PDB: 8717 resultsInfo pagesStatus searchChemie searchBIRD

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7RPW	Archaeal DNA ligase and heterotrimeric PCNA in complex with adenylated DNA Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ... Authors: Sverzhinsky, A, Pascal, J.M. Deposit date: 2021-08-04 Release date: 2021-11-17 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.38 Å) Cite: Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure, 30, 2022
7RPO	Archaeal DNA ligase and heterotrimeric PCNA in complex with non-ligatable DNA Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ... Authors: Sverzhinsky, A, Pascal, J.M. Deposit date: 2021-08-03 Release date: 2021-11-17 Last modified: 2022-03-16 Method: ELECTRON MICROSCOPY (4.16 Å) Cite: Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure, 30, 2022
7RPX	Archaeal DNA ligase and heterotrimeric PCNA in complex with end-joined DNA Descriptor: DNA ligase, DNA polymerase sliding clamp 1, DNA polymerase sliding clamp 2, ... Authors: Sverzhinsky, A, Pascal, J.M. Deposit date: 2021-08-04 Release date: 2021-11-17 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure, 30, 2022
5UOJ	THE STRUCTURE OF THE MAP KINASE P38 AT 2.1 ANGSTROMS RESOLUTION Descriptor: Mitogen-activated protein kinase 14 Authors: CHLEBOWICZ, J, WANG, Z, GOLDSMITH, E.J. Deposit date: 2017-01-31 Release date: 2017-02-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The structure of mitogen-activated protein kinase p38 at 2.1-A resolution. Proc. Natl. Acad. Sci. U.S.A., 94, 1997
8GI5	Cryo-EM of self-assembling pyrene peptide with Ca2+ Descriptor: Pyrene peptide Authors: Rich-New, S.T, Guo, J, Xu, B, Wang, F. Deposit date: 2023-03-13 Release date: 2023-06-14 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (3 Å) Cite: Hierarchical Assembly of Intrinsically Disordered Short Peptides. Chem, 9, 2023
5VHR	Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle Descriptor: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... Authors: Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. Deposit date: 2017-04-13 Release date: 2017-08-23 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (7.7 Å) Cite: Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle. Mol. Cell, 67, 2017
8B8T	Open conformation of the complex of DNA ligase I on PCNA and DNA in the presence of ATP Descriptor: DNA ligase 1, Proliferating cell nuclear antigen Authors: Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A. Deposit date: 2022-10-05 Release date: 2023-01-11 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing. Nat Commun, 13, 2022
5VHN	Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle Descriptor: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... Authors: Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. Deposit date: 2017-04-13 Release date: 2017-08-23 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (7.3 Å) Cite: Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle. Mol. Cell, 67, 2017
8UI9	Cryo-EM map of human clamp-clamp loader ATAD5-RFC-cracked PCNA complex in intermediate state 2 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase family AAA domain-containing protein 5, MAGNESIUM ION, ... Authors: Wang, F, He, Q, Li, H. Deposit date: 2023-10-10 Release date: 2024-05-29 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader. Nat.Struct.Mol.Biol., 2024
5VHJ	Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle Descriptor: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... Authors: Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. Deposit date: 2017-04-13 Release date: 2017-08-23 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (8.5 Å) Cite: Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle. Mol. Cell, 67, 2017
5VHQ	Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle Descriptor: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... Authors: Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. Deposit date: 2017-04-13 Release date: 2017-08-23 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (8.9 Å) Cite: Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle. Mol. Cell, 67, 2017
5I1Q	Second bromodomain of TAF1 bound to a pyrrolopyridone compound Descriptor: 3-[6-(but-3-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl]-N,N-dimethylbenzamide, Transcription initiation factor TFIID subunit 1 Authors: Tang, Y, Poy, F, Bellon, S.F. Deposit date: 2016-01-09 Release date: 2016-06-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains. J.Med.Chem., 59, 2016
