PDB: 19129 resultsInfo pagesStatus searchChemie searchBIRD

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6V6R	Crystal Structure of a Bromine Derivatized Self-Assembling DNA Crystal Scaffold with Rhombohedral Symmetry. Descriptor: CACODYLATE ION, DNA (5'-D(*CP*AP*CP*TP*GP*AP*CP*TP*CP*AP*TP*GP*CP*TP*CP*AP*TP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*AP*GP*AP*TP*G)-3'), ... Authors: Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H. Deposit date: 2019-12-05 Release date: 2020-12-09 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail. Angew.Chem.Int.Ed.Engl., 59, 2020
6V5B	Human Drosha and DGCR8 in complex with Primary MicroRNA (MP/RNA complex) - Active state Descriptor: CALCIUM ION, Microprocessor complex subunit DGCR8, Pri-miR-16-2 (78-MER), ... Authors: Partin, A, Zhang, K, Jeong, B, Herrell, E, Li, S, Chiu, W, Nam, Y. Deposit date: 2019-12-04 Release date: 2020-04-08 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA. Mol.Cell, 78, 2020
6LTJ	Structure of nucleosome-bound human BAF complex Descriptor: AT-rich interactive domain-containing protein 1A, Actin, cytoplasmic 1, ... Authors: He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. Deposit date: 2020-01-22 Release date: 2020-02-12 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structure of nucleosome-bound human BAF complex. Science, 367, 2020
6WJK	Crystal Structure of a Self-Assembling DNA Crystal Scaffold with Rhombohedral Symmetry Descriptor: DNA (32-MER), DNA (5'-D(*TP*GP*GP*AP*AP*AP*CP*AP*GP*AP*CP*TP*GP*TP*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(P*AP*GP*CP*AP*TP*GP*A)-3'), ... Authors: Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H. Deposit date: 2020-04-13 Release date: 2021-02-24 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (4.514 Å) Cite: A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail. Angew.Chem.Int.Ed.Engl., 59, 2020
3NP8	Crystal structure of Staphylococcal nuclease variant Delta+PHS L36A at cryogenic temperature Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease Authors: Caro, J.A, Schlessman, J.L, Garcia-Moreno, E.B, Heroux, A. Deposit date: 2010-06-28 Release date: 2011-06-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Cavities determine the pressure unfolding of proteins. Proc.Natl.Acad.Sci.USA, 109, 2012
3NXB	Crystal Structure of the Bromodomain of human CECR2 Descriptor: 1,2-ETHANEDIOL, Cat eye syndrome critical region protein 2 Authors: Filippakopoulos, P, Picaud, S, Keates, T, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2010-07-13 Release date: 2010-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
1W22	Crystal structure of inhibited human HDAC8 Descriptor: HISTONE DEACETYLASE 8, N-HYDROXY-4-(METHYL{[5-(2-PYRIDINYL)-2-THIENYL]SULFONYL}AMINO)BENZAMIDE, POTASSIUM ION, ... Authors: Vannini, A, Volpari, C, Caroli Casavola, E, Di Marco, S. Deposit date: 2004-06-25 Release date: 2004-09-24 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structure of a Eukaryotic Zn-Dependent Histone Deacetylase,Human Hdac8,Complexed with a Hydroxamic Acid Inhibitor Proc.Natl.Acad.Sci.USA, 101, 2004
7K0B	The internal aldimine form of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A with cesium ion at the metal coordination site. A random beta-P270L mutation was inserted during PCR step Descriptor: 1,2-ETHANEDIOL, BICINE, CESIUM ION, ... Authors: Hilario, E, Dunn, M.F, Mueller, L.J. Deposit date: 2020-09-04 Release date: 2021-09-22 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.57 Å) Cite: The internal aldimine form of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A with cesium ion at the metal coordination site. A random beta-P270L mutation was inserted during PCR step. To be Published
3NZU	Structure-based Optimization of Pyrazolo -Pyrimidine and -Pyridine Inhibitors of PI3-Kinase Descriptor: 6-(2H-indazol-4-yl)-1-methyl-N-[3-(methylsulfonyl)propyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Authors: Murray, J.M, Wiesmann, C. Deposit date: 2010-07-16 Release date: 2010-12-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure-based optimization of pyrazolo-pyrimidine and -pyridine inhibitors of PI3-kinase. Bioorg.Med.Chem.Lett., 20, 2010
4EWX	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-04-28 Release date: 2013-05-01 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.201 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
7K5A	The external aldimine form of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A in complex with cesium ion at the metal coordination site. Descriptor: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine, 1,2-ETHANEDIOL, CESIUM ION, ... Authors: Hilario, E, Dunn, M.F, Mueller, L.J. Deposit date: 2020-09-16 Release date: 2021-09-22 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The external aldimine form of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A in complex with cesium ion at the metal coordination site. To be Published
