PDB: 14265 resultsInfo pagesStatus searchChemie searchBIRD

---

1L9U	THERMUS AQUATICUS RNA POLYMERASE HOLOENZYME AT 4 A RESOLUTION Descriptor: MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ... Authors: Murakami, K.S, Masuda, S, Darst, S.A. Deposit date: 2002-03-26 Release date: 2002-05-22 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (4 Å) Cite: Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution. Science, 296, 2002
1L9Z	Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution Descriptor: MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ... Authors: Murakami, K.S, Masuda, S, Campbell, E.A, Muzzin, O, Darst, S.A. Deposit date: 2002-03-27 Release date: 2002-05-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (6.5 Å) Cite: Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex. Science, 296, 2002
3SFG	crystal structure of murine norovirus RNA dependent RNA polymerase in complex with 2thiouridine(2TU) Descriptor: 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, GLYCEROL, MAGNESIUM ION, ... Authors: Kim, K.H, Alam, I. Deposit date: 2011-06-13 Release date: 2012-05-09 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.209 Å) Cite: Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin. Virology, 426, 2012
1YVX	Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor Descriptor: 3-[ISOPROPYL(4-METHYLBENZOYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION Authors: Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. Deposit date: 2005-02-16 Release date: 2005-03-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J.Biol.Chem., 280, 2005
2PPB	Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the ntp substrate analog and antibiotic streptolydigin Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3'), ... Authors: Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I, Landick, R. Deposit date: 2007-04-28 Release date: 2007-07-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis for substrate loading in bacterial RNA polymerase. Nature, 448, 2007
1YVZ	Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor Descriptor: 3-[(2,4-DICHLOROBENZOYL)(ISOPROPYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION Authors: Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. Deposit date: 2005-02-16 Release date: 2005-03-22 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J.Biol.Chem., 280, 2005
2GHO	Recombinant Thermus aquaticus RNA polymerase for Structural Studies Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta',DNA-directed RNA polymerase subunit beta' Authors: Lamour, V, Darst, S.A. Deposit date: 2006-03-27 Release date: 2006-05-23 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (5 Å) Cite: Recombinant Thermus aquaticus RNA Polymerase for Structural Studies. J.Mol.Biol., 359, 2006
1YNN	Taq RNA polymerase-rifampicin complex Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... Authors: Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A. Deposit date: 2005-01-24 Release date: 2005-03-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase Embo J., 24, 2005
7VB4	A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically dynamic RNA-dependent RNA polymerase Descriptor: GLYCEROL, MAGNESIUM ION, RNA-directed RNA polymerase nsP4 Authors: Tan, Y.B, Luo, D. Deposit date: 2021-08-30 Release date: 2022-02-16 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold. Nucleic Acids Res., 50, 2022
7VW5	Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold Descriptor: MAGNESIUM ION, RNA-directed RNA polymerase nsP4 Authors: Tan, Y.B, Luo, D. Deposit date: 2021-11-09 Release date: 2022-02-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold. Nucleic Acids Res., 50, 2022
2PI5	T7 RNA polymerase complexed with a phi10 promoter Descriptor: 5'-D(*CP*TP*TP*C*CP*TP*AP*TP*AP*GP*TP*GP*AP*GP*TP*CP*GP*TP*AP*TP*TP*A)-3', 5'-D(*TP*AP*AP*TP*AP*CP*GP*AP*CP*TP*CP*AP*CP*T)-3', DNA-directed RNA polymerase Authors: Kennedy, W.P, Momand, J.R, Yin, Y.W. Deposit date: 2007-04-12 Release date: 2007-06-19 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Mechanism for de novo RNA synthesis and initiating nucleotide specificity by t7 RNA polymerase. J.Mol.Biol., 370, 2007
1I6V	THERMUS AQUATICUS CORE RNA POLYMERASE-RIFAMPICIN COMPLEX Descriptor: DNA-DIRECTED RNA POLYMERASE, MAGNESIUM ION, RIFAMPICIN, ... Authors: Campbell, E.A, Korzheva, N, Mustaev, A, Murakami, K, Goldfarb, A, Darst, S.A. Deposit date: 2001-03-05 Release date: 2001-04-18 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural mechanism for rifampicin inhibition of bacterial rna polymerase. Cell(Cambridge,Mass.), 104, 2001
