1YVX
 
 | | Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor | | Descriptor: | 3-[ISOPROPYL(4-METHYLBENZOYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION | | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. | | Deposit date: | 2005-02-16 | | Release date: | 2005-03-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.
J.Biol.Chem., 280, 2005
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1YVZ
 | | Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor | | Descriptor: | 3-[(2,4-DICHLOROBENZOYL)(ISOPROPYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION | | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. | | Deposit date: | 2005-02-16 | | Release date: | 2005-03-22 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.
J.Biol.Chem., 280, 2005
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3P8B
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2XI5
 | | N-terminal endonuclease domain of La Crosse virus L-protein | | Descriptor: | MANGANESE (II) ION, RNA POLYMERASE L | | Authors: | Reguera, J, Weber, F, Cusack, S. | | Deposit date: | 2010-06-28 | | Release date: | 2010-10-06 | | Last modified: | 2012-07-18 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription.
Plos Pathog., 6, 2010
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2XI7
 | | N-terminal endonuclease domain of La Crosse virus L-protein | | Descriptor: | 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, RNA POLYMERASE L | | Authors: | Reguera, J, Weber, F, Cusack, S. | | Deposit date: | 2010-06-28 | | Release date: | 2010-10-06 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription.
Plos Pathog., 6, 2010
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2CKZ
 | | X-ray structure of RNA polymerase III subcomplex C17-C25. | | Descriptor: | DNA-DIRECTED RNA POLYMERASE III 18 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE III 25 KD POLYPEPTIDE | | Authors: | Jasiak, A.J, Armache, K.-J, Martens, B, Jansen, R.-P, Cramer, P. | | Deposit date: | 2006-04-24 | | Release date: | 2006-07-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural Biology of RNA Polymerase III: Subcomplex C17/-C25 X-Ray Structure and 11-Subunit Enzyme Model
Mol.Cell, 23, 2006
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1S0V
 | | Structural basis for substrate selection by T7 RNA polymerase | | Descriptor: | 5'-D(*G*GP*GP*AP*AP*TP*CP*GP*AP*TP*AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*C)-3', 5'-R(*AP*AP*CP*U*GP*CP*GP*GP*CP*GP*AP*U)-3', ... | | Authors: | Temiakov, D, Patlan, V, Anikin, M, McAllister, W.T, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-01-05 | | Release date: | 2004-02-24 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis for substrate selection by t7 RNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
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7VW5
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3OMX
 | | Crystal structure of Ssu72 with vanadate complex | | Descriptor: | CG14216, VANADATE ION | | Authors: | Zhang, Y, Zhang, M, Zhang, Y. | | Deposit date: | 2010-08-27 | | Release date: | 2011-01-19 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.3366 Å) | | Cite: | Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue.
Biochem.J., 434, 2011
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7JV7
 | | Crystal Structure of the yeast RNA Pol II CTD kinase CTDK-1 complex | | Descriptor: | CITRATE ANION, CTD kinase subunit alpha, CTD kinase subunit beta, ... | | Authors: | Xie, Y, Ren, Y. | | Deposit date: | 2020-08-20 | | Release date: | 2021-01-27 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.850553 Å) | | Cite: | Structure and activation mechanism of the yeast RNA Pol II CTD kinase CTDK-1 complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
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2XP1
 | | Structure of the tandem SH2 domains from Antonospora locustae transcription elongation factor Spt6 | | Descriptor: | CHLORIDE ION, SPT6, SULFATE ION | | Authors: | Diebold, M.-L, Koch, M, Cavarelli, J, Romier, C. | | Deposit date: | 2010-08-24 | | Release date: | 2010-09-29 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Noncanonical Tandem Sh2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II.
J.Biol.Chem., 285, 2010
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2PA8
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5CE7
 | | Structure of a non-canonical CID of Ctk3 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CTD kinase subunit gamma | | Authors: | Muehlbacher, W, Mayer, A, Sun, M, Remmert, M, Cheung, A.C, Niesser, J, Soeding, J, Cramer, P. | | Deposit date: | 2015-07-06 | | Release date: | 2015-08-05 | | Last modified: | 2015-09-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a noncanonical CTD-interacting domain fold.