8UI8	Cryo-EM map of human clamp-clamp loader ATAD5-RFC-two PCNAs complex in intermediate state 3 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase family AAA domain-containing protein 5, MAGNESIUM ION, ... Authors: Wang, F, He, Q, Li, H. Deposit date: 2023-10-10 Release date: 2024-05-29 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader. Nat.Struct.Mol.Biol., 2024
7AG0	Complex between the bone morphogenetic protein 2 and its antagonist Noggin Descriptor: Bone morphogenetic protein 2, GLYCEROL, Noggin Authors: Robert, C, Bruck, F, Herman, R, Vandevenne, M, Filee, P, Kerff, F, Matagne, A. Deposit date: 2020-09-21 Release date: 2022-04-13 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.104 Å) Cite: Structural analysis of the interaction between human cytokine BMP-2 and the antagonist Noggin reveals molecular details of cell chondrogenesis inhibition. J.Biol.Chem., 299, 2023
7AYY	Structure of the human 8-oxoguanine DNA Glycosylase hOGG1 in complex with activator TH10785 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, N-glycosylase/DNA lyase, ... Authors: Masuyer, G, Davies, J.R, Stenmark, P. Deposit date: 2020-11-13 Release date: 2022-06-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2 Å) Cite: Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science, 376, 2022
2OKR	Crystal Structure of the P38a-MAPKAP kinase 2 Heterodimer Descriptor: MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14 Authors: Ter Haar, E. Deposit date: 2007-01-17 Release date: 2007-02-06 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of the P38alpha-MAPKAP kinase 2 heterodimer. J.Biol.Chem., 282, 2007
5VHP	Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle Descriptor: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... Authors: Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. Deposit date: 2017-04-13 Release date: 2017-08-23 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (7.9 Å) Cite: Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle. Mol. Cell, 67, 2017
8OK1	WD repeat containing protein 5 (WDR5)- N225A mutant Descriptor: Glutathione S-transferase class-mu 26 kDa isozyme,WD repeat-containing protein 5 Authors: Wolf, E, Boergel, A. Deposit date: 2023-03-26 Release date: 2024-04-03 Method: X-RAY DIFFRACTION (1.38 Å) Cite: A structural competition involving WDR5 times circadian oscillations To Be Published
7UUQ	Cryo-EM of self-assembling pyrene IDP Descriptor: Pyrene-containing peptide fibril Authors: Wang, F, Guo, J, Xu, B, Egelman, E.H. Deposit date: 2022-04-28 Release date: 2023-05-10 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Hierarchical Assembly of Intrinsically Disordered Short Peptides. Chem, 9, 2023
8K8T	Structure of CUL3-RBX1-KLHL22 complex Descriptor: Cullin-3, Kelch-like protein 22 Authors: Wang, W, Ling, L, Dai, Z, Zuo, P, Yin, Y. Deposit date: 2023-07-31 Release date: 2024-05-22 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3 KLHL22. Nat Commun, 15, 2024
8I02	Cryo-EM structure of the SIN3S complex from S. pombe Descriptor: Chromatin modification-related protein eaf3, Cph1, Histone deacetylase clr6, ... Authors: Wang, C, Guo, Z, Zhan, X. Deposit date: 2023-01-10 Release date: 2023-05-03 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Two assembly modes for SIN3 histone deacetylase complexes. Cell Discov, 9, 2023
8I03	Cryo-EM structure of the SIN3L complex from S. pombe Descriptor: Chromatin modification-related protein png2, Histone deacetylase clr6, POTASSIUM ION, ... Authors: Wang, C, Guo, Z, Zhan, X. Deposit date: 2023-01-10 Release date: 2023-05-03 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Two assembly modes for SIN3 histone deacetylase complexes. Cell Discov, 9, 2023
7BED	X-ray structure of WDR5 bound to the WDR5 win motif peptide Descriptor: SULFATE ION, WD repeat-containing protein 5 Authors: McVey, C.E, Kaye, K.M. Deposit date: 2020-12-23 Release date: 2021-12-08 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.26 Å) Cite: MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res., 49, 2021
3UV5	Crystal Structure of the tandem bromodomains of human Transcription initiation factor TFIID subunit 1 (TAF1) Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Transcription initiation factor TFIID subunit 1 Authors: Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2011-11-29 Release date: 2012-01-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
7BCY	X-ray structure of WDR5delta24 bound to the Kaposi's sarcoma herpesvirus LANA win motif peptide Descriptor: ORF 73, WD repeat-containing protein 5 Authors: McVey, C.E, Kaye, K.M. Deposit date: 2020-12-21 Release date: 2021-12-08 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res., 49, 2021

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