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3RRN
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BU of 3rrn by Molmil
S. cerevisiae dbp5 l327v bound to gle1 h337r and ip6
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K.
Deposit date:2011-04-29
Release date:2011-05-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.001 Å)
Cite:A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature, 472, 2011
3R24
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BU of 3r24 by Molmil
Crystal structure of nsp10/nsp16 complex of SARS coronavirus
Descriptor: 2'-O-methyl transferase, Non-structural protein 10 and Non-structural protein 11, S-ADENOSYLMETHIONINE, ...
Authors:Liu, X, Guo, D, Su, C, Chen, Y.
Deposit date:2011-03-13
Release date:2011-10-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex.
Plos Pathog., 7, 2011
2AGN
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BU of 2agn by Molmil
Fitting of hepatitis C virus internal ribosome entry site domains into the 15 A Cryo-EM map of a HCV IRES-80S ribosome (H. sapiens) complex
Descriptor: 6 nt A-RNA helix, HCV IRES DOMAIN II, HCV IRES IIIABC, ...
Authors:Boehringer, D, Thermann, R, Ostareck-Lederer, A, Lewis, J.D, Stark, H.
Deposit date:2005-07-27
Release date:2006-07-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Structure of the hepatitis C Virus IRES bound to the human 80S ribosome: remodeling of the HCV IRES
Structure, 13, 2005
7OXS
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BU of 7oxs by Molmil
1.91 A crystal structure of DNA/2'-O-methyl-RNA heteroduplex
Descriptor: DNA (5'-D(*GP*TP*CP*TP*CP*CP*TP*AP*G)-3'), RNA (5'-R(*(OMC)P*(OMU)P*(A2M)P*(OMG)P*(OMG)P*(A2M)P*(OMG)P*(A2M)P*(OMC))-3'), SULFATE ION
Authors:Dolot, R.M, Maciaszek, A, Nawrot, B.C.
Deposit date:2021-06-23
Release date:2021-07-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:First High-Resolution Crystal Structures of DNA:2'-O-Methyl-RNA Heteroduplexes
Crystals, 2022
1N38
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BU of 1n38 by Molmil
reovirus polymerase lambda3 elongation complex with one phosphodiester bond formed
Descriptor: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 3'-DEOXY-URIDINE 5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*C)-3', ...
Authors:Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C.
Deposit date:2002-10-25
Release date:2002-12-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3
Cell(Cambridge,Mass.), 111, 2002
8EOS
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BU of 8eos by Molmil
M. tuberculosis RNAP elongation complex with NusG and CMPCPP
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (36-MER), DNA (38-MER), ...
Authors:Vishwakarma, R.K, Murakami, K.S.
Deposit date:2022-10-04
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EXY
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BU of 8exy by Molmil
M. tuberculosis RNAP paused complex with B. subtilis NusG and GMPCPP
Descriptor: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Vishwakarma, R.K, Murakami, K.S.
Deposit date:2022-10-26
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase.
Proc.Natl.Acad.Sci.USA, 120, 2023
6WVK
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BU of 6wvk by Molmil
Cryo-EM structure of Bacillus subtilis RNA Polymerase in complex with HelD
Descriptor: DNA helicase IV, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Newing, T, Tolun, G, Oakley, A.J.
Deposit date:2020-05-06
Release date:2020-11-18
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD.
Nat Commun, 11, 2020
8EOT
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BU of 8eot by Molmil
M. tuberculosis RNAP elongation complex with NusG
Descriptor: DNA (31-MER), DNA (33-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Vishwakarma, R.K, Murakami, K.S.
Deposit date:2022-10-04
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase.
Proc.Natl.Acad.Sci.USA, 120, 2023
7Z0O
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BU of 7z0o by Molmil
Structure of transcription factor UAF in complex with TBP and 35S rRNA promoter DNA
Descriptor: Histone H3, Histone H4, Non-template DNA, ...
Authors:Baudin, F, Murciano, B, Fung, H.K.H, Fromm, S.A, Mueller, C.W.
Deposit date:2022-02-23
Release date:2022-04-27
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of RNA polymerase I selection by transcription factor UAF.
Sci Adv, 8, 2022
1LUL
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BU of 1lul by Molmil
DB58, A LEGUME LECTIN FROM DOLICHOS BIFLORUS
Descriptor: CALCIUM ION, LECTIN DB58, MANGANESE (II) ION
Authors:Hamelryck, T.W, Bouckaert, J, Dao-Thi, M.H, Wyns, L, Etzler, M, Loris, R.
Deposit date:1998-06-30
Release date:1998-12-30
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus.
J.Mol.Biol., 286, 1999
7VTI
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BU of 7vti by Molmil
Crystal structure of the Cas13bt3-crRNA binary complex
Descriptor: 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ...
Authors:Nakagawa, R, Takeda, N.S, Tomita, A, Hirano, H, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O.
Deposit date:2021-10-29
Release date:2022-08-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure and engineering of the minimal type VI CRISPR-Cas13bt3.
Mol.Cell, 82, 2022
7S37
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BU of 7s37 by Molmil
Cas9:sgRNA (S. pyogenes) in the open-protein conformation
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Single-guide RNA
Authors:Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
Deposit date:2021-09-04
Release date:2022-04-20
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
7SBB
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BU of 7sbb by Molmil
Structure of type I-D Cascade bound to a ssRNA target
Descriptor: Cas10d, Cas11d, Cas5d, ...
