6K72
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![BU of 6k72 by Molmil](/molmil-images/mine/6k72) | eIF2(aP) - eIF2B complex | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | Authors: | Kashiwagi, K, Yokoyama, T, Ito, T. | Deposit date: | 2019-06-05 | Release date: | 2019-07-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis for eIF2B inhibition in integrated stress response. Science, 364, 2019
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1KK0
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1KK3
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![BU of 1kk3 by Molmil](/molmil-images/mine/1kk3) | Structure of the wild-type large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi complexed with GDP-Mg2+ | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... | Authors: | Schmitt, E, Blanquet, S, Mechulam, Y. | Deposit date: | 2001-12-06 | Release date: | 2002-04-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors. EMBO J., 21, 2002
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6K71
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![BU of 6k71 by Molmil](/molmil-images/mine/6k71) | eIF2 - eIF2B complex | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | Authors: | Kashiwagi, K, Yokoyama, T, Ito, T. | Deposit date: | 2019-06-05 | Release date: | 2019-07-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis for eIF2B inhibition in integrated stress response. Science, 364, 2019
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7QTT
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7QP7
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![BU of 7qp7 by Molmil](/molmil-images/mine/7qp7) | Structure of the human 48S initiation complex in closed state (h48S AUG closed) | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. | Deposit date: | 2022-01-03 | Release date: | 2022-05-11 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
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1PN6
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![BU of 1pn6 by Molmil](/molmil-images/mine/1pn6) | Domain-wise fitting of the crystal structure of T.thermophilus EF-G into the low resolution map of the release complex.Puromycin.EFG.GDPNP of E.coli 70S ribosome. | Descriptor: | Elongation factor G | Authors: | Valle, M, Zavialov, A, Sengupta, J, Rawat, U, Ehrenberg, M, Frank, J. | Deposit date: | 2003-06-12 | Release date: | 2003-07-15 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (10.8 Å) | Cite: | Locking and Unlocking of Ribosomal Motions Cell(Cambridge,Mass.), 114, 2003
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6MIJ
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![BU of 6mij by Molmil](/molmil-images/mine/6mij) | Crystal structure of EF-Tu from Acinetobacter baumannii in complex with Mg2+ and GDP | Descriptor: | Elongation factor Tu, FORMIC ACID, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Stogios, P.J, Evdokimova, E, Tan, K, Di Leo, R, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-09-19 | Release date: | 2018-10-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.955 Å) | Cite: | To be published To Be Published
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1SKQ
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![BU of 1skq by Molmil](/molmil-images/mine/1skq) | The crystal structure of Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Vitagliano, L, Ruggiero, A, Masullo, M, Cantiello, P, Arcari, P, Zagari, A. | Deposit date: | 2004-03-05 | Release date: | 2004-07-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with magnesium and GDP. Biochemistry, 43, 2004
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1U2R
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![BU of 1u2r by Molmil](/molmil-images/mine/1u2r) | Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Jorgensen, R, Yates, S.P, Nilsson, J, Prentice, G.A, Teal, D.J, Merrill, A.R, Andersen, G.R. | Deposit date: | 2004-07-20 | Release date: | 2004-09-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae J.Biol.Chem., 279, 2004
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8XSX
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![BU of 8xsx by Molmil](/molmil-images/mine/8xsx) | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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7ZKI
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![BU of 7zki by Molmil](/molmil-images/mine/7zki) | Cryo-EM structure of aIF1A:aIF5B:Met-tRNAiMet complex from a Pyrococcus abyssi 30S initiation complex | Descriptor: | MAGNESIUM ION, METHIONINE, Met-tRNAiMet, ... | Authors: | Coureux, P.D, Bourgeois, G, Mechulam, Y, Schmitt, E, Kazan, R. | Deposit date: | 2022-04-13 | Release date: | 2022-07-20 | Last modified: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Role of aIF5B in archaeal translation initiation. Nucleic Acids Res., 50, 2022
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7ZJW
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![BU of 7zjw by Molmil](/molmil-images/mine/7zjw) | Rabbit 80S ribosome as it decodes the Sec-UGA codon | Descriptor: | 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ... | Authors: | Hilal, T, Simonovic, M, Spahn, C.M.T. | Deposit date: | 2022-04-12 | Release date: | 2022-10-19 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Science, 376, 2022
