gao, P, Feng, H. | Deposit date: | 2020-04-22 | Release date: | 2021-03-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10. Proc.Natl.Acad.Sci.USA, 117, 2020
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2PO1
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486D
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![BU of 486d by Molmil](/molmil-images/mine/486d) | X-RAY CRYSTAL STRUCTURES OF 70S RIBOSOME FUNCTIONAL COMPLEXES | Descriptor: | 900 STEM-LOOP OF 16S RRNA IN THE 70S RIBOSOME, A-SITE CODON OF 70S RIBOSOME, A-SITE TRNA OF 70S RIBOSOME, ... | Authors: | Cate, J.H, Yusupov, M.M, Yusupova, G.Zh, Earnest, T.N, Noller, H.F. | Deposit date: | 1999-09-09 | Release date: | 1999-10-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (7.5 Å) | Cite: | X-ray crystal structures of 70S ribosome functional complexes. Science, 285, 1999
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