5W2O
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![BU of 5w2o by Molmil](/molmil-images/mine/5w2o) | Crystal structure of Mycobacterium tuberculosis KasA | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 1, CHLORIDE ION, ... | Authors: | Capodagli, G.C, Neiditch, M.B. | Deposit date: | 2017-06-06 | Release date: | 2018-12-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA. MBio, 9, 2018
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5W2Q
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![BU of 5w2q by Molmil](/molmil-images/mine/5w2q) | Crystal structure of Mycobacterium tuberculosis KasA in complex with 6U5 | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 1, GLYCEROL, ... | Authors: | Capodagli, G.C, Neiditch, M.B. | Deposit date: | 2017-06-06 | Release date: | 2018-12-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA. MBio, 9, 2018
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5W2P
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![BU of 5w2p by Molmil](/molmil-images/mine/5w2p) | Crystal structure of Mycobacterium tuberculosis KasA in complex with 6U5 | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 1, GLYCEROL, ... | Authors: | Capodagli, G.C, Neiditch, M.B. | Deposit date: | 2017-06-06 | Release date: | 2018-12-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA. MBio, 9, 2018
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2FNQ
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![BU of 2fnq by Molmil](/molmil-images/mine/2fnq) | |
2GFX
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![BU of 2gfx by Molmil](/molmil-images/mine/2gfx) | |
6HXQ
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![BU of 6hxq by Molmil](/molmil-images/mine/6hxq) | |
7K73
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![BU of 7k73 by Molmil](/molmil-images/mine/7k73) | |
2GFV
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![BU of 2gfv by Molmil](/molmil-images/mine/2gfv) | |
2WDY
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![BU of 2wdy by Molmil](/molmil-images/mine/2wdy) | Crystal structure of the Streptomyces coelicolor D111A AcpS mutant in complex with cofactor CoA at 1.4 A | Descriptor: | COENZYME A, HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE, MAGNESIUM ION, ... | Authors: | Dall'Aglio, P, Arthur, C, Crump, M.P, Crosby, J, Hadfield, A.T. | Deposit date: | 2009-03-27 | Release date: | 2010-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Analysis of Streptomyces Coelicolor Phosphopantetheinyl Transferase, Acps, Reveals the Basis for Relaxed Substrate Specificity. Biochemistry, 50, 2011
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3IL9
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![BU of 3il9 by Molmil](/molmil-images/mine/3il9) | Structure of E. coli FabH | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | Authors: | Gajiwala, K.S, Margosiak, S, Lu, J, Cortez, J, Su, Y, Nie, Z, Appelt, K. | Deposit date: | 2009-08-06 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme. Febs Lett., 583, 2009
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4LS8
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![BU of 4ls8 by Molmil](/molmil-images/mine/4ls8) | Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a covalent complex with cerulenin | Descriptor: | (3R,7E,10E)-3-hydroxy-4-oxododeca-7,10-dienamide, 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase 2, ... | Authors: | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | Deposit date: | 2013-07-22 | Release date: | 2014-04-02 | Last modified: | 2014-06-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into bacterial resistance to cerulenin. Febs J., 281, 2014
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4LS6
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![BU of 4ls6 by Molmil](/molmil-images/mine/4ls6) | Crystal structure of beta-ketoacyl-ACP synthase II (FabF) I108F mutant from Bacillus subtilis | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, CHLORIDE ION, GLYCEROL, ... | Authors: | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | Deposit date: | 2013-07-22 | Release date: | 2014-04-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Structural insights into bacterial resistance to cerulenin. Febs J., 281, 2014
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4LS5
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![BU of 4ls5 by Molmil](/molmil-images/mine/4ls5) | |
4RRX
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![BU of 4rrx by Molmil](/molmil-images/mine/4rrx) | Crystal Structure of Apo Murine V89W Cyclooxygenase-2 Complexed with Lumiracoxib | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Prostaglandin G/H synthase 2, ... | Authors: | Xu, S, Blobaum, A.L, Banerjee, S, Marnett, L.J. | Deposit date: | 2014-11-06 | Release date: | 2015-04-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Action at a Distance: MUTATIONS OF PERIPHERAL RESIDUES TRANSFORM RAPID REVERSIBLE INHIBITORS TO SLOW, TIGHT BINDERS OF CYCLOOXYGENASE-2. J.Biol.Chem., 290, 2015