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8Y0W
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![BU of 8y0w by Molmil](/molmil-images/mine/8y0w) | dormant ribosome with eIF5A, eEF2 and SERBP1 | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Du, M, Zeng, F. | Deposit date: | 2024-01-23 | Release date: | 2024-02-07 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes. Front Mol Biosci, 11, 2024
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8Y0X
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![BU of 8y0x by Molmil](/molmil-images/mine/8y0x) | Dormant ribosome with SERBP1 | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Du, M, Zeng, F. | Deposit date: | 2024-01-23 | Release date: | 2024-02-07 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes. Front Mol Biosci, 11, 2024
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8Y6O
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![BU of 8y6o by Molmil](/molmil-images/mine/8y6o) | Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R. | Deposit date: | 2024-02-02 | Release date: | 2024-03-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome. Science, 383, 2024
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1TTT
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![BU of 1ttt by Molmil](/molmil-images/mine/1ttt) | Phe-tRNA, elongation factoR EF-TU:GDPNP ternary complex | Descriptor: | MAGNESIUM ION, OF ELONGATION FACTOR TU (EF-TU), PHENYLALANINE, ... | Authors: | Nissen, P, Kjeldgaard, M, Thirup, S, Polekhina, G, Reshetnikova, L, Clark, B.F.C, Nyborg, J. | Deposit date: | 1995-11-16 | Release date: | 1996-12-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog. Science, 270, 1995
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1TUI
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![BU of 1tui by Molmil](/molmil-images/mine/1tui) | INTACT ELONGATION FACTOR TU IN COMPLEX WITH GDP | Descriptor: | ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Polekhina, G, Thirup, S, Kjeldgaard, M, Nissen, P, Lippmann, C, Nyborg, J. | Deposit date: | 1996-05-23 | Release date: | 1997-06-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Helix unwinding in the effector region of elongation factor EF-Tu-GDP. Structure, 4, 1996
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4R71
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![BU of 4r71 by Molmil](/molmil-images/mine/4r71) | Structure of the Qbeta holoenzyme complex in the P1211 crystal form | Descriptor: | 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu, ... | Authors: | Gytz, H, Seweryn, P, Kutlubaeva, Z, Chetverin, A.B, Brodersen, D.E, Knudsen, C.R. | Deposit date: | 2014-08-26 | Release date: | 2015-09-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Structural basis for RNA-genome recognition during bacteriophage Q beta replication. Nucleic Acids Res., 43, 2015
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5O8W
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![BU of 5o8w by Molmil](/molmil-images/mine/5o8w) | CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA | Descriptor: | Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ... | Authors: | Wirth, C, Andersen, G.R, Hunte, C. | Deposit date: | 2017-06-14 | Release date: | 2017-08-23 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A. J. Biol. Chem., 292, 2017
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5O9Z
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4G5G
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![BU of 4g5g by Molmil](/molmil-images/mine/4g5g) | ef-tu (Escherichia coli) complexed with nvp-ldu796 | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Palestrant, D. | Deposit date: | 2012-07-17 | Release date: | 2012-12-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Antibiotic optimization and chemical structure stabilization of thiomuracin A. J.Med.Chem., 55, 2012
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8B6Z
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8BSI
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![BU of 8bsi by Molmil](/molmil-images/mine/8bsi) | Giardia ribosome chimeric hybrid-like GDP+Pi bound state (B1) | Descriptor: | 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ... | Authors: | Majumdar, S, Emmerich, A.G, Sanyal, S. | Deposit date: | 2022-11-25 | Release date: | 2023-03-15 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis. Nucleic Acids Res., 51, 2023
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4FWT
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![BU of 4fwt by Molmil](/molmil-images/mine/4fwt) | Complex structure of viral RNA polymerase form III | Descriptor: | CALCIUM ION, Elongation factor Ts, Elongation factor Tu, ... | Authors: | Takeshita, D, Tomita, K. | Deposit date: | 2012-07-02 | Release date: | 2012-08-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Mechanism for template-independent terminal adenylation activity of Q beta replicase Structure, 20, 2012
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