4IB3

Structure of cAMP dependent protein kinase A in complex with ADP, phosphorylated peptide pSP20, and no metal

Summary for 4IB3

• Entry DOI: 10.2210/pdb4ib3/pdb
• Related: 4IAC 4IAD 4IAF 4IAI 4IAK 4IAY 4IAZ 4IB0 4IB1
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, phosphorylated pseudo-substrate peptide pSP20, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: kinase enzyme, phosphotransfer, phosphorylated, transferase-peptide complex, transferase/peptide
• Biological source: Mus musculus (mouse); More
• Cellular location: Cytoplasm. Isoform 2: Cell projection, cilium, flagellum (By similarity): P05132
• Total number of polymer chains: 2
• Total formula weight: 44272.74

Authors

Gerlits, O.,Kovalevsky, A. (deposition date: 2012-12-07, release date: 2013-12-11, Last modification date: 2014-05-28)

• Primary citation: Gerlits, O.,Das, A.,Keshwani, M.M.,Taylor, S.,Waltman, M.J.,Langan, P.,Heller, W.T.,Kovalevsky, A.; Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer.; Biochemistry, 53:3179-3186, 2014; PubMed: 24786636; DOI: 10.1021/bi5000965

Experimental method

X-RAY DIFFRACTION (2.2 Å)