4IAI
X-ray Structure of cAMP dependent protein kinase A in complex with high Ca2+ concentration, ADP and phosphorylated peptide pSP20
Summary for 4IAI
Entry DOI | 10.2210/pdb4iai/pdb |
Related | 4IAC 4IAD 4IAF 4IAK 4IAY 4IAZ 4IB0 4IB1 4IB3 |
Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, phosphorylated pseudo-substrate peptide pSP20, CALCIUM ION, ... (7 entities in total) |
Functional Keywords | kinase enzyme, phosphotransfer, phosphorylation, transferase-peptide complex, transferase/peptide |
Biological source | Mus musculus (mouse) More |
Cellular location | Cytoplasm. Isoform 2: Cell projection, cilium, flagellum (By similarity): P05132 |
Total number of polymer chains | 2 |
Total formula weight | 44519.02 |
Authors | Gerlits, O.,Kovalevsky, A. (deposition date: 2012-12-06, release date: 2013-06-12, Last modification date: 2013-12-18) |
Primary citation | Gerlits, O.,Waltman, M.J.,Taylor, S.,Langan, P.,Kovalevsky, A. Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52:3721-3727, 2013 Cited by PubMed: 23672593DOI: 10.1021/bi400066a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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