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5U2M
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BU of 5u2m by Molmil
Crystal structure of human NAMPT with A-1293201
Descriptor: N-[4-({[(3S)-oxolan-3-yl]methyl}carbamoyl)phenyl]-1,3-dihydro-2H-isoindole-2-carboxamide, Nicotinamide phosphoribosyltransferase, SULFATE ION
Authors:Longenecker, K.L, Raich, D, Korepanova, A.V.
Deposit date:2016-11-30
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors.
Mol. Cancer Ther., 16, 2017
4LTS
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BU of 4lts by Molmil
Discovery of Potent and Efficacious Cyanoguanidine-containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Descriptor: 1,2-ETHANEDIOL, 2-cyano-1-pyridin-4-yl-3-(4-{[3-(trifluoromethoxy)phenyl]sulfonyl}benzyl)guanidine, Nicotinamide phosphoribosyltransferase, ...
Authors:Zheng, X, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Han, B, Ho, Y, Kley, N, Lin, J, Reynoids, D.J, Sharma, G, Smith, C.C, Wang, Z, Dragovich, P.S, Oh, A, Wang, W, Zak, M, Wang, L, Yuen, P, Bair, K.W.
Deposit date:2013-07-23
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.692 Å)
Cite:Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors.
Bioorg.Med.Chem.Lett., 24, 2014
4KFN
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BU of 4kfn by Molmil
Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Descriptor: 1,2-ETHANEDIOL, N-[4-(piperidin-1-ylsulfonyl)benzyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide, Nicotinamide phosphoribosyltransferase, ...
Authors:Zheng, X, Bauer, P, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Han, B, Ho, Y, Kley, N, Lin, J, Reynolds, D.J, Sharma, G, Smith, C.C, Wang, Z, Dragovich, P.S, Gunzner-Toste, J, Liederer, B.M, Ly, J, O'Brien, T, Oh, A, Wang, L, Wang, W, Xiao, Y, Zak, M, Zhao, G, Yuen, P, Bair, K.W.
Deposit date:2013-04-27
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (nampt) inhibitors.
J.Med.Chem., 56, 2013
6XJ6
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BU of 6xj6 by Molmil
Crystal structure of the helical cell shape determining protein Pgp2 from Campylobacter jejuni
Descriptor: Pgp2
Authors:Lin, C.S, Chan, A.C, Murphy, M.E.
Deposit date:2020-06-23
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni.
J.Biol.Chem., 296, 2021
1PPR
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BU of 1ppr by Molmil
PERIDININ-CHLOROPHYLL-PROTEIN OF AMPHIDINIUM CARTERAE
Descriptor: CHLOROPHYLL A, DIGALACTOSYL DIACYL GLYCEROL (DGDG), PERIDININ, ...
Authors:Hofmann, E, Welte, W, Diederichs, K.
Deposit date:1996-03-06
Release date:1997-08-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of light harvesting by carotenoids: peridinin-chlorophyll-protein from Amphidinium carterae.
Science, 272, 1996
6XJ7
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BU of 6xj7 by Molmil
Crystal structure of the helical cell shape determining protein Pgp2 (K307A mutant) from Campylobacter jejuni
Descriptor: Pgp2
Authors:Lin, C.S, Chan, A.C, Murphy, M.E.
Deposit date:2020-06-23
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni.
J.Biol.Chem., 296, 2021
9CT1
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BU of 9ct1 by Molmil
Complex between the porcine trypsin and M271 a Kunitz-STI from Solanum tuberosum
Descriptor: CALCIUM ION, KTI-A protein, Trypsin
Authors:Campuzano-Gonzalez, A, Rudino-Pinera, E.
Deposit date:2024-07-24
Release date:2025-05-14
Last modified:2025-05-21
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural determination of a new non-canonical inhibition complex between porcine trypsin and M271 a potato Kunitz-STI inhibitor.
Biochem.Biophys.Res.Commun., 768, 2025
3G8E
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BU of 3g8e by Molmil
Crystal Structure of Rattus norvegicus Visfatin/PBEF/Nampt in Complex with an FK866-based inhibitor
Descriptor: 3-[(1E)-3-oxo-3-({4-[1-(phenylcarbonyl)piperidin-4-yl]butyl}amino)prop-1-en-1-yl]-1-beta-D-ribofuranosylpyridinium, Nicotinamide phosphoribosyltransferase
Authors:Kang, G.B, Bae, M.H, Kim, M.K, Im, I, Kim, Y.C, Eom, S.H.