Proteins, 83, 2015
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5IEM
 | | NMR structure of the 5'-terminal hairpin of the 7SK snRNA | | Descriptor: | 7SK snRNA | | Authors: | Bourbigot, S, Dock-Bregeon, A.C, Coutant, J, Kieffer, B, Lebars, I. | | Deposit date: | 2016-02-25 | | Release date: | 2016-11-02 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 5'-terminal hairpin of the 7SK small nuclear RNA.
RNA, 22, 2016
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5HCI
 | | GPN-loop GTPase Npa3 in complex with GDP | | Descriptor: | GLYCEROL, GPN-loop GTPase 1, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. | | Deposit date: | 2016-01-04 | | Release date: | 2016-01-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly.
Mol.Cell.Biol., 36, 2015
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5HCN
 | | GPN-loop GTPase Npa3 in complex with GMPPCP | | Descriptor: | GLYCEROL, GPN-loop GTPase 1, LAURIC ACID, ... | | Authors: | Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. | | Deposit date: | 2016-01-04 | | Release date: | 2016-01-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly.
Mol.Cell.Biol., 36, 2015
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3JB7
 | | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus | | Descriptor: | CPV RNA-dependent RNA polymerase, CYTIDINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H. | | Deposit date: | 2015-08-03 | | Release date: | 2015-10-28 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
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3JB6
 | | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase, VP1 CSP, ... | | Authors: | Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H. | | Deposit date: | 2015-08-02 | | Release date: | 2015-10-28 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
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3FDF
 | | Crystal structure of the serine phosphatase of RNA polymerase II CTD (SSU72 superfamily) from Drosophila melanogaster. Orthorhombic crystal form. Northeast Structural Genomics Consortium target FR253. | | Descriptor: | FR253 | | Authors: | Kuzin, A.P, Chen, Y, Seetharaman, J, Forouhar, F, Chinag, Y, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-11-25 | | Release date: | 2009-01-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Orthorombic crystal structure of serine phosphatase of rna polymerase ii ctd from fly drosofila melanogaster. northeast structural genomics consortium target fr253.
To be Published
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4FF3
 | | N4 mini-vRNAP transcription initiation complex, 3 min after soaking GTP, ATP and Mn | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Bacteriophage N4 P2 promoter, GUANOSINE-5'-MONOPHOSPHATE, ... | | Authors: | Murakami, K.S, Basu, R.S. | | Deposit date: | 2012-05-30 | | Release date: | 2012-12-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.997 Å) | | Cite: | Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray Crystallography.
J.Biol.Chem., 288, 2013
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4FF2
 | | N4 mini-vRNAP transcription initiation complex, 2 min after soaking GTP, ATP and Mn | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Bacteriophage N4 P2 promoter, GUANOSINE-5'-MONOPHOSPHATE, ... | | Authors: | Murakami, K.S, Basu, R.S. | | Deposit date: | 2012-05-30 | | Release date: | 2012-12-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray Crystallography.
J.Biol.Chem., 288, 2013
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4FF4
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4BK0
 | | Crystal structure of the KIX domain of human RECQL5 (domain-swapped dimer) | | Descriptor: | ATP-DEPENDENT DNA HELICASE Q5, DI(HYDROXYETHYL)ETHER | | Authors: | Kassube, S.A, Jinek, M, Fang, J, Tsutakawa, S, Nogales, E. | | Deposit date: | 2013-04-21 | | Release date: | 2013-06-12 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Mimicry in Transcription Regulation of Human RNA Polymerase II by the DNA Helicase Recql5
Nat.Struct.Mol.Biol., 20, 2013
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2KM4
 | | Solution structure of Rtt103 CTD interacting domain | | Descriptor: | Regulator of Ty1 transposition protein 103 | | Authors: | Lunde, B.M, Reichow, S, Kim, M, Leeper, T.C, Becker, R, Buratowski, S, Meinhart, A, Varani, G. | | Deposit date: | 2009-07-20 | | Release date: | 2010-09-08 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.
Nat.Struct.Mol.Biol., 17, 2010
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4M3O
 | | Crystal structure of K.lactis Rtr1 NTD | | Descriptor: | KLLA0F12672p, ZINC ION | | Authors: | Hsu, P.L, Yang, W, Zheng, N, Varani, G. | | Deposit date: | 2013-08-06 | | Release date: | 2014-07-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Rtr1 Is a Dual Specificity Phosphatase That Dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD.
J.Mol.Biol., 426, 2014
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