8GFE
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with Z3261 inhibitor
Summary for 8GFE
Entry DOI | 10.2210/pdb8gfe/pdb |
Descriptor | Lytic transglycosylase domain-containing protein, ~{N}-[(2~{R},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-4,5-bis(oxidanyl)-2-[(4-oxidanylidene-3~{H}-pyrido[1,2-a]pyrimidin-2-yl)methoxy]oxan-3-yl]ethanamide, CITRIC ACID, ... (5 entities in total) |
Functional Keywords | soluble lytic transglycosylase, inhibitor, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Campylobacter jejuni |
Total number of polymer chains | 1 |
Total formula weight | 64451.55 |
Authors | van den Akker, F.,Kumar, V. (deposition date: 2023-03-08, release date: 2023-05-24, Last modification date: 2023-08-16) |
Primary citation | Kumar, V.,Boorman, J.,Greenlee, W.J.,Zeng, X.,Lin, J.,van den Akker, F. Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds. Protein Sci., 32:e4683-e4683, 2023 Cited by PubMed: 37209283DOI: 10.1002/pro.4683 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
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