PDB: 909 resultsInfo pagesStatus searchChemie searchBIRD

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8ESR	Ytm1 associated nascent 60S ribosome (-fkbp39) State 2 Descriptor: 25S rRNA (cytosine-C(5))-methyltransferase nop2, 60S ribosomal protein L13, 60S ribosomal protein L14, ... Authors: Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. Deposit date: 2022-10-14 Release date: 2022-11-30 Last modified: 2022-12-14 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
8EUP	Ytm1 associated 60S nascent ribosome State 1A Descriptor: 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... Authors: Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. Deposit date: 2022-10-19 Release date: 2022-11-30 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
8EV3	Ytm1 associated 60S nascent ribosome (-Fkbp39) State 1B Descriptor: 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... Authors: Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. Deposit date: 2022-10-19 Release date: 2022-11-30 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3 Å) Cite: Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
5TF6	Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core Descriptor: CHLORIDE ION, GLYCEROL, POTASSIUM ION, ... Authors: Montemayor, E.J, Brow, D.A, Butcher, S.E. Deposit date: 2016-09-24 Release date: 2017-01-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core. Acta Crystallogr D Struct Biol, 73, 2017
5IFM	Human NONO (p54nrb) Homodimer Descriptor: CHLORIDE ION, GLYCEROL, Non-POU domain-containing octamer-binding protein, ... Authors: Knott, G.J, Bond, C.S. Deposit date: 2016-02-26 Release date: 2016-11-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A crystallographic study of human NONO (p54(nrb)): overcoming pathological problems with purification, data collection and noncrystallographic symmetry. Acta Crystallogr D Struct Biol, 72, 2016
8ESQ	Ytm1 associated nascent 60S ribosome State 2 Descriptor: 25S rRNA (cytosine-C(5))-methyltransferase nop2, 60S ribosomal protein L13, 60S ribosomal protein L14, ... Authors: Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. Deposit date: 2022-10-14 Release date: 2022-11-30 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
8EUY	Ytm1 associated nascent 60S ribosome (-fkbp39) State 1A Descriptor: 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... Authors: Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. Deposit date: 2022-10-19 Release date: 2022-11-30 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3 Å) Cite: Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
5K1H	eIF3b relocated to the intersubunit face to interact with eIF1 and below the eIF2 ternary-complex. from the structure of a partial yeast 48S preinitiation complex in closed conformation. Descriptor: Eukaryotic translation initiation factor 3 subunit B, eIF3a C-terminal tail Authors: Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. Deposit date: 2016-05-18 Release date: 2016-07-13 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (4.9 Å) Cite: eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
5VSU	Structure of yeast U6 snRNP with 2'-phosphate terminated U6 RNA Descriptor: Saccharomyces cerevisiae strain T8 chromosome XII sequence, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA-associated Sm-like protein LSm2, ... Authors: Montemayor, E.J. Deposit date: 2017-05-12 Release date: 2018-05-09 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun, 9, 2018
3LQV	Branch Recognition by SF3b14 Descriptor: ADENINE, Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1 Authors: Schellenberg, M.J, MacMillan, A.M. Deposit date: 2010-02-10 Release date: 2011-01-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Branch Recognition by SF3b14 Rna, 17, 2011
6OWJ	Zn-mediated polymerization of human SFPQ Descriptor: Splicing factor, proline- and glutamine-rich, ZINC ION Authors: Lee, M. Deposit date: 2019-05-10 Release date: 2020-02-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ. Nucleic Acids Res., 48, 2020
5CA5	Structure of the C. elegans NONO-1 homodimer Descriptor: 1,2-ETHANEDIOL, NONO-1 Authors: Knott, G.J, Bond, C.S. Deposit date: 2015-06-29 Release date: 2015-12-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Caenorhabditis elegans NONO-1: Insights into DBHS protein structure, architecture, and function. Protein Sci., 24, 2015
6PAI	Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and sulfonamide E7820 Descriptor: 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DDB1- and CUL4-associated factor 15, ... Authors: Volkov, O.A, Du, X. Deposit date: 2019-06-11 Release date: 2019-09-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural Basis and Kinetic Pathway of RBM39 Recruitment to DCAF15 by a Sulfonamide Molecular Glue E7820. Structure, 27, 2019
