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5K1H

eIF3b relocated to the intersubunit face to interact with eIF1 and below the eIF2 ternary-complex. from the structure of a partial yeast 48S preinitiation complex in closed conformation.

Summary for 5K1H
Entry DOI10.2210/pdb5k1h/pdb
EMDB information8195
DescriptorEukaryotic translation initiation factor 3 subunit B, eIF3a C-terminal tail (2 entities in total)
Functional Keywordseukaryotic translation initiation, ribosome, eif3 peripheral subunits, cryo-em, translation
Biological sourceHomo sapiens (Human)
More
Cellular locationCytoplasm : P55884
Total number of polymer chains2
Total formula weight71588.79
Authors
Simonetti, A.,Brito Querido, J.,Myasnikov, A.G.,Mancera-Martinez, E.,Renaud, A.,Kuhn, L.,Hashem, Y. (deposition date: 2016-05-18, release date: 2016-07-13, Last modification date: 2018-01-31)
Primary citationSimonetti, A.,Brito Querido, J.,Myasnikov, A.G.,Mancera-Martinez, E.,Renaud, A.,Kuhn, L.,Hashem, Y.
eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition.
Mol.Cell, 63:206-217, 2016
Cited by
PubMed: 27373335
DOI: 10.1016/j.molcel.2016.05.033
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.9 Å)
Structure validation

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