1DF0

Crystal structure of M-Calpain

Summary for 1DF0

• Entry DOI: 10.2210/pdb1df0/pdb
• Related: 1AJ5 1ALV 1ALW 1DVI
• Descriptor: M-CALPAIN, CALPAIN (3 entities in total)
• Functional Keywords: cysteine protease, calmodulin, papain, catalytic triad, zymogen activation, c2 domain, protease, zymogen, calpain, hydrolase
• Biological source: Rattus norvegicus (Norway rat); More
• Cellular location: Cytoplasm : Q07009 Q64537
• Total number of polymer chains: 2
• Total formula weight: 101299.02

Authors

Hosfield, C.M.,Elce, J.S.,Davies, P.L.,Jia, Z. (deposition date: 1999-11-16, release date: 2000-06-21, Last modification date: 2024-02-07)

• Primary citation: Hosfield, C.M.,Elce, J.S.,Davies, P.L.,Jia, Z.; Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation.; EMBO J., 18:6880-6889, 1999; PubMed: 10601010; DOI: 10.1093/emboj/18.24.6880

Experimental method

X-RAY DIFFRACTION (2.6 Å)