1JQI
 
 | | Crystal Structure of Rat Short Chain Acyl-CoA Dehydrogenase Complexed With Acetoacetyl-CoA | | Descriptor: | ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, short chain acyl-CoA dehydrogenase | | Authors: | Battaile, K.P, Molin-Case, J, Paschke, R, Wang, M, Bennett, D, Vockley, J, Kim, J.-J.P. | | Deposit date: | 2001-08-07 | | Release date: | 2002-02-13 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystal structure of rat short chain acyl-CoA dehydrogenase complexed with acetoacetyl-CoA: comparison with other acyl-CoA dehydrogenases.
J.Biol.Chem., 277, 2002
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1QB6
 | | BOVINE TRYPSIN 3,3'-[3,5-DIFLUORO-4-METHYL-2, 6-PYRIDINEDIYLBIS(OXY)]BIS(BENZENECARBOXIMIDAMIDE) (ZK-805623) COMPLEX | | Descriptor: | 3,3'-[3,5-DIFLUORO-4-METHYL-2,6-PYRIDYLENEBIS(OXY)]-BIS(BENZENECARBOXIMIDAMIDE), CALCIUM ION, POTASSIUM ION, ... | | Authors: | Whitlow, M. | | Deposit date: | 1999-04-29 | | Release date: | 2000-04-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin.
Acta Crystallogr.,Sect.D, 55, 1999
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1QBO
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1JNJ
 | | NMR solution structure of the human beta2-microglobulin | | Descriptor: | beta2-microglobulin | | Authors: | Verdone, G, Corazza, A, Viglino, P, Pettirossi, F, Giorgetti, S, Mangione, P, Andreola, A, Stoppini, M, Bellotti, V, Esposito, G. | | Deposit date: | 2001-07-24 | | Release date: | 2002-02-27 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | The solution structure of human beta2-microglobulin reveals the prodromes of its amyloid transition.
Protein Sci., 11, 2002
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1AT9
 | | STRUCTURE OF BACTERIORHODOPSIN AT 3.0 ANGSTROM DETERMINED BY ELECTRON CRYSTALLOGRAPHY | | Descriptor: | BACTERIORHODOPSIN, RETINAL | | Authors: | Kimura, Y, Vassylyev, D.G, Miyazawa, A, Kidera, A, Matsushima, M, Mitsuoka, K, Murata, K, Hirai, T, Fujiyoshi, Y. | | Deposit date: | 1997-08-20 | | Release date: | 1998-09-16 | | Last modified: | 2024-06-05 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.8 Å) | | Cite: | Surface of bacteriorhodopsin revealed by high-resolution electron crystallography.
Nature, 389, 1997
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1JXQ
 | | Structure of cleaved, CARD domain deleted Caspase-9 | | Descriptor: | Caspase-9, benzoxycarbonyl-Val-Ala-Asp-fluoromethyl ketone Inhibitor | | Authors: | Renatus, M, Stennicke, H.R, Scott, F.L, Liddington, R.C, Salvesen, G.S. | | Deposit date: | 2001-09-08 | | Release date: | 2001-12-12 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Dimer formation drives the activation of the cell death protease caspase 9.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1OKX
 | | Binding Structure of Elastase Inhibitor Scyptolin A | | Descriptor: | ELASTASE 1, SCYPTOLIN A | | Authors: | Matern, U, Schleberger, C, Jelakovic, S, Weckesser, J, Schulz, G.E. | | Deposit date: | 2003-07-31 | | Release date: | 2003-10-24 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Binding Structure of Elastase Inhibitor Scyptolin A
Chem.Biol., 10, 2003
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1DX5
 | | Crystal structure of the thrombin-thrombomodulin complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FORMIC ACID, ... | | Authors: | Fuentes-Prior, P, Iwanaga, Y, Huber, R, Pagila, R, Rumennik, G, Seto, M, Morser, J, Light, D.R, Bode, W. | | Deposit date: | 1999-12-20 | | Release date: | 2000-04-10 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis for the Anticoagulant Activity of the Thrombin-Thrombomodulin Complex
Nature, 404, 2000
