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4QM6
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BU of 4qm6 by Molmil
Structure of bacterial polynucleotide kinase bound to GTP and RNA
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Metallophosphoesterase, ...
Authors:Das, U, Wang, L.K, Smith, P, Shuman, S.
Deposit date:2014-06-15
Release date:2014-10-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of bacterial polynucleotide kinase in a michaelis complex with nucleoside triphosphate (NTP)-Mg2+ and 5'-OH RNA and a mixed substrate-product complex with NTP-Mg2+ and a 5'-phosphorylated oligonucleotide.
J.Bacteriol., 196, 2014
6HMO
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BU of 6hmo by Molmil
Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7 in complex with the SMN-C5 splicing modifier
Descriptor: 2-(8-fluoranyl-2-methyl-imidazo[1,2-a]pyridin-6-yl)-7-(4-methylpiperazin-1-yl)pyrido[1,2-a]pyrimidin-4-one, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
Authors:Campagne, S, Allain, F.H.
Deposit date:2018-09-12
Release date:2019-08-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis of a small molecule targeting RNA for a specific splicing correction.
Nat.Chem.Biol., 15, 2019
6P7M
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BU of 6p7m by Molmil
Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (1:2 complex)
Descriptor: Cas12a, MAGNESIUM ION, anti-CRISPR VA4, ...
Authors:Knott, G.J, Liu, J.J, Doudna, J.A.
Deposit date:2019-06-06
Release date:2019-08-21
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a.
Elife, 8, 2019
7OGP
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BU of 7ogp by Molmil
Structure of the apo-state of the bacteriophage PhiKZ non-virion RNA polymerase - class including clamp
Descriptor: DNA-directed RNA polymerase, PHIKZ055, PHIKZ068, ...
Authors:de Martin Garrido, N, Lai Wan Loong, Y.T.E, Yakunina, M, Aylett, C.H.S.
Deposit date:2021-05-07
Release date:2021-07-07
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the bacteriophage PhiKZ non-virion RNA polymerase.
Nucleic Acids Res., 49, 2021
6P7N
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BU of 6p7n by Molmil
Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (2:2 complex)
Descriptor: Cas12a, MAGNESIUM ION, anti-CRISPR VA4, ...
Authors:Knott, G.J, Liu, J.J, Doudna, J.A.
Deposit date:2019-06-06
Release date:2019-08-21
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a.
Elife, 8, 2019
1C9S
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BU of 1c9s by Molmil
CRYSTAL STRUCTURE OF A COMPLEX OF TRP RNA-BINDING ATTENUATION PROTEIN WITH A 53-BASE SINGLE STRANDED RNA CONTAINING ELEVEN GAG TRIPLETS SEPARATED BY AU DINUCLEOTIDES
Descriptor: SINGLE STRANDED RNA (55-MER), TRP RNA-BINDING ATTENUATION PROTEIN, TRYPTOPHAN
Authors:Antson, A.A, Dodson, E.J, Dodson, G.G, Greaves, R.B, Chen, X.-P, Gollnick, P.
Deposit date:1999-08-03
Release date:1999-09-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA.
Nature, 401, 1999
2ZM5
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BU of 2zm5 by Molmil
Crystal structure of tRNA modification enzyme MiaA in the complex with tRNA(Phe)
Descriptor: MAGNESIUM ION, tRNA delta(2)-isopentenylpyrophosphate transferase, tRNA(Phe)
Authors:Sakai, J, Yao, M, Chimnaronk, S, Tanaka, I.
Deposit date:2008-04-11
Release date:2009-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Snapshots of dynamics in synthesizing N(6)-isopentenyladenosine at the tRNA anticodon
Biochemistry, 48, 2009
1P0B
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BU of 1p0b by Molmil
Crystal Structure Of tRNA-Guanine Transglycosylase (TGT) From Zymomonas mobilis Complexed With Archaeosine Precursor, Preq0
Descriptor: 2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE, Queuine tRNA-ribosyltransferase, ZINC ION
Authors:Brenk, R, Stubbs, M.T, Heine, A, Reuter, K, Klebe, G.
Deposit date:2003-04-10
Release date:2003-09-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug design
Chembiochem, 4, 2003
7UU4
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BU of 7uu4 by Molmil
Crystal structure of APOBEC3G complex with ssRNA
Descriptor: DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(P*UP*AP*AP*UP*UP*U)-3'), SULFATE ION, ...
