PDB: 10243 resultsInfo pagesStatus searchChemie searchBIRD

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4IAI	X-ray Structure of cAMP dependent protein kinase A in complex with high Ca2+ concentration, ADP and phosphorylated peptide pSP20 Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CARBONATE ION, ... Authors: Gerlits, O, Kovalevsky, A. Deposit date: 2012-12-06 Release date: 2013-06-12 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
4IB3	Structure of cAMP dependent protein kinase A in complex with ADP, phosphorylated peptide pSP20, and no metal Descriptor: ADENOSINE-5'-DIPHOSPHATE, cAMP-dependent protein kinase catalytic subunit alpha, phosphorylated pseudo-substrate peptide pSP20 Authors: Gerlits, O, Kovalevsky, A. Deposit date: 2012-12-07 Release date: 2013-12-11 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer. Biochemistry, 53, 2014
2AYU	The structure of nucleosome assembly protein suggests a mechanism for histone binding and shuttling Descriptor: Nucleosome assembly protein Authors: Park, Y.J, Luger, K. Deposit date: 2005-09-08 Release date: 2006-02-07 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3 Å) Cite: The structure of nucleosome assembly protein 1. Proc.Natl.Acad.Sci.Usa, 103, 2006
4IB1	Structure of cAMP dependent protein kinase A in complex with high K+ concentration, ADP and phosphorylated peptide pSP20 Descriptor: ADENOSINE-5'-DIPHOSPHATE, POTASSIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Gerlits, O, Kovalevsky, A. Deposit date: 2012-12-07 Release date: 2013-12-11 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer. Biochemistry, 53, 2014
4IAD	Low temperature X-ray Structure OF cAMP dependent protein kinase A in complex with high Mg2+ concentration, ADP and phosphorylated peptide pSP20 Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphorylated peptide pSP20, ... Authors: Gerlits, O, Kovalevsky, A. Deposit date: 2012-12-06 Release date: 2013-06-12 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
4IAZ	Structure of cAMP dependent protein kinase A in complex with high Ba2+ concentration, ADP and phosphorylated peptide pSP20 Descriptor: ADENOSINE-5'-DIPHOSPHATE, BARIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Gerlits, O, Kovalevsky, A. Deposit date: 2012-12-07 Release date: 2013-06-12 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
4IB0	X-ray Structure of cAMP dependent protein kinase A in complex with high Na+ concentration, ADP and phosphorylated peptide pSP20 Descriptor: ADENOSINE-5'-DIPHOSPHATE, SODIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Gerlits, O, Kovalevsky, A. Deposit date: 2012-12-07 Release date: 2013-12-11 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer. Biochemistry, 53, 2014
7QJ9	Structure of recombinant human gamma-Tubulin Ring Complex 10-spoked assembly intermediate (spokes 3-12, homogeneous dataset) Descriptor: Gamma-tubulin complex component 2, Gamma-tubulin complex component 3, Gamma-tubulin complex component 4, ... Authors: Zupa, E, Pfeffer, S. Deposit date: 2021-12-16 Release date: 2022-01-26 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (8.1 Å) Cite: Modular assembly of the principal microtubule nucleator gamma-TuRC. Nat Commun, 13, 2022
7QJ6	Structure of recombinant human gamma-Tubulin Ring Complex 10-spoked assembly intermediate (spokes 3-12, substoichiometric spokes 13-14) Descriptor: Gamma-tubulin complex component 2, Gamma-tubulin complex component 3, Gamma-tubulin complex component 4, ... Authors: Zupa, E, Pfeffer, S. Deposit date: 2021-12-16 Release date: 2022-01-26 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (7.8 Å) Cite: Modular assembly of the principal microtubule nucleator gamma-TuRC. Nat Commun, 13, 2022
8DGS	Cryo-EM structure of a RAS/RAF complex (state 1) Descriptor: 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, ... Authors: Eck, M.J, Jeon, H, Park, E, Rawson, S. Deposit date: 2022-06-24 Release date: 2023-07-05 Last modified: 2025-05-14 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Cryo-EM structure of a RAS/RAF recruitment complex. Nat Commun, 14, 2023
8DGT	Cryo-EM structure of a RAS/RAF complex (state 2) Descriptor: 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, ... Authors: Eck, M.J, Jeon, H, Park, E, Rawson, S. Deposit date: 2022-06-24 Release date: 2023-07-05 Last modified: 2025-05-14 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Cryo-EM structure of a RAS/RAF recruitment complex. Nat Commun, 14, 2023
8YD8	Structure of FADD/Caspase-8/cFLIP death effector domain assembly Descriptor: CASP8 and FADD-like apoptosis regulator subunit p43, Caspase-8, FAS-associated death domain protein Authors: Lin, S.-C, Yang, C.-Y. Deposit date: 2024-02-19 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis. Nat Commun, 15, 2024