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4JLX
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4JR1
 | | Human procaspase-7 bound to Ac-DEVD-CMK | | Descriptor: | Ac-DEVD-CMK, CHLORIDE ION, Procaspase-7 | | Authors: | Thomsen, N.D, Wells, J.A. | | Deposit date: | 2013-03-20 | | Release date: | 2013-05-08 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.149 Å) | | Cite: | Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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1OS0
 | | Thermolysin with an alpha-amino phosphinic inhibitor | | Descriptor: | CALCIUM ION, DIMETHYL SULFOXIDE, N-{(2R)-3-[(S)-[(1R)-1-amino-2-phenylethyl](hydroxy)phosphoryl]-2-benzylpropanoyl}-L-phenylalanine, ... | | Authors: | Selkti, M, Tomas, A, Prange, T. | | Deposit date: | 2003-03-18 | | Release date: | 2003-03-25 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Interactions of a new alpha-aminophosphinic derivative inside the active site of TLN (thermolysin): a model for zinc-metalloendopeptidase inhibition.
Acta Crystallogr.,Sect.D, 59, 2003
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1OS8
 | | RECOMBINANT STREPTOMYCES GRISEUS TRYPSIN | | Descriptor: | CALCIUM ION, SULFATE ION, trypsin | | Authors: | Page, M.J, Wong, S.L, Hewitt, J, Strynadka, N.C, MacGillivray, R.T. | | Deposit date: | 2003-03-18 | | Release date: | 2003-08-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Engineering the Primary Substrate Specificity of Streptomyces griseus Trypsin.
Biochemistry, 42, 2003
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1QB1
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1QLP
 | | 2.0 ANGSTROM STRUCTURE OF INTACT ALPHA-1-ANTITRYPSIN: A CANONICAL TEMPLATE FOR ACTIVE SERPINS | | Descriptor: | ALPHA-1-ANTITRYPSIN | | Authors: | Elliott, P.R, Pei, X.Y, Dafforn, T, Read, R.J, Carrell, R.W, Lomas, D.A. | | Deposit date: | 1999-09-10 | | Release date: | 1999-09-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Topography of a 2.0 A structure of alpha1-antitrypsin reveals targets for rational drug design to prevent conformational disease.
Protein Sci., 9, 2000
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1QLZ
 | | Human prion protein | | Descriptor: | PRION PROTEIN | | Authors: | Zahn, R, Liu, A, Luhrs, T, Wuthrich, K. | | Deposit date: | 1999-09-20 | | Release date: | 1999-12-16 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | NMR Solution Structure of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
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1LUI
 | | NMR Structures of Itk SH2 domain, Pro287cis isoform, ensemble of 20 low energy structures | | Descriptor: | Tyrosine-protein kinase ITK/TSK | | Authors: | Mallis, R.J, Brazin, K.N, Fulton, B.F, Andreotti, A.M. | | Deposit date: | 2002-05-22 | | Release date: | 2002-11-27 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Structural characterization of a proline-driven conformational switch
within the Itk SH2 domain
Nat.Struct.Biol., 9, 2002
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1LUK
 | | NMR Structure of the Itk SH2 domain, Pro287cis, Energy minimized average structure | | Descriptor: | Tyrosine-protein kinase ITK/TSK | | Authors: | Mallis, R.J, Brazin, K.N, Fulton, B.F, Andreotti, A.H. | | Deposit date: | 2002-05-22 | | Release date: | 2002-11-27 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Structural characterization of a proline-driven conformational switch
within the Itk SH2 domain
Nat.Struct.Biol., 9, 2002
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1XAR
