PDB: 7770 resultsInfo pagesStatus searchChemie searchBIRD

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3IDO	Crystal structure of protein tyrosine phosphatase from Entamoeba histolytica with a phosphotyrosine crude mimic HEPES molecule in the active site Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Protein tyrosine phosphatase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2009-07-21 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphatase. Mol.Biochem.Parasitol., 193, 2014
2ZZ0	Crystal structure of human thioredoxin reductase I (SeCys 498 Cys) Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, Thioredoxin reductase 1, ... Authors: Lo, Y.C, Ko, T.P, Wang, A.H.J. Deposit date: 2009-02-02 Release date: 2009-08-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Terpyridine-platinum(II) complexes are effective inhibitors of mammalian topoisomerases and human thioredoxin reductase 1. J.Inorg.Biochem., 103, 2009
2ZZB	Crystal structure of human thioredoxin reductase I and terpyridine platinum(II) Descriptor: 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... Authors: Lo, Y.C, Ko, T.P, Wang, A.H.J. Deposit date: 2009-02-09 Release date: 2009-08-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Terpyridine-platinum(II) complexes are effective inhibitors of mammalian topoisomerases and human thioredoxin reductase 1. J.Inorg.Biochem., 103, 2009
3II4	Structure of mycobacterial lipoamide dehydrogenase bound to a triazaspirodimethoxybenzoyl inhibitor Descriptor: Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, N-[2-(2,4-dichlorophenyl)ethyl]-2-{8-[(2,4-dimethoxyphenyl)carbonyl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl}acetamide Authors: Lima, C.D. Deposit date: 2009-07-31 Release date: 2010-01-26 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase . Biochemistry, 49, 2010
3A3O	Crystal structure of complex between SA-subtilisin and Tk-propeptide with deletion of the five C-terminal residues Descriptor: CALCIUM ION, Tk-subtilisin, ZINC ION Authors: Tanaka, S, Matsumura, H, Koga, Y, Takano, K, Kanaya, S. Deposit date: 2009-06-15 Release date: 2009-08-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Identification of the interactions critical for propeptide-catalyzed folding of Tk-subtilisin J.Mol.Biol., 394, 2009
3A29	Crystal structure of human liver FBPase in complex with tricyclic inhibitor Descriptor: 2-amino-4,5-dihydronaphtho[1,2-d][1,3]thiazol-8-yl dihydrogen phosphate, Fructose-1,6-bisphosphatase 1 Authors: Takahashi, M, Sone, J, Hanzawa, H. Deposit date: 2009-05-08 Release date: 2009-10-06 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Synthesis, SAR, and X-ray structure of tricyclic compounds as potent FBPase inhibitors Bioorg.Med.Chem.Lett., 19, 2009
2J25	Partially deglycosylated glucoceramidase Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUCOSYLCERAMIDASE, ... Authors: Brumshtein, B, Wormald, M.R, Silman, I, Futerman, A.H, Sussman, J.L. Deposit date: 2006-08-16 Release date: 2006-12-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural Comparison of Differently Glycosylated Forms of Acid-Beta-Glucosidase, the Defective Enzyme in Gaucher Disease Acta Crystallogr.,Sect.D, 62, 2006
3I78	35/99/170/186/220-loops of FXa in SGT Descriptor: BENZAMIDINE, SODIUM ION, SULFATE ION, ... Authors: Page, M.J, Di Cera, E. Deposit date: 2009-07-08 Release date: 2010-06-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3 Å) Cite: Combinatorial Enzyme Design Probes Allostery and Cooperativity in the Trypsin Fold. J.Mol.Biol., 399, 2010
3A2C	Crystal structure of a pyrazolopyrimidine inhibitor complex bound to MAPKAP Kinase-2 (MK2) Descriptor: MAP kinase-activated protein kinase 2, N~7~-(4-ethoxyphenyl)-6-methyl-N~5~-[(3S)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine, SULFATE ION Authors: Fujino, A, Takimoto-Kamimura, M. Deposit date: 2009-05-12 Release date: 2010-05-12 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural analysis of an MK2-inhibitor complex: insight into the regulation of the secondary structure of the Gly-rich loop by TEI-I01800 Acta Crystallogr.,Sect.D, 66, 2010
2SGE	GLU 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7 Descriptor: Ovomucoid, PHOSPHATE ION, POTASSIUM ION, ... Authors: Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G. Deposit date: 1999-03-25 Release date: 2003-08-26 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B. Protein Sci., 4, 1995
305D	SIDE-BY-SIDE BINDING OF DISTAMYCIN MOLECULES TO D(ICATATIC) IN THE TETRAGONAL FORM Descriptor: DISTAMYCIN A, DNA (5'-D(*IP*CP*AP*TP*AP*TP*IP*C)-3'), MAGNESIUM ION Authors: Chen, X, Ramakrishnan, B, Sundaralingam, M. Deposit date: 1997-01-03 Release date: 1997-09-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Crystal structures of the side-by-side binding of distamycin to AT-containing DNA octamers d(ICITACIC) and d(ICATATIC). J.Mol.Biol., 267, 1997
