5K1H
eIF3b relocated to the intersubunit face to interact with eIF1 and below the eIF2 ternary-complex. from the structure of a partial yeast 48S preinitiation complex in closed conformation.
Summary for 5K1H
Entry DOI | 10.2210/pdb5k1h/pdb |
EMDB information | 8195 |
Descriptor | Eukaryotic translation initiation factor 3 subunit B, eIF3a C-terminal tail (2 entities in total) |
Functional Keywords | eukaryotic translation initiation, ribosome, eif3 peripheral subunits, cryo-em, translation |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : P55884 |
Total number of polymer chains | 2 |
Total formula weight | 71588.79 |
Authors | Simonetti, A.,Brito Querido, J.,Myasnikov, A.G.,Mancera-Martinez, E.,Renaud, A.,Kuhn, L.,Hashem, Y. (deposition date: 2016-05-18, release date: 2016-07-13, Last modification date: 2018-01-31) |
Primary citation | Simonetti, A.,Brito Querido, J.,Myasnikov, A.G.,Mancera-Martinez, E.,Renaud, A.,Kuhn, L.,Hashem, Y. eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63:206-217, 2016 Cited by PubMed: 27373335DOI: 10.1016/j.molcel.2016.05.033 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.9 Å) |
Structure validation
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