 | | Crystal Structure of a fragment of DC-SIGNR (containing the carbohydrate recognition domain and two repeats of the neck). | | Descriptor: | CD209 antigen-like protein 1, SODIUM ION | | Authors: | Feinberg, H, Guo, Y, Mitchell, D.A, Drickamer, K, Weis, W.I. | | Deposit date: | 2004-08-26 | | Release date: | 2004-11-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Extended Neck Regions Stabilize Tetramers of the Receptors DC-SIGN and DC-SIGNR
J.Biol.Chem., 280, 2005
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1M26
 | | Crystal structure of jacalin-T-antigen complex | | Descriptor: | Jacalin, alpha chain, beta chain, ... | | Authors: | Jeyaprakash, A.A, Rani, P.G, Reddy, G.B, Banumathi, S, Betzel, C, Surolia, A, Vijayan, M. | | Deposit date: | 2002-06-21 | | Release date: | 2002-10-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Crystal structure of the jacalin-T-antigen complex and a
comparative study of lectin-T-antigen complexs
J.Mol.Biol., 321, 2002
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1LUN
 | | NMR Structure of the Itk SH2 domain, Pro287trans, energy minimized average structure | | Descriptor: | Tyrosine-protein kinase ITK/TSK | | Authors: | Mallis, R.J, Brazin, K.N, Fulton, D.B, Andreotti, A.H. | | Deposit date: | 2002-05-22 | | Release date: | 2002-11-27 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Structural characterization of a proline-driven conformational switch
within the Itk SH2 domain
Nat.Struct.Biol., 9, 2002
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4JP8
 | | Crystal structure of Pro-F17H/S324A | | Descriptor: | CALCIUM ION, Tk-subtilisin | | Authors: | Yuzaki, K, You, D.J, Uehara, R, Koga, Y, Kanaya, S. | | Deposit date: | 2013-03-19 | | Release date: | 2014-01-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Increase in activation rate of Pro-Tk-subtilisin by a single nonpolar-to-polar amino acid substitution at the hydrophobic core of the propeptide domain
Protein Sci., 22, 2013
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4JA8
 | | Complex of Mitochondrial Isocitrate Dehydrogenase R140Q Mutant with AGI-6780 Inhibitor | | Descriptor: | 1-[5-(cyclopropylsulfamoyl)-2-thiophen-3-yl-phenyl]-3-[3-(trifluoromethyl)phenyl]urea, CALCIUM ION, GLYCEROL, ... | | Authors: | Wei, W, Chen, L, Wu, M, Jiang, F, Travins, J, Qian, K, DeLaBarre, B. | | Deposit date: | 2013-02-18 | | Release date: | 2013-04-10 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation.
Science, 340, 2013
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2A8X
 | | Crystal Structure of Lipoamide Dehydrogenase from Mycobacterium tuberculosis | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Rajashankar, K.R, Bryk, R, Kniewel, R, Buglino, J.A, Nathan, C.F, Lima, C.D. | | Deposit date: | 2005-07-10 | | Release date: | 2005-08-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis
J.Biol.Chem., 280, 2005
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1DF0
 | | Crystal structure of M-Calpain | | Descriptor: | CALPAIN, M-CALPAIN | | Authors: | Hosfield, C.M, Elce, J.S, Davies, P.L, Jia, Z. | | Deposit date: | 1999-11-16 | | Release date: | 2000-06-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation.
EMBO J., 18, 1999
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1WA9
 | | Crystal Structure of the PAS repeat region of the Drosophila clock protein PERIOD | | Descriptor: | PERIOD CIRCADIAN PROTEIN | | Authors: | Yildiz, O, Doi, M, Yujnovsky, I, Cardone, L, Berndt, A, Hennig, S, Schulze, S, Urbanke, C, Sassone-Corsi, P, Wolf, E. | | Deposit date: | 2004-10-25 | | Release date: | 2005-01-12 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Crystal Structure and Interactions of the Pas Repeat Region of the Drosophila Clock Protein Period
Mol.Cell, 17, 2005
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