3A59	Structure of Hemoglobin from flightless bird (Struthio camelus) Descriptor: Hemoglobin subunit alpha-A, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE Authors: Jaimohan, S.M, Naresh, M.D, Mandal, A.B. Deposit date: 2009-08-03 Release date: 2009-08-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.41 Å) Cite: Structure of Hemoglobin from flightless bird (Struthio camelus) to be published
3IEZ	Crystal structure of the RasGAP C-terminal (RGC) domain of IQGAP2 Descriptor: Ras GTPase-activating-like protein IQGAP2, UNKNOWN ATOM OR ION Authors: Nedyalkova, L, Tempel, W, Tong, Y, Zhong, N, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) Deposit date: 2009-07-23 Release date: 2009-11-03 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of the RasGAP C-terminal (RGC) domain of IQGAP2 To be Published
3A7W	Crystal Structure of Trypsin complexed with (E)-4-((tetrahydro-2H-pyran-2-yloxyimino)methyl)benzimidamide (soaking 4hours) Descriptor: (E)-4-((tetrahydro-2H-pyran-2-yloxyimino)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A88	Crystal Structure of Trypsin complexed with (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide (soaking 30 minutes) Descriptor: (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3ITP	Crystal structure of Staphylococcal nuclease variant Delta+PHS F34K at cryogenic temperature Descriptor: CALCIUM ION, Nuclease A, THYMIDINE-3',5'-DIPHOSPHATE Authors: Khangulov, V.S, Schlessman, J.L, Heroux, A, Garcia-Moreno, E.B. Deposit date: 2009-08-28 Release date: 2010-07-21 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal structure of Staphylococcal nuclease variant Delta+PHS F34K at cryogenic temperature To be Published
2RNM	Structure of The HET-s(218-289) prion in its amyloid form obtained by solid-state NMR Descriptor: Small s protein Authors: Wasmer, C, Lange, A, Van Melckebeke, H, Siemer, A, Riek, R, Meier, B.H. Deposit date: 2008-01-24 Release date: 2008-04-01 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core Science, 319, 2008
2RFX	Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... Authors: Archbold, J.K, Macdonald, W.A, Rossjohn, J, McCluskey, J. Deposit date: 2007-10-02 Release date: 2008-07-08 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity Immunity, 28, 2008
2HK4	Dimeric solution structure of the cyclic octamer d(CCGTCCGT) Descriptor: 5'-D(P*CP*CP*GP*TP*CP*CP*GP*T)-3' Authors: Escaja, N, Gomez-Pinto, I, Pedroso, E, Gonzalez, C. Deposit date: 2006-07-03 Release date: 2007-03-20 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Four-stranded DNA structures can be stabilized by two different types of minor groove G:C:G:C tetrads. J.Am.Chem.Soc., 129, 2007
3A1J	Crystal structure of the human Rad9-Hus1-Rad1 complex Descriptor: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1, ... Authors: Sohn, S.Y, Cho, Y. Deposit date: 2009-04-08 Release date: 2009-06-02 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structure of the Human Rad9-Hus1-Rad1 Clamp J.Mol.Biol., 390, 2009
306D	SIDE-BY-SIDE BINDING OF DISTAMYCIN MOLECULES TO D(ICITACIC) Descriptor: DISTAMYCIN A, DNA (5'-D(*IP*CP*IP*TP*AP*CP*IP*C)-3'), MAGNESIUM ION Authors: Chen, X, Ramakrishnan, B, Sundaralingam, M. Deposit date: 1997-01-03 Release date: 1997-09-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structures of the side-by-side binding of distamycin to AT-containing DNA octamers d(ICITACIC) and d(ICATATIC). J.Mol.Biol., 267, 1997
3IMD	Crystal Structure of the Grb2 SH2 Domain in Complex with a Flexible Ac-pY-Q-N-NH2 Tripeptide Mimic Descriptor: CHLORIDE ION, Growth factor receptor-bound protein 2, MAGNESIUM ION, ... Authors: Clements, J.H. Deposit date: 2009-08-10 Release date: 2009-11-17 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization. J.Am.Chem.Soc., 131, 2009
3A7V	Crystal Structure of Trypsin complexed with 3-formylbenzimidamide Descriptor: 3-formylbenzenecarboximidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A87	Crystal Structure of Trypsin complexed with (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide (soaking 5 minutes) Descriptor: (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
2SGF	PHE 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B Descriptor: Ovomucoid, PHOSPHATE ION, Streptogrisin B Authors: Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G. Deposit date: 1999-03-25 Release date: 2003-08-26 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs To be Published

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