6Q0W	Structure of DDB1-DDA1-DCAF15 complex bound to Indisulam and RBM39 Descriptor: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ... Authors: Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. Deposit date: 2019-08-02 Release date: 2019-11-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
6Q0R	Structure of DDB1-DDA1-DCAF15 complex bound to E7820 and RBM39 Descriptor: 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ... Authors: Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. Deposit date: 2019-08-02 Release date: 2019-11-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
6Q0V	Structure of DDB1-DDA1-DCAF15 complex bound to tasisulam and RBM39 Descriptor: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ... Authors: Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. Deposit date: 2019-08-02 Release date: 2019-11-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
5FJ4	Structure of the standard kink turn HmKt-7 as stem loop bound with U1A and L7Ae proteins Descriptor: 50S RIBOSOMAL PROTEIN L7AE, HMKT-7, U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A Authors: Huang, L, Lilley, D.M.J. Deposit date: 2015-10-06 Release date: 2016-05-25 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.95 Å) Cite: A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function. Nucleic Acids Res., 44, 2016
6R5K	Cryo-EM structure of a poly(A) RNP bound to the Pan2-Pan3 deadenylase Descriptor: MAGNESIUM ION, PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAN2-PAN3 deadenylation complex subunit PAN3, ... Authors: Schaefer, I.B, Conti, E. Deposit date: 2019-03-25 Release date: 2019-05-29 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase. Cell, 177, 2019
7ZHR	Complex structure of drosophila Unr CSD789 and pAbp RRM3 Descriptor: Polyadenylate-binding protein, Upstream of N-ras, isoform A Authors: Hollmann, N.M, Jagtap, P.K.A, Hennig, J. Deposit date: 2022-04-07 Release date: 2022-12-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.99 Å) Cite: Upstream of N-Ras C-terminal cold shock domains mediate poly(A) specificity in a novel RNA recognition mode and bind poly(A) binding protein. Nucleic Acids Res., 51, 2023
7ZNJ	Structure of an ALYREF-exon junction complex hexamer Descriptor: Eukaryotic initiation factor 4A-III, N-terminally processed, MAGNESIUM ION, ... Authors: Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C. Deposit date: 2022-04-21 Release date: 2023-04-12 Last modified: 2023-05-24 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: mRNA recognition and packaging by the human transcription-export complex. Nature, 616, 2023
7ZNK	Structure of an endogenous human TREX complex bound to mRNA Descriptor: RNA, Spliceosome RNA helicase DDX39B, THO complex subunit 1, ... Authors: Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C. Deposit date: 2022-04-21 Release date: 2023-05-03 Last modified: 2023-05-24 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: mRNA recognition and packaging by the human transcription-export complex. Nature, 616, 2023
7ZJ2	Amyloid fibril (in vitro) from full-length hnRNPA1 protein Descriptor: Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 Authors: Sharma, K, Banerjee, S, Schmidt, M, Faendrich, M. Deposit date: 2022-04-08 Release date: 2023-08-02 Last modified: 2023-08-09 Method: ELECTRON MICROSCOPY (3.32 Å) Cite: Cryo-EM Structure of the Full-length hnRNPA1 Amyloid Fibril. J.Mol.Biol., 435, 2023
8A98	CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT Descriptor: 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... Authors: Rajan, K.S, Yonath, A, Bashan, A. Deposit date: 2022-06-28 Release date: 2023-10-11 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.46 Å) Cite: Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
8A3W	CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE Descriptor: 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, 40S ribosomal protein S2, ... Authors: Rajan, K.S, Yonath, A, Bashan, A. Deposit date: 2022-06-09 Release date: 2023-12-20 Method: ELECTRON MICROSCOPY (2.89 Å) Cite: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE To Be Published
7SP0	Crystal structure of human SFPQ L534I mutant in complex with zinc Descriptor: Splicing factor, proline- and glutamine-rich, ZINC ION Authors: Lee, M. Deposit date: 2021-11-01 Release date: 2022-10-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons. Open Biology, 12, 2022

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