Authors:Yang, H, Li, S, Chen, X.S.
Deposit date:2022-04-28
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G.
Nat Commun, 13, 2022
1P0E
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BU of 1p0e by Molmil
CRYSTAL STRUCTURE OF ZYMOMONAS MOBILIS tRNA-GUANINE TRANSGLYCOSYLASE (TGT) COCRYSTALLISED WITH PREQ1 AT PH 5.5
Descriptor: 7-DEAZA-7-AMINOMETHYL-GUANINE, Queuine tRNA-ribosyltransferase, ZINC ION
Authors:Brenk, R, Stubbs, M.T, Heine, A, Reuter, K, Klebe, G.
Deposit date:2003-04-10
Release date:2003-09-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug design
Chembiochem, 4, 2003
2JJQ
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BU of 2jjq by Molmil
The crystal structure of Pyrococcus abyssi tRNA (uracil-54, C5)- methyltransferase in complex with S-adenosyl-L-homocysteine
Descriptor: GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, UNCHARACTERIZED RNA METHYLTRANSFERASE PYRAB10780
Authors:Walbott, H, Leulliot, N, Grosjean, H, Golinelli-Pimpaneau, B.
Deposit date:2008-04-17
Release date:2008-08-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of Pyrococcus Abyssi tRNA (Uracil-54, C5)-Methyltransferase Provides Insights Into its tRNA Specificity.
Nucleic Acids Res., 36, 2008
6R9I
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BU of 6r9i by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module
Descriptor: PAN2-PAN3 deadenylation complex catalytic subunit PAN2
Authors:Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
Deposit date:2019-04-03
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
5TKZ
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BU of 5tkz by Molmil
MEC-8 N-terminal RRM bound to tandem GCAC ligand
Descriptor: DNA (5'-D(*AP*GP*CP*AP*CP*AP*TP*TP*TP*TP*TP*TP*TP*TP*AP*GP*CP*AP*CP*A)-3'), Mec-8 protein
Authors:Soufari, H, Mackereth, C.D.
Deposit date:2016-10-10
Release date:2017-01-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.529 Å)
Cite:Conserved binding of GCAC motifs by MEC-8, couch potato, and the RBPMS protein family.
RNA, 23, 2017
1OZQ
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BU of 1ozq by Molmil
CRYSTAL STRUCTURE OF THE MUTATED TRNA-GUANINE TRANSGLYCOSYLASE (TGT)Y106F COMPLEXED WITH PREQ1
Descriptor: 7-DEAZA-7-AMINOMETHYL-GUANINE, Queuine tRNA-ribosyltransferase, ZINC ION
Authors:Brenk, R, Stubbs, M.T, Heine, A, Reuter, K, Klebe, G.
Deposit date:2003-04-09
Release date:2003-09-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug design
Chembiochem, 4, 2003
7FGI
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BU of 7fgi by Molmil
Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7Gppp-AU
Descriptor: MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ...
Authors:Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H.
Deposit date:2021-07-27
Release date:2022-07-27
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1.
Cell Rep, 40, 2022
5NQI
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BU of 5nqi by Molmil
E.coli 16S rRNA Sarcin-Ricin Loop containing a 5-hydroxymethylcytosine modification
Descriptor: E.Coli 27-mer SRL RNA
Authors:Ennifar, E, Micura, R.
Deposit date:2017-04-20
Release date:2017-07-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (0.851 Å)
Cite:Synthesis, Thermodynamic Properties, and Crystal Structure of RNA Oligonucleotides Containing 5-Hydroxymethylcytosine.
J. Org. Chem., 82, 2017
1C04
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BU of 1c04 by Molmil
IDENTIFICATION OF KNOWN PROTEIN AND RNA STRUCTURES IN A 5 A MAP OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI
Descriptor: 23S RRNA FRAGMENT, RIBOSOMAL PROTEIN L11, RIBOSOMAL PROTEIN L14, ...
Authors:Ban, N, Nissen, P, Capel, M, Moore, P.B, Steitz, T.A.
Deposit date:1999-07-14
Release date:1999-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (5 Å)
Cite:Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit.
Nature, 400, 1999
8FTH
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BU of 8fth by Molmil
Chaetomium thermophilum SETX - NPPC internal deletion
Descriptor: 5'-3' RNA helicase-like protein, ADENOSINE-5'-DIPHOSPHATE
Authors:Williams, R.S, Appel, C.D.
