5CJP
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![BU of 5cjp by Molmil](/molmil-images/mine/5cjp) | The Structural Basis for Cdc42-Induced Dimerization of IQGAPs | Descriptor: | Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_a, ... | Authors: | Worthylake, D.K, Boyapati, V.K, LeCour Jr, L. | Deposit date: | 2015-07-14 | Release date: | 2016-08-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Structural Basis for Cdc42-Induced Dimerization of IQGAPs. Structure, 24, 2016
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6TKY
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![BU of 6tky by Molmil](/molmil-images/mine/6tky) | Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42 | Descriptor: | Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10, GLYCEROL | Authors: | Barford, D, Fan, D, Cronin, N, Yang, J. | Deposit date: | 2019-11-29 | Release date: | 2020-01-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10 Biorxiv, 2022
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6Z0L
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![BU of 6z0l by Molmil](/molmil-images/mine/6z0l) | Het-N2 - De novo designed three-helix heterodimer with Cysteine at the N2 position of the alpha-helix | Descriptor: | CADMIUM ION, Cys-N2 Strand, Positive Strand, ... | Authors: | McEwen, A.G, Poussin-Courmontagne, P, Naudin, E.A, DeGrado, W.F, Torbeev, V. | Deposit date: | 2020-05-09 | Release date: | 2021-03-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Acyl Transfer Catalytic Activity in De Novo Designed Protein with N-Terminus of alpha-Helix As Oxyanion-Binding Site. J.Am.Chem.Soc., 143, 2021
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6Z0M
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![BU of 6z0m by Molmil](/molmil-images/mine/6z0m) | Het-Ncap - De novo designed three-helix heterodimer with Cysteine at the Ncap position of the alpha-helix | Descriptor: | Cys-Ncap strand, Positive Strand, SULFATE ION, ... | Authors: | McEwen, A.G, Poussin-Courmontagne, P, Naudin, E.A, DeGrado, W.F, Torbeev, V. | Deposit date: | 2020-05-09 | Release date: | 2021-03-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Acyl Transfer Catalytic Activity in De Novo Designed Protein with N-Terminus of alpha-Helix As Oxyanion-Binding Site. J.Am.Chem.Soc., 143, 2021
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6TKZ
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![BU of 6tkz by Molmil](/molmil-images/mine/6tkz) | |
8IFB
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![BU of 8ifb by Molmil](/molmil-images/mine/8ifb) | Dibekacin-bound E.coli 70S ribosome in the PURE system | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | Deposit date: | 2023-02-17 | Release date: | 2024-02-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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8GI6
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![BU of 8gi6 by Molmil](/molmil-images/mine/8gi6) | Crystal structure of RhoA mutant L69R complexed with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA | Authors: | Chen, X, Qian, X, Chandravanshi, M, Lowy, D.R, Walters, K.J. | Deposit date: | 2023-03-13 | Release date: | 2024-03-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Ras-like GTPases mutant structures To be published
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8GI3
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![BU of 8gi3 by Molmil](/molmil-images/mine/8gi3) | Crystal structure of RhoA mutant L69P complexed with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA | Authors: | Chen, X, Qian, X, Chandravanshi, M, Lowy, D.R, Walters, K.J. | Deposit date: | 2023-03-13 | Release date: | 2024-03-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Ras-like GTPases mutants structure To be published
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8FG0
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![BU of 8fg0 by Molmil](/molmil-images/mine/8fg0) | |
6ULG
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![BU of 6ulg by Molmil](/molmil-images/mine/6ulg) | Cryo-EM structure of the FLCN-FNIP2-Rag-Ragulator complex | Descriptor: | Folliculin, Folliculin-interacting protein 2, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Shen, K, Rogala, K.B, Yu, Z.H, Sabatini, D.M. | Deposit date: | 2019-10-08 | Release date: | 2019-11-20 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex. Cell, 179, 2019
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1NKN
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![BU of 1nkn by Molmil](/molmil-images/mine/1nkn) | VISUALIZING AN UNSTABLE COILED COIL: THE CRYSTAL STRUCTURE OF AN N-TERMINAL SEGMENT OF THE SCALLOP MYOSIN ROD | Descriptor: | S2N51-GCN4 | Authors: | Li, Y, Brown, J.H, Reshetnikova, L, Blazsek, A, Farkas, L, Nyitray, L, Cohen, C. | Deposit date: | 2003-01-03 | Release date: | 2003-07-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Visualization of an unstable coiled coil from the scallop myosin rod Nature, 424, 2003
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6AJ4
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1I2H
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![BU of 1i2h by Molmil](/molmil-images/mine/1i2h) | CRYSTAL STRUCTURE ANALYSIS OF PSD-ZIP45(HOMER1C/VESL-1L)CONSERVED HOMER 1 DOMAIN | Descriptor: | PSD-ZIP45(HOMER-1C/VESL-1L) | Authors: | Irie, K, Nakatsu, T, Mitsuoka, K, Fujiyoshi, Y, Kato, H. | Deposit date: | 2001-02-09 | Release date: | 2002-05-29 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the Homer 1 Family Conserved Region Reveals the Interaction Between the EVH1 Domain and