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4RS0
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![BU of 4rs0 by Molmil](/molmil-images/mine/4rs0) | Crystal Structure of Murine H90W Cyclooxygenase-2 Complexed with S-ibuprofen | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IBUPROFEN, ... | Authors: | Xu, S, Blobaum, A.L, Banerjee, S, Marnett, L.J. | Deposit date: | 2014-11-06 | Release date: | 2015-04-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.807 Å) | Cite: | Action at a Distance: MUTATIONS OF PERIPHERAL RESIDUES TRANSFORM RAPID REVERSIBLE INHIBITORS TO SLOW, TIGHT BINDERS OF CYCLOOXYGENASE-2. J.Biol.Chem., 290, 2015
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4RRW
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![BU of 4rrw by Molmil](/molmil-images/mine/4rrw) | Crystal Structure of Apo Murine Cyclooxygenase-2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Prostaglandin G/H synthase 2, ... | Authors: | Xu, S, Blobaum, A.L, Banerjee, S, Marnett, L.J. | Deposit date: | 2014-11-06 | Release date: | 2015-04-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.569 Å) | Cite: | Action at a Distance: MUTATIONS OF PERIPHERAL RESIDUES TRANSFORM RAPID REVERSIBLE INHIBITORS TO SLOW, TIGHT BINDERS OF CYCLOOXYGENASE-2. J.Biol.Chem., 290, 2015
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4RRZ
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![BU of 4rrz by Molmil](/molmil-images/mine/4rrz) | Crystal Structure of Apo Murine H90W Cyclooxygenase-2 Complexed with Lumiracoxib | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Prostaglandin G/H synthase 2, ... | Authors: | Xu, S, Blobaum, A.L, Banerjee, S, Marnett, L.J. | Deposit date: | 2014-11-06 | Release date: | 2015-04-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.569 Å) | Cite: | Action at a Distance: MUTATIONS OF PERIPHERAL RESIDUES TRANSFORM RAPID REVERSIBLE INHIBITORS TO SLOW, TIGHT BINDERS OF CYCLOOXYGENASE-2. J.Biol.Chem., 290, 2015
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7LLA
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![BU of 7lla by Molmil](/molmil-images/mine/7lla) | |
3IL7
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![BU of 3il7 by Molmil](/molmil-images/mine/3il7) | Crystal structure of S. aureus FabH | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | Authors: | Gajiwala, K.S, Margosiak, S, Lu, J, Cortez, J, Su, Y, Nie, Z, Appelt, K. | Deposit date: | 2009-08-06 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme. Febs Lett., 583, 2009
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7LJ9
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![BU of 7lj9 by Molmil](/molmil-images/mine/7lj9) | |
3IL3
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![BU of 3il3 by Molmil](/molmil-images/mine/3il3) | Structure of Haemophilus influenzae FabH | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | Authors: | Gajiwala, K.S, Margosiak, S, Lu, J, Cortez, J, Su, Y, Nie, Z, Appelt, K. | Deposit date: | 2009-08-06 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme. Febs Lett., 583, 2009
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3IL4
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![BU of 3il4 by Molmil](/molmil-images/mine/3il4) | Structure of E. faecalis FabH in complex with acetyl CoA | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 3, ACETYL COENZYME *A | Authors: | Gajiwala, K.S, Margosiak, S, Lu, J, Cortez, J, Su, Y, Nie, Z, Appelt, K. | Deposit date: | 2009-08-06 | Release date: | 2009-08-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme. Febs Lett., 583, 2009
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4LS7
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![BU of 4ls7 by Molmil](/molmil-images/mine/4ls7) | Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a non-covalent complex with cerulenin | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, Cerulenin, GLYCEROL, ... | Authors: | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | Deposit date: | 2013-07-22 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.674 Å) | Cite: | Structural insights into bacterial resistance to cerulenin. Febs J., 281, 2014
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6HXN
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![BU of 6hxn by Molmil](/molmil-images/mine/6hxn) | |
3DY5
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![BU of 3dy5 by Molmil](/molmil-images/mine/3dy5) | Allene oxide synthase 8R-lipoxygenase from Plexaura homomalla | Descriptor: | Allene oxide synthase-lipoxygenase protein, FE (II) ION, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gilbert, N.C, Niebuhr, M, Tsuruta, H, Newcomer, M.E. | Deposit date: | 2008-07-25 | Release date: | 2008-10-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.51 Å) | Cite: | A covalent linker allows for membrane targeting of an oxylipin biosynthetic complex. Biochemistry, 47, 2008
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