Deposit date:2023-01-12
Release date:2023-10-25
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Sen1 architecture: RNA-DNA hybrid resolution, autoregulation, and insights into SETX inactivation in AOA2.
Mol.Cell, 83, 2023
6BB8
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BU of 6bb8 by Molmil
Crystal Structure of Frequency-Interacting RNA helicase (FRH)
Descriptor: FRQ-interacting RNA helicase
Authors:Morales, Y, Johnson, S.J, Olsen, K.J.
Deposit date:2017-10-17
Release date:2018-08-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structure of frequency-interacting RNA helicase from Neurospora crassa reveals high flexibility in a domain critical for circadian rhythm and RNA surveillance.
PLoS ONE, 13, 2018
7OFZ
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BU of 7ofz by Molmil
Nontypeable Haemophillus influenzae SapA in complex with double stranded RNA
Descriptor: ABC-type transport system, periplasmic component, involved in antimicrobial peptide resistance, ...
Authors:Lukacik, P, Owen, C.D, Nettleship, J.E, Bird, L.E, Owens, R.J, Walsh, M.A.
Deposit date:2021-05-05
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.
Plos One, 16, 2021
1ZE2
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BU of 1ze2 by Molmil
Conformational change of pseudouridine 55 synthase upon its association with RNA substrate
Descriptor: 5'-R(*GP*GP*CP*CP*AP*CP*GP*GP*UP*(FHU)P*CP*GP*AP*AP*UP*CP*CP*GP*UP*GP*GP*C)-3', tRNA pseudouridine synthase B
Authors:Phannachet, K, Huang, R.H.
Deposit date:2005-04-16
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Conformational change of pseudouridine 55 synthase upon its association with RNA substrate
Nucleic Acids Res., 32, 2004
1WSU
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BU of 1wsu by Molmil
C-terminal domain of elongation factor selB complexed with SECIS RNA
Descriptor: 5'-R(*GP*GP*CP*GP*UP*UP*GP*CP*CP*GP*GP*UP*CP*U*GP*GP*CP*AP*AP*CP*GP*CP*C)-3', Selenocysteine-specific elongation factor
Authors:Yoshizawa, S, Rasubala, L, Ose, T, Kohda, D, Fourmy, D, Maenaka, K.
Deposit date:2004-11-11
Release date:2005-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for mRNA recognition by elongation factor SelB
Nat.Struct.Mol.Biol., 12, 2005
1B7F
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BU of 1b7f by Molmil
SXL-LETHAL PROTEIN/RNA COMPLEX
Descriptor: PROTEIN (SXL-LETHAL PROTEIN), RNA (5'-R(P*GP*UP*UP*GP*UP*UP*UP*UP*UP*UP*UP*U)-3')
Authors:Handa, N, Nureki, O, Kurimoto, K, Kim, I, Sakamoto, H, Shimura, Y, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1999-01-23
Release date:1999-05-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein.
Nature, 398, 1999
3EWS
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BU of 3ews by Molmil
Human DEAD-box RNA-helicase DDX19 in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX19B
Authors:Lehtio, l, Karlberg, t, Andersson, j, Arrowsmith, c.h, Berglund, h, Bountra, c, Collins, r, Dahlgren, l.g, Edwards, a.m, Flodin, s, Flores, a, Graslund, s, Hammarstrom, m, Johansson, a, Johansson, i, Kotenyova, t, Moche, m, Nilsson, m.e, Nordlund, p, Nyman, t, Olesen, k, Persson, c, Sagemark, j, Thorsell, a.g, Tresaugues, l, Van den berg, s, Weigelt, j, Welin, m, Wikstrom, m, Wisniewska, m, Schueler, h, Structural Genomics Consortium (SGC)
Deposit date:2008-10-16
Release date:2008-11-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The DEXD/H-box RNA Helicase DDX19 Is Regulated by an {alpha}-Helical Switch.
J.Biol.Chem., 284, 2009
6ASX
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BU of 6asx by Molmil
CryoEM structure of E.coli his pause elongation complex
Descriptor: DNA (32-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Kang, J.Y, Landick, R, Darst, S.A.
Deposit date:2017-08-25
Release date:2018-03-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing.
Mol. Cell, 69, 2018

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数据于2024-07-10公开中

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