Own Proline-rich Motif J.Mol.Biol., 318, 2002
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6AJL
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![BU of 6ajl by Molmil](/molmil-images/mine/6ajl) | DOCK7 mutant I1836Y complexed with Cdc42 | Descriptor: | Cell division control protein 42 homolog, Dedicator of cytokinesis protein 7 | Authors: | Kukimoto-Niino, M, Shirouzu, M. | Deposit date: | 2018-08-28 | Release date: | 2019-03-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. Structure, 27, 2019
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7RY0
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![BU of 7ry0 by Molmil](/molmil-images/mine/7ry0) | human Hsp90_MC domain structure | Descriptor: | DIMETHYL SULFOXIDE, GLYCEROL, Heat shock protein HSP 90-alpha | Authors: | Peng, S, Deng, J, Matts, R. | Deposit date: | 2021-08-24 | Release date: | 2022-12-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of the key residue W320 responsible for Hsp90 conformational change. J.Biomol.Struct.Dyn., 2022
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8A3B
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![BU of 8a3b by Molmil](/molmil-images/mine/8a3b) | |
6B0T
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![BU of 6b0t by Molmil](/molmil-images/mine/6b0t) | |
8A8J
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![BU of 8a8j by Molmil](/molmil-images/mine/8a8j) | Complex of RecF and DNA from Thermus thermophilus. | Descriptor: | DNA replication and repair protein RecF, MAGNESIUM ION, Oligo1, ... | Authors: | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | Deposit date: | 2022-06-23 | Release date: | 2023-04-26 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination. Nat.Struct.Mol.Biol., 30, 2023
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8A93
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![BU of 8a93 by Molmil](/molmil-images/mine/8a93) | Complex of RecF-RecR-DNA from Thermus thermophilus. | Descriptor: | DNA replication and repair protein RecF, MAGNESIUM ION, Oligo1, ... | Authors: | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | Deposit date: | 2022-06-27 | Release date: | 2023-04-26 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination. Nat.Struct.Mol.Biol., 30, 2023
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1SJJ
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4GC6
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![BU of 4gc6 by Molmil](/molmil-images/mine/4gc6) | Crystal structure of Dpo4 in complex with N-MC-dAMP opposite dT | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*C)-3'), DNA (5'-D(*TP*CP*AP*TP*GP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... | Authors: | Eoff, R.L, Ketkar, A, Banerjee, S, Zafar, M.K. | Deposit date: | 2012-07-29 | Release date: | 2012-10-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.895 Å) | Cite: | Differential furanose selection in the active sites of archaeal DNA polymerases probed by fixed-conformation nucleotide analogues. Biochemistry, 51, 2012
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6AVU
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![BU of 6avu by Molmil](/molmil-images/mine/6avu) | Human alpha-V beta-3 Integrin (open conformation) in complex with the therapeutic antibody LM609 | Descriptor: | Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ... | Authors: | Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D. | Deposit date: | 2017-09-04 | Release date: | 2017-11-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (35 Å) | Cite: | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance. Structure, 25, 2017
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8B12
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![BU of 8b12 by Molmil](/molmil-images/mine/8b12) | cryo-EM structure of carboxysomal mini-shell: icosahedral assembly from CsoS4A/1A and CsoS2 co-expression (T = 9) | Descriptor: | Carboxysome assembly protein CsoS2B, Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A | Authors: | Ni, T, Jiang, Q, Liu, L.N, Zhang, P. | Deposit date: | 2022-09-09 | Release date: | 2023-08-23 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (1.86 Å) | Cite: | Intrinsically disordered CsoS2 acts as a general molecular thread for alpha-carboxysome shell assembly. Nat Commun, 14, 2023
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8B0Y
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![BU of 8b0y by Molmil](/molmil-images/mine/8b0y) | cryo-EM structure of carboxysomal mini-shell: icosahedral assembly from CsoS4A/1A co-expression (T = 3) | Descriptor: | Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A | Authors: | Ni, T, Jiang, Q, Liu, L.N, Zhang, P. | Deposit date: | 2022-09-08 | Release date: | 2023-08-23 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Intrinsically disordered CsoS2 acts as a general molecular thread for alpha-carboxysome shell assembly. Nat Commun, 14, 2023
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8B11
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![BU of 8b11 by Molmil](/molmil-images/mine/8b11) | cryo-EM structure of carboxysomal mini-shell: icosahedral assembly from CsoS4A/1A and CsoS2 co-expression (T = 4) | Descriptor: | Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A | Authors: | Ni, T, Jiang, Q, Liu, L.N, Zhang, P. | Deposit date: | 2022-09-08 | Release date: | 2023-08-23 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | Intrinsically disordered CsoS2 acts as a general molecular thread for alpha-carboxysome shell assembly. Nat Commun, 14, 2023
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