Authors:Schwartz, E.A, Taylor, D.W.
Deposit date:2021-09-24
Release date:2022-06-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural rearrangements allow nucleic acid discrimination by type I-D Cascade.
Nat Commun, 13, 2022
6H5Q
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BU of 6h5q by Molmil
Cryo-EM structure of in vitro assembled Measles virus N into nucleocapsid-like particles (NCLPs) bound to polyA RNA hexamers.
Descriptor: Nucleocapsid, RNA (5'-R(*AP*AP*AP*AP*AP*A)-3')
Authors:Desfosses, A, Milles, S, Ringkjobing Jensen, M, Guseva, S, Colletier, J, Maurin, D, Schoehn, G, Gutsche, I, Ruigrok, R, Blackledge, M.
Deposit date:2018-07-25
Release date:2019-03-13
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication.
Proc.Natl.Acad.Sci.USA, 116, 2019
6H5S
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BU of 6h5s by Molmil
Cryo-EM map of in vitro assembled Measles virus N into nucleocapsid-like particles (NCLPs) bound to viral genomic 5-prime RNA hexamers.
Descriptor: Nucleocapsid, RNA (5'-R(*AP*CP*CP*AP*GP*A)-3')
Authors:Desfosses, A, Milles, S, Ringkjobing Jensen, M, Guseva, S, Colletier, J.P, Maurin, D, Schoehn, G, Gutsche, I, Ruigrok, R, Blackledge, M.
Deposit date:2018-07-25
Release date:2019-06-12
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication.
Proc.Natl.Acad.Sci.USA, 116, 2019
7V2Z
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BU of 7v2z by Molmil
ZIKV NS3helicase in complex with ssRNA and ATP-Mn2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Core protein, MANGANESE (II) ION, ...
Authors:Lin, M.M, Yang, H.T.
Deposit date:2021-08-10
Release date:2022-08-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.10101676 Å)
Cite:Structural Basis of Zika Virus Helicase in RNA Unwinding and ATP Hydrolysis.
Acs Infect Dis., 8, 2022
8W1S
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BU of 8w1s by Molmil
Cryo-EM structure of BTV pre-core
Descriptor: Core protein VP3, RNA-directed RNA polymerase
Authors:Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H.
Deposit date:2024-02-17
Release date:2024-04-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
8W1R
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BU of 8w1r by Molmil
Cryo-EM structure of BTV core
Descriptor: Core protein VP3, RNA-directed RNA polymerase
Authors:Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H.
Deposit date:2024-02-17
Release date:2024-04-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
7V01
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BU of 7v01 by Molmil
Staphylococcus epidermidis RP62a CRISPR short effector complex with self RNA target and ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, ...
Authors:Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A.
Deposit date:2022-05-09
Release date:2022-07-06
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structures of an active type III-A CRISPR effector complex.
Structure, 30, 2022
7UZX
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BU of 7uzx by Molmil
Staphylococcus epidermidis RP62a CRISPR effector subcomplex with non-self target RNA bound
Descriptor: CRISPR non-self RNA target, CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm4, ...
Authors:Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A.
Deposit date:2022-05-09
Release date:2022-07-06
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Structures of an active type III-A CRISPR effector complex.
Structure, 30, 2022
1N1H
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BU of 1n1h by Molmil
Initiation complex of polymerase lambda3 from reovirus
Descriptor: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*C)-3', ...
Authors:Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C.
Deposit date:2002-10-17
Release date:2002-12-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3
Cell(Cambridge,Mass.), 111, 2002
7BYF
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BU of 7byf by Molmil
The crystal structure of mouse ORF10-Rae1-Nup98 complex
Descriptor: 10 protein, MERCURY (II) ION, Peptidase S59 domain-containing protein, ...
Authors:Gao, P, Feng, H.
Deposit date:2020-04-22
Release date:2021-03-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10.
Proc.Natl.Acad.Sci.USA, 117, 2020
2PO1
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BU of 2po1 by Molmil
Crystal structure of the P. abyssi exosome RNase PH ring complexed with a single stranded 10-mer poly(A) RNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 10-mer poly(A), Probable exosome complex exonuclease 1, ...
Authors:Navarro, M.V.A.S, Guimaraes, B.G.
Deposit date:2007-04-25
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Insights into the mechanism of progressive RNA degradation by the archaeal exosome.
J.Biol.Chem., 283, 2008
486D
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BU of 486d by Molmil
X-RAY CRYSTAL STRUCTURES OF 70S RIBOSOME FUNCTIONAL COMPLEXES
Descriptor: 900 STEM-LOOP OF 16S RRNA IN THE 70S RIBOSOME, A-SITE CODON OF 70S RIBOSOME, A-SITE TRNA OF 70S RIBOSOME, ...
Authors:Cate, J.H, Yusupov, M.M, Yusupova, G.Zh, Earnest, T.N, Noller, H.F.
Deposit date:1999-09-09
Release date:1999-10-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (7.5 Å)
Cite:X-ray crystal structures of 70S ribosome functional complexes.
Science, 285, 1999

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数据于2024-07-10公开中

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