Deposit date:2009-02-12
Release date:2009-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of Rattus norvegicus Visfatin/PBEF/Nampt in complex with an FK866-based inhibitor
Mol.Cells, 27, 2009
4HEF
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BU of 4hef by Molmil
Structure of avibactam bound to Pseudomonas aeruginosa AmpC
Descriptor: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase, GLYCEROL
Authors:Lahiri, S.D.
Deposit date:2012-10-03
Release date:2013-06-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-Lactamases
Antimicrob.Agents Chemother., 57, 2013
3ZX1
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BU of 3zx1 by Molmil
Multicopper oxidase from Campylobacter jejuni: a metallo-oxidase
Descriptor: 1,2-ETHANEDIOL, COPPER (II) ION, OXIDOREDUCTASE, ...
Authors:Silva, C.S, Durao, P, Fillat, A, Lindley, P.F, Martins, L.O, Bento, I.
Deposit date:2011-08-04
Release date:2011-12-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of the Multicopper Oxidase from the Pathogenic Bacterium Campylobacter Jejuni Cgug11284: Characterization of a Metallo-Oxidase.
Metallomics, 4, 2012
4ATM
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BU of 4atm by Molmil
Crystal structure of the BAR domain of human Amphiphysin, isoform 1 at 1.8 Angstrom resolution featuring increased order at the N- terminus.
Descriptor: 1,2-ETHANEDIOL, AMPHIPHYSIN, GLYCEROL
Authors:Allerston, C.K, Krojer, T, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, von Delft, F, Gileadi, O.
Deposit date:2012-05-08
Release date:2012-05-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.783 Å)
Cite:Crystal Structure of the Bar Domain of Human Amphiphysin, Isoform 1
To be Published
2WY4
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BU of 2wy4 by Molmil
Structure of bacterial globin from Campylobacter jejuni at 1.35 A resolution
Descriptor: CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SINGLE DOMAIN HAEMOGLOBIN
Authors:Barynin, V.V, Sedelnikova, S.E, Shepherd, M, Wu, G, Poole, R.K, Rice, D.W.
Deposit date:2009-11-11
Release date:2010-02-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Single-Domain Globin from the Pathogenic Bacterium Campylobacter Jejuni: Novel D-Helix Conformation, Proximal Hydrogen Bonding that Influences Ligand Binding, and Peroxidase-Like Redox Properties.
J.Biol.Chem., 285, 2010
4BJ4
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BU of 4bj4 by Molmil
Structure of Pseudomonas aeruginosa amidase Ampdh2
Descriptor: AMPDH2, CITRATE ANION
Authors:Martinez-Caballero, C.S, Carrasco-Lopez, C, Artola-Recolons, C, Hermoso, J.A.
Deposit date:2013-04-16
Release date:2013-07-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.722 Å)
Cite:Reaction Products and the X-Ray Structure of Ampdh2, a Virulence Determinant of Pseudomonas Aeruginosa.
J.Am.Chem.Soc., 135, 2013
5UPF
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BU of 5upf by Molmil
Crystal structure of human NAMPT with isoindoline urea inhibitor compound 53
Descriptor: 5-fluoro-N-{4-[1-(2-hydroxy-2-methylpropanoyl)piperidin-4-yl]phenyl}-2H-isoindole-2-carboxamide, Nicotinamide phosphoribosyltransferase
Authors:Longenecker, K.L, Raich, D, Korepanova, A.V.
Deposit date:2017-02-02
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg. Med. Chem. Lett., 27, 2017
2V25
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BU of 2v25 by Molmil
Structure of the Campylobacter jejuni antigen Peb1A, an aspartate and glutamate receptor with bound aspartate
Descriptor: ASPARTIC ACID, MAJOR CELL-BINDING FACTOR, ZINC ION
Authors:Muller, A, Dodson, E, del Rocio Leon-Kempis, M, Kelly, D.J, Wilkinson, A.J, Wilson, K.S.
Deposit date:2007-06-01
Release date:2007-06-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:A Bacterial Virulence Factor with a Dual Role as an Adhesin and a Solute Binding-Protein: The Crystal Structure at 1.5 A Resolution of the Peb1A Protein from the Food-Borne Human Pathogen Campylobacter Jejuni
J.Mol.Biol., 372, 2007
5UPE
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BU of 5upe by Molmil
Crystal structure of human NAMPT with isoindoline urea inhibitor compound 5
Descriptor: N-{4-[(3-phenylpropyl)carbamoyl]phenyl}-2H-isoindole-2-carboxamide, Nicotinamide phosphoribosyltransferase
Authors:Longenecker, K.L, Raich, D, Korepanova, A.V.