1QKL	hRPABC14.4, essential subunit of human RNA polymerases I, II and III Descriptor: DNA-DIRECTED RNA POLYMERASE II 14.4 KD POLYPEPTIDE Authors: Del Rio-Portilla, F, Gaskell, A.G, Gilbert, D, Ladias, J.A.A, Wagner, G. Deposit date: 1999-07-26 Release date: 1999-11-07 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution Structure of the Hrpabc14.4 Subunit of Human RNA Polymerases Nat.Struct.Biol., 6, 1999
7ASV	Crystal structure of tWHD2 of Rpc5 subunit of human RNA Polymerase III Descriptor: ACETATE ION, DNA-directed RNA polymerase III subunit RPC5 Authors: Vannini, A, Abascal-Palacios, G, Ramsay, E.P. Deposit date: 2020-10-28 Release date: 2020-12-30 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structure of human RNA polymerase III. Nat Commun, 11, 2020
7ASU	Crystal structure of tWHD1 of Rpc5 subunit of human RNA Polymerase III Descriptor: DNA-directed RNA polymerase III subunit RPC5, ZINC ION Authors: Vannini, A, Abascal-Palacios, G, Ramsay, E.P. Deposit date: 2020-10-28 Release date: 2020-12-30 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Structure of human RNA polymerase III. Nat Commun, 11, 2020
4B02	The C-terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage phi6 RNA-Dependent RNA Polymerase Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE Authors: Sarin, L.P, Wright, S, Chen, Q, Degerth, L.H, Stuart, D.I, Grimes, J.M, Bamford, D.H, Poranen, M.M. Deposit date: 2012-06-27 Release date: 2012-08-01 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: The C-Terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage Phi6 RNA-Dependent RNA Polymerase. Virology, 432, 2012
2PUS	Unprecedented activation mechanism of a non-canonical RNA-dependent RNA polymerase Descriptor: IBDV VP1 RNA-dependant RNA polymerase Authors: Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N. Deposit date: 2007-05-09 Release date: 2007-11-27 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Activation mechanism of a noncanonical RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.Usa, 104, 2007
1HQM	CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Minakhin, L, Bhagat, S, Brunning, A, Campbell, E.A, Darst, S.A, Ebright, R.H, Severinov, K. Deposit date: 2000-12-18 Release date: 2001-02-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly. Proc.Natl.Acad.Sci.USA, 98, 2001
1MSW	Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase Descriptor: DNA-directed RNA polymerase, Non-Template DNA, RNA message, ... Authors: Yin, Y.W, Steitz, T.A. Deposit date: 2002-09-19 Release date: 2002-11-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase Science, 298, 2002
1H38	Structure of a T7 RNA polymerase elongation complex at 2.9A resolution Descriptor: 5'-D(*GP*GP*GP*AP*AP*TP*CP*GP*AP*CP *AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*CP)-3', 5'-R(*AP*AP*CP*UP*GP*CP*GP*GP*CP*GP *AP*U)-3', ... Authors: Tahirov, T.H, Temyakov, D, Anikin, M, Patlan, V, McAllister, W.T, Vassylyev, D.G, Yokoyama, S. Deposit date: 2002-08-24 Release date: 2002-11-20 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of a T7 RNA Polymerase Elongation Complex at 2.9 A Resolution Nature, 420, 2002
5I62	Crystal structure of the insertion loop deletion mutant of the RNA-dependent RNA polymerase of a human picorbirnavirus Descriptor: Potential RNA-dependent RNA polymerase Authors: Collier, A.M, Guo, Y.R, Tao, Y.J. Deposit date: 2016-02-15 Release date: 2016-03-16 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.001 Å) Cite: Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus. Plos Pathog., 12, 2016
5HFZ	Mmi1 YTH domain Descriptor: YTH domain-containing protein mmi1 Authors: Chatterjee, D, Goldgur, Y, Shuman, S. Deposit date: 2016-01-07 Release date: 2016-02-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast. Rna, 22, 2016
5I61	Crystal structure of the RNA-dependent RNA polymerase of a human picorbirnavirus Descriptor: Potential RNA-dependent RNA polymerase Authors: Collier, A.M, Guo, Y.R, Tao, Y.J. Deposit date: 2016-02-15 Release date: 2016-03-16 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus. Plos Pathog., 12, 2016
2PA8	X-Ray Crystal Structure of the D/L Subcomplex of the Sulfolobus Solfataricus RNA polymerase Descriptor: DNA-directed RNA polymerase subunit D, DNA-directed RNA polymerase subunit L, FE3-S4 CLUSTER, ... Authors: Hirata, A, Murakami, K.S. Deposit date: 2007-03-27 Release date: 2008-02-05 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.76 Å) Cite: The X-ray crystal structure of RNA polymerase from Archaea. Nature, 451, 2008
7BTF	SARS-CoV-2 RNA-dependent RNA polymerase in complex with cofactors in reduced condition Descriptor: Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ... Authors: Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. Deposit date: 2020-04-01 Release date: 2020-04-08 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (2.95 Å) Cite: Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science, 368, 2020

<16171819202122232425262728293031>