6P7M
Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (1:2 complex)
Summary for 6P7M
| Entry DOI | 10.2210/pdb6p7m/pdb |
| EMDB information | 20266 20267 |
| Descriptor | Cas12a, mature crRNA, anti-CRISPR VA4, ... (4 entities in total) |
| Functional Keywords | crispr-cas, anti-crispr, cas12a, cpf1, lbcas12a, acrva4, rna binding protein-rna complex, rna binding protein/rna |
| Biological source | Lachnospiraceae bacterium ND2006 More |
| Total number of polymer chains | 3 |
| Total formula weight | 184666.27 |
| Authors | Knott, G.J.,Liu, J.J.,Doudna, J.A. (deposition date: 2019-06-06, release date: 2019-08-21, Last modification date: 2024-03-20) |
| Primary citation | Knott, G.J.,Cress, B.F.,Liu, J.J.,Thornton, B.W.,Lew, R.J.,Al-Shayeb, B.,Rosenberg, D.J.,Hammel, M.,Adler, B.A.,Lobba, M.J.,Xu, M.,Arkin, A.P.,Fellmann, C.,Doudna, J.A. Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a. Elife, 8:-, 2019 Cited by PubMed: 31397669DOI: 10.7554/eLife.49110 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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