4EIT	Crystal structure of an enoyl-(acyl carrier protein) reductase from Bartonella henselae Descriptor: Enoyl-[acyl-carrier-protein] reductase [NADH] Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-04-05 Release date: 2012-04-18 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of an enoyl-(acyl carrier protein) reductase from Bartonella henselae To be Published
3NZS	Structure-based Optimization of Pyrazolo -Pyrimidine and -Pyridine Inhibitors of PI3-Kinase Descriptor: 6-(1,1-dioxidothiomorpholin-4-yl)-N-(3-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Authors: Murray, J.M, Wiesmann, C. Deposit date: 2010-07-16 Release date: 2010-12-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structure-based optimization of pyrazolo-pyrimidine and -pyridine inhibitors of PI3-kinase. Bioorg.Med.Chem.Lett., 20, 2010
4EXX	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-01 Release date: 2013-05-01 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4EMS	Crystal Structure Analysis of Coniferyl Alcohol 9-O-Methyltransferase from Linum Nodiflorum Descriptor: Coniferyl alcohol 9-O-methyltransferase, GLYCEROL Authors: Wolters, S, Heine, A, Petersen, M. Deposit date: 2012-04-12 Release date: 2013-05-01 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7534 Å) Cite: Structural analysis of coniferyl alcohol 9-O-methyltransferase from Linum nodiflorum reveals a novel active-site environment. Acta Crystallogr.,Sect.D, 69, 2013
4EY1	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-01 Release date: 2013-05-01 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.471 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4EX5	Crystal structure of lysyl-tRNA synthetase LysRS from Burkholderia thailandensis bound to lysine Descriptor: LYSINE, Lysine--tRNA ligase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-04-29 Release date: 2012-05-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms. Sci Rep, 7, 2017
3OA3	Crystal structure of a putative deoxyribose-phosphate aldolase from Coccidioides immitis Descriptor: ACETATE ION, aldolase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-08-04 Release date: 2010-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of an unknown aldolase from Coccidioides immitis To be Published
8IB8	Human TRiC-PhLP2A-actin complex in the closed state Descriptor: ACTB protein (Fragment), Phosducin-like protein 3, T-complex protein 1 subunit alpha, ... Authors: Roh, S.H, Park, J, Kim, H, Lim, S. Deposit date: 2023-02-09 Release date: 2023-12-20 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (4.42 Å) Cite: A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
3NXS	Crystal structure of LAO/AO transport system from Mycobacterium smegmatis bound to GDP Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, LAO/AO transport system ATPase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-07-14 Release date: 2010-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structures of Mycobacterial MeaB and MMAA-like GTPases J.Struct.Funct.Genom., 16, 2015
3NYD	Crystal Structure of Kemp Eliminase HG-2 Complexed with Transition State Analog 5-Nitro Benzotriazole Descriptor: 5-nitro-1H-benzotriazole, ACETATE ION, Endo-1,4-beta-xylanase, ... Authors: Lee, T.M, Privett, H.K, Kaiser, J.T, Mayo, S.L. Deposit date: 2010-07-14 Release date: 2011-06-29 Last modified: 2012-04-25 Method: X-RAY DIFFRACTION (1.23 Å) Cite: Iterative approach to computational enzyme design. Proc.Natl.Acad.Sci.USA, 109, 2012
3OA1	Crystal structure of phosphoprotein/Protein P/Protein M1 residues 69-297 from Rabies virus reveals degradation to C-terminal domain only Descriptor: Phosphoprotein, SULFATE ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-08-04 Release date: 2010-08-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of phosphoprotein/Protein P/Protein M1 residues 69-297 from Rabies virus reveals degradation to C-terminal domain only To be Published
3NPS	Crystal structure of membrane-type serine protease 1 (MT-SP1) in complex with the Fab Inhibitor S4 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, S4 FAB HEAVY CHAIN, ... Authors: Baharuddin, A. Deposit date: 2010-06-29 Release date: 2011-07-06 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: A reverse binding motif that contributes to specific protease inhibition by antibodies. J.Mol.Biol., 415, 2012
3NXW	Crystal structure of Staphylococcal nuclease variant Delta+PHS L125A at cryogenic temperature Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease Authors: Caro, J.A, Schlessman, J.L, Garcia-Moreno, E.B, Heroux, A. Deposit date: 2010-07-14 Release date: 2011-07-20 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Cavities determine the pressure unfolding of proteins. Proc.Natl.Acad.Sci.USA, 109, 2012
3NTN	Crystal Structure of UspA1 head and neck domain from Moraxella catarrhalis Descriptor: CHLORIDE ION, NICKEL (II) ION, SULFATE ION, ... Authors: Conners, R, Zaccai, N, Agnew, C, Burton, N, Brady, R.L. Deposit date: 2010-07-05 Release date: 2011-07-06 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding. Proc.Natl.Acad.Sci.USA, 108, 2011

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