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3KWV	Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers Descriptor: CALCIUM ION, Lethal factor, Protective antigen PA-63 Authors: Feld, G.K, Kintzer, A.F, Krantz, B.A. Deposit date: 2009-12-01 Release date: 2010-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.101 Å) Cite: Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers. Nat.Struct.Mol.Biol., 17, 2010
8DCM	Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab Descriptor: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/22 Fab heavy chain, BINTOXB/22 Fab light chain, ... Authors: Goldsmith, J.A, McLellan, J.S. Deposit date: 2022-06-16 Release date: 2023-04-05 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin. J.Bacteriol., 205, 2023
8EKM	Clostridioides difficile binary toxin translocase CDTb double mutant - D623A D734A Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION Authors: Abeyawardhane, D.L, Pozharski, E. Deposit date: 2022-09-21 Release date: 2023-09-27 Method: ELECTRON MICROSCOPY (3.56 Å) Cite: Calcium-mediated Pore Formation of Clostridioides difficile Binary Toxin To Be Published
8EKK	Clostridioides difficile binary toxin translocase CDTb wild-type after calcium depletion from receptor binding domain 1 (RBD1) - Class 2 Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION Authors: Abeyawardhane, D.L, Pozharski, E. Deposit date: 2022-09-21 Release date: 2023-09-27 Method: ELECTRON MICROSCOPY (3.28 Å) Cite: Calcium-mediated Pore Formation of Clostridioides difficile Binary Toxin To Be Published
8EKL	Clostridioides difficile binary toxin translocase CDTb wild-type after calcium depletion from receptor binding domain 1 (RBD1) - Class 1 Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION Authors: Abeyawardhane, D.L, Pozharski, E. Deposit date: 2022-09-21 Release date: 2023-09-27 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Calcium-mediated Pore Formation of Clostridioides difficile Binary Toxin To Be Published
6O2N	CDTb Double Heptamer Short Form Modeled from Cryo-EM Map Reconstructed using C7 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-02-24 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6O2M	CDTb Double Heptamer Long Form Modeled from Cryo-EM Map Reconstructed using C7 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-02-24 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (6.3 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6O2O	CDTb Double Heptamer Short Form Modeled from Cryo-EM Map Reconstructed using C1 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-02-24 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.53 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6OKU	CDTb Double Heptamer Long Form Mask 3 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-04-15 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6OKS	CDTb Double Heptamer Long Form Mask 1 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-04-15 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6OKT	CDTb Double Heptamer Long Form Mask 1 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-04-15 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6OKR	CDTb Pre-Insertion form Modeled from Cryo-EM Map Reconstructed using C7 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-04-15 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
3Q8A	Crystal structure of WT Protective Antigen (pH 5.5) Descriptor: CALCIUM ION, Protective antigen Authors: Rajapaksha, M, Lovell, S, Janowiak, B.E, Andra, K.K, Battaile, K.P, Bann, J.G. Deposit date: 2011-01-06 Release date: 2012-01-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.129 Å) Cite: pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
6UZB	Anthrax toxin protective antigen channels bound to edema factor Descriptor: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen Authors: Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. Deposit date: 2019-11-14 Release date: 2020-03-04 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun, 11, 2020
6UZD	Anthrax toxin protective antigen channels bound to edema factor Descriptor: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen Authors: Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. Deposit date: 2019-11-14 Release date: 2020-03-04 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun, 11, 2020
3Q8B	Crystal structure of WT Protective Antigen (pH 9.0) Descriptor: CALCIUM ION, Protective antigen Authors: Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. Deposit date: 2011-01-06 Release date: 2012-02-15 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2 Å) Cite: pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
6UJI	Low resolution crystal structure (5.5 A) of the anthrax toxin protective antigen heptamer prepore D425A mutant Descriptor: Protective antigen PA-63 Authors: Lovell, S, Mehzabeen, N, Battaile, K.P, Bann, J.G. Deposit date: 2019-10-03 Release date: 2020-10-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (5.5 Å) Cite: Structure of the anthrax protective antigen D425A dominant negative mutant reveals a stalled intermediate state of pore maturation. J.Mol.Biol., 2022
3Q8F	Crystal structure of 2-Fluorohistine labeled Protective Antigen (pH 5.8) Descriptor: CALCIUM ION, Protective antigen, TETRAETHYLENE GLYCOL Authors: Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. Deposit date: 2011-01-06 Release date: 2012-02-15 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
6UWT	Clostridium difficile binary toxin translocase CDTb tetradecamer in symmetric conformation Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION Authors: Xu, X, Pozharski, E, des Georges, A. Deposit date: 2019-11-05 Release date: 2020-01-22 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly. Proc.Natl.Acad.Sci.USA, 117, 2020
6V1S	Structure of the Clostridioides difficile transferase toxin Descriptor: ADP-ribosylating binary toxin enzymatic subunit CdtA, ADP-ribosyltransferase binding component, CALCIUM ION Authors: Sheedlo, M.J, Anderson, D.M, Thomas, A.K, Lacy, D.B. Deposit date: 2019-11-21 Release date: 2020-03-18 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural elucidation of theClostridioides difficiletransferase toxin reveals a single-site binding mode for the enzyme. Proc.Natl.Acad.Sci.USA, 117, 2020
6UWR	Clostridium difficile binary toxin translocase CDTb in asymmetric tetradecamer conformation Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION Authors: Xu, X, Pozharski, E, des Georges, A. Deposit date: 2019-11-05 Release date: 2020-01-22 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly. Proc.Natl.Acad.Sci.USA, 117, 2020
6UZE	Anthrax toxin protective antigen channels bound to edema factor Descriptor: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen Authors: Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. Deposit date: 2019-11-15 Release date: 2020-03-04 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun, 11, 2020
3TEX	Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.7-A resolution Descriptor: CALCIUM ION, Protective antigen Authors: Feld, G.K, Krantz, B.A. Deposit date: 2011-08-15 Release date: 2011-10-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
6UWI	Crystal structure of the Clostridium difficile translocase CDTb Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION Authors: Pozharski, E. Deposit date: 2019-11-05 Release date: 2020-01-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly. Proc.Natl.Acad.Sci.USA, 117, 2020
6VRA	Anthrax octamer prechannel bound to full-length edema factor Descriptor: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen Authors: Zhou, K, Hardenbrook, N.J, Liu, S, Cui, Y.X, Krantz, B.A, Zhou, Z.H. Deposit date: 2020-02-07 Release date: 2020-12-16 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Atomic Structures of Anthrax Prechannel Bound with Full-Length Lethal and Edema Factors. Structure, 28, 2020

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