Deposit date:2017-02-02
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg. Med. Chem. Lett., 27, 2017
4BXJ
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BU of 4bxj by Molmil
CRYSTAL STRUCTURE OF AMPDH3 FROM PSEUDOMONAS AERUGINOSA
Descriptor: AMPDH3, GLYCEROL
Authors:Carrasco-Lopez, C, Hermoso, J.A.
Deposit date:2013-07-12
Release date:2013-10-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Cell-Wall Remodeling by the Zinc-Protease Ampdh3 from Pseudomonas Aeruginosa.
J.Am.Chem.Soc., 135, 2013
3KUO
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BU of 3kuo by Molmil
X-ray structure of the metcyano form of dehaloperoxidase from amphitrite ornata: evidence for photoreductive lysis of iron-cyanide bond
Descriptor: CYANIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Serrano, V.S, Chen, Z, Gaff, J.F, Rose, R, Franzen, S.
Deposit date:2009-11-27
Release date:2010-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:X-ray structure of the metcyano form of dehaloperoxidase from Amphitrite ornata: evidence for photoreductive dissociation of the iron-cyanide bond.
Acta Crystallogr.,Sect.D, 66, 2010
3ORD
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BU of 3ord by Molmil
Structural Evidence for Stabilization of Inhibitor Binding by a Protein Cavity in the Dehaloperoxidase-Hemoglobin from Amphitrite ornata
Descriptor: Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:de Serrano, V.S, Franzen, S.
Deposit date:2010-09-06
Release date:2011-09-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural evidence for stabilization of inhibitor binding by a protein cavity in the dehaloperoxidase-hemoglobin from Amphitrite ornata.
Biopolymers, 98, 2012
3HBN
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BU of 3hbn by Molmil
Crystal structure PseG-UDP complex from Campylobacter jejuni
Descriptor: CHLORIDE ION, GLYCEROL, UDP-sugar hydrolase, ...
Authors:Rangarajan, E.S, Proteau, A, Cygler, M, Matte, A, Sulea, T, Schoenhofen, I.C.
Deposit date:2009-05-04
Release date:2009-05-26
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway.
J.Biol.Chem., 284, 2009
4MO2
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BU of 4mo2 by Molmil
Crystal Structure of UDP-N-acetylgalactopyranose mutase from Campylobacter jejuni
Descriptor: AMMONIUM ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Dalrymple, S.A, Protsko, C, Poulin, M.B, Lowary, T.L, Sanders, D.A.R.
Deposit date:2013-09-11
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specificity of a UDP-GalNAc Pyranose-Furanose Mutase: A Potential Therapeutic Target for Campylobacter jejuni Infections.
Chembiochem, 15, 2014
9CSZ
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BU of 9csz by Molmil
Crystallographic structure of M271 a new Kunitz-STI from potato
Descriptor: 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, KTI-A protein, ...
Authors:Campuzano-Gonzalez, A, Rudino-Pinera, E.
Deposit date:2024-07-24
Release date:2025-05-14
Last modified:2025-05-21
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural determination of a new non-canonical inhibition complex between porcine trypsin and M271 a potato Kunitz-STI inhibitor.
Biochem.Biophys.Res.Commun., 768, 2025
4ETS
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BU of 4ets by Molmil
Crystal structure of Campylobacter jejuni ferric uptake regulator
Descriptor: CHLORIDE ION, Ferric uptake regulation protein, ZINC ION
Authors:Sarvan, S, Brunzelle, J.B, Couture, J.-F.
Deposit date:2012-04-24
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and regulon of Campylobacter jejuni ferric uptake regulator Fur define apo-Fur regulation.
Proc.Natl.Acad.Sci.USA, 109, 2012
5LQ3
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BU of 5lq3 by Molmil
Structures and transport dynamics of the Campylobacter jejuni multidrug efflux pump CmeB
Descriptor: CmeB
Authors:Su, C.C.
Deposit date:2016-08-15
Release date:2017-08-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump.
Nat Commun, 8, 2017
5LDV
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BU of 5ldv by Molmil
Crystal Structures of MOMP from Campylobacter jejuni
Descriptor: CALCIUM ION, MOMP porin, N-OCTANE, ...
Authors:Wallat, G.D, Ferrara, L.M.G, Moynie, L, Naismith, J.H.
Deposit date:2016-06-28
Release date:2016-10-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:MOMP from Campylobacter jejuni Is a Trimer of 18-Stranded beta-Barrel Monomers with a Ca(2+) Ion Bound at the Constriction Zone.
J.Mol.Biol., 428, 2016

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数据于2025-12-03公开中

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