8YD7	Structure of FADD/Caspase-8/cFLIP death effector domain assembly Descriptor: CASP8 and FADD-like apoptosis regulator subunit p12, Caspase-8, FAS-associated death domain protein, ... Authors: Lin, S.-C, Yang, C.-Y. Deposit date: 2024-02-19 Release date: 2024-05-15 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.32 Å) Cite: Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis. Nat Commun, 15, 2024
8YBX	Structure of the FADD/Caspase-8/cFLIP death effector domain assembly Descriptor: CASP8 and FADD-like apoptosis regulator subunit p43, Caspase-8 subunit p10, FAS-associated death domain protein Authors: Lin, S.-C, Yang, C.-Y. Deposit date: 2024-02-16 Release date: 2024-05-15 Method: ELECTRON MICROSCOPY (3.68 Å) Cite: Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis. Nat Commun, 15, 2024
4AYA	Crystal structure of ID2 HLH homodimer at 2.1A resolution Descriptor: ACETATE ION, DNA-BINDING PROTEIN INHIBITOR ID-2, POTASSIUM ION Authors: Wong, M.V, Jiang, S, Palasingam, P, Kolatkar, P.R. Deposit date: 2012-06-19 Release date: 2012-11-14 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.103 Å) Cite: A Divalent Ion is Crucial in the Structure and Dominant-Negative Function of Id Proteins, a Class of Helix-Loop-Helix Transcription Regulators. Plos One, 7, 2012
4MD9	Crystal Structure of symmetric CK2 holoenzyme with mutated alpha subunit (F121E truncated at aa 336) Descriptor: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION Authors: Lolli, G, Ranchio, A, Battistutta, R. Deposit date: 2013-08-22 Release date: 2013-11-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Active Form of the Protein Kinase CK2 alpha 2 beta 2 Holoenzyme Is a Strong Complex with Symmetric Architecture. Acs Chem.Biol., 9, 2014
8P81	Crystal structure of human Cdk12/Cyclin K in complex with inhibitor SR-4835 Descriptor: Cyclin-K, Cyclin-dependent kinase 12, ~{N}-[[5,6-bis(chloranyl)-1~{H}-benzimidazol-2-yl]methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine Authors: Anand, K, Schmitz, M, Geyer, M. Deposit date: 2023-05-31 Release date: 2023-11-22 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.68 Å) Cite: The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation. J.Biol.Chem., 300, 2023
2MEZ	Flexible anchoring of archaeal MBF1 on ribosomes suggests role as recruitment factor Descriptor: Multiprotein Bridging Factor (MBP-like) Authors: Launay, H, Blombarch, F, Camilloni, C, Vendruscolo, M, van des Oost, J, Christodoulou, J. Deposit date: 2013-10-03 Release date: 2014-06-25 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Archaeal MBF1 binds to 30S and 70S ribosomes via its helix-turn-helix domain. Biochem.J., 462, 2014
5ZHX	Crystal structure of SmgGDS-558 and farnesylated RhoA complex Descriptor: FARNESYL, Rap1 GTPase-GDP dissociation stimulator 1, Transforming protein RhoA Authors: Shimizu, H, Toma-Fukai, S, Shimizu, T. Deposit date: 2018-03-13 Release date: 2018-09-05 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.5 Å) Cite: GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4IL1	Crystal Structure of the Rat Calcineurin Descriptor: CALCIUM ION, Calmodulin, Calcineurin subunit B type 1, ... Authors: Ye, Q, Faucher, F, Jia, Z. Deposit date: 2012-12-28 Release date: 2013-10-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis of calcineurin activation by calmodulin. Cell Signal, 25, 2013
5UQ3	Crystal structure of human Cdk2-Spy1-P27 ternary complex Descriptor: Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B, Speedy protein A Authors: McGrath, D.A, Tripathi, S.M, Rubin, S.M. Deposit date: 2017-02-06 Release date: 2017-07-05 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins. EMBO J., 36, 2017
5BQD	Crystal Structure of TBX5 (1-239) Dimer Descriptor: MAGNESIUM ION, T-box transcription factor TBX5 Authors: Pradhan, L, Gopal, S, Patel, A, Kasahara, H, Nam, H.J. Deposit date: 2015-05-28 Release date: 2016-03-16 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.583 Å) Cite: Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5. Biochemistry, 55, 2016
4IAK	Low temperature X-ray structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20 Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBONATE ION, STRONTIUM ION, ... Authors: Gerlits, O, Kovalevsky, A. Deposit date: 2012-12-06 Release date: 2013-06-12 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
4IAY	Room temperature X-ray Structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20 Descriptor: ADENOSINE-5'-DIPHOSPHATE, STRONTIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Gerlits, O, Kovalevsky, A. Deposit date: 2012-12-07 Release date: 2013-06-12 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
1PFL	REFINED SOLUTION STRUCTURE OF HUMAN PROFILIN I Descriptor: PROFILIN I Authors: Metzler, W.J, Farmer II, B.T, Constantine, K.L, Friedrichs, M.S, Lavoie, T, Mueller, L. Deposit date: 1994-12-12 Release date: 1995-03-31 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Refined solution structure of human profilin I. Protein Sci., 4, 1995

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