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6P7M

Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (1:2 complex)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cas12apolymer1231144160.61Lachnospiraceae bacterium ND2006
2B
(B)
mature crRNApolymer4012815.61Lachnospiraceae bacterium ND2006
3C
(C)
anti-CRISPR VA4polymer23727641.41UniProt (A0A0U2APF4)Moraxella bovoculiAcrVA4
4D, E
(B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
Sequence modifications
C: 1 - 234 (UniProt: A0A0U2APF4)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight184617.7
Non-Polymers*Number of molecules2
Total formula weight48.6
All*Total formula weight184666.3
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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