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4E2K
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BU of 4e2k by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain
Descriptor: BENZAMIDINE, DNA primase
Authors:Rymer, R.U, Solorio, F.A, Clement, C, Corn, J.E, Wang, J.D, Berger, J.M.
Deposit date:2012-03-08
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EBE
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BU of 4ebe by Molmil
Conformationally Restrained North-methanocarba-2'-deoxyadenosine Corrects the Error-Prone Nature of Human DNA Polymerase Iota
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(P*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(P*CP*TP*GP*GP*GP*TP*CP*CP*T)-3', ...
Authors:Eoff, R.L, Ketkar, A, Banerjee, S.
Deposit date:2012-03-23
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Nucleotide-Analogue-Induced Gain of Function Corrects the Error-Prone Nature of Human DNA Polymerase iota.
J.Am.Chem.Soc., 134, 2012
4EDK
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BU of 4edk by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to GTP and Manganese
Descriptor: BENZAMIDINE, DNA primase, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
Deposit date:2012-03-27
Release date:2012-07-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EE1
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BU of 4ee1 by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to CTP and Manganese
Descriptor: BENZAMIDINE, CYTIDINE-5'-TRIPHOSPHATE, DNA primase, ...
Authors:Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
Deposit date:2012-03-28
Release date:2012-07-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
3L2P
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BU of 3l2p by Molmil
Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching Between Two DNA Bound States
Descriptor: 5'-D(*GP*CP*CP*AP*GP*TP*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*CP*CP*G)-3', 5'-D(*GP*TP*CP*GP*GP*AP*CP*TP*G)-3', 5'-D(P*CP*GP*GP*GP*AP*TP*GP*CP*GP*TP*C)-3', ...
Authors:Cotner-Gohara, E.A, Kim, I.K, Hammel, M, Tainer, J.A, Tomkinson, A, Ellenberger, T.
Deposit date:2009-12-15
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching between Two DNA-Bound States.
Biochemistry, 49, 2010
8IFK
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BU of 8ifk by Molmil
Cryo-EM structure of monomeric SPARTA gRNA-ssDNA target complex
Descriptor: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
Authors:Zhang, J.T, Jia, N.
Deposit date:2023-02-18
Release date:2024-01-17
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
2GLO
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BU of 2glo by Molmil
Solution structure of the Brinker DNA binding domain in complex with the omb enhancer
Descriptor: 5'-D(*GP*TP*TP*GP*AP*CP*GP*CP*CP*TP*CP*A)-3', 5'-D(*TP*GP*AP*GP*GP*CP*GP*TP*CP*AP*AP*C)-3', brinker CG9653-PA
Authors:Cordier, F, Hartmann, B, Rogowski, M, Affolter, M, Grzesiek, S.
Deposit date:2006-04-05
Release date:2006-08-29
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:DNA recognition by the brinker repressor - an extreme case of coupling between binding and folding
J.Mol.Biol., 361, 2006
102D
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BU of 102d by Molmil
SEQUENCE-DEPENDENT DRUG BINDING TO THE MINOR GROOVE OF DNA: THE CRYSTAL STRUCTURE OF THE DNA DODECAMER D(CGCAAATTTGCG)2 COMPLEXED WITH PROPAMIDINE
Descriptor: 1,3-BIS(AMIDINOPHENOXY)PROPANE, DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3')
Authors:Nunn, C.M, Neidle, S.
Deposit date:1994-12-15
Release date:1995-02-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sequence-dependent drug binding to the minor groove of DNA: crystal structure of the DNA dodecamer d(CGCAAATTTGCG)2 complexed with propamidine.
J.Med.Chem., 38, 1995
4EBD
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BU of 4ebd by Molmil
Conformationally Restrained North-methanocarba-2'-deoxyadenosine Corrects the Error-Prone Nature of Human DNA Polymerase Iota
Descriptor: 5'-D(P*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(P*CP*TP*GP*GP*GP*TP*CP*CP*T)-3', CALCIUM ION, ...
Authors:Eoff, R.L, Ketkar, A, Banerjee, S.
Deposit date:2012-03-23
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.571 Å)
Cite:A Nucleotide-Analogue-Induced Gain of Function Corrects the Error-Prone Nature of Human DNA Polymerase iota.
J.Am.Chem.Soc., 134, 2012
4EDG
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BU of 4edg by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to ATP and Manganese
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, BENZAMIDINE, DNA primase, ...
Authors:Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
Deposit date:2012-03-27
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
6OWN
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BU of 6own by Molmil
Crystal structure of Msm DnaB1 intein splicing domain bound with zinc
Descriptor: Replicative DNA helicase, ZINC ION
Authors:Bacot-Davis, V.R, Belfort, M, Lennon, C.
Deposit date:2019-05-10
Release date:2020-05-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Conditional DnaB Protein Splicing Is Reversibly Inhibited by Zinc in Mycobacteria.
Mbio, 11, 2020
5TVP
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BU of 5tvp by Molmil
SUMO2 bound to Mouse Tdp2 catalytic domain with a 5'-phosphorylated DNA ternary complex
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), ...
Authors:Schellenberg, M.J, Williams, R.S.
Deposit date:2016-11-09
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links.
Science, 357, 2017
2HPI
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BU of 2hpi by Molmil
Eubacterial and Eukaryotic Replicative DNA Polymerases are not Homologous: X-ray Structure of DNA Polymerase III
Descriptor: CHLORIDE ION, DNA polymerase III alpha subunit, MAGNESIUM ION, ...
Authors:Bailey, S, Wing, R.A, Steitz, T.A.
Deposit date:2006-07-17
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases.
Cell(Cambridge,Mass.), 126, 2006
1EYG
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BU of 1eyg by Molmil
Crystal structure of chymotryptic fragment of E. coli ssb bound to two 35-mer single strand DNAS
Descriptor: SINGLE STRANDED 28-MER OF D(C), SINGLE-STRAND DNA-BINDING PROTEIN
Authors:Raghunathan, S, Waksman, G.
Deposit date:2000-05-06
Release date:2000-08-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the DNA binding domain of E. coli SSB bound to ssDNA.
Nat.Struct.Biol., 7, 2000
4EDV
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BU of 4edv by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to pppGpp and Manganese
Descriptor: BENZAMIDINE, DNA primase, MANGANESE (II) ION, ...
Authors:Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
Deposit date:2012-03-27
Release date:2012-07-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EBC
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BU of 4ebc by Molmil
Conformationally Restrained North-methanocarba-2'-deoxyadenosine Corrects the Error-Prone Nature of Human DNA Polymerase Iota
Descriptor: 5'-D(P*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(P*CP*TP*GP*GP*GP*TP*CP*CP*T)-3', CALCIUM ION, ...
Authors:Eoff, R.L, Ketkar, A, Banerjee, S.
Deposit date:2012-03-23
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:A Nucleotide-Analogue-Induced Gain of Function Corrects the Error-Prone Nature of Human DNA Polymerase iota.
J.Am.Chem.Soc., 134, 2012
4EDT
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BU of 4edt by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to ppGpp and Manganese
Descriptor: BENZAMIDINE, DNA primase, GUANOSINE-5',3'-TETRAPHOSPHATE, ...
Authors:Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
Deposit date:2012-03-27
Release date:2012-07-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDR
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BU of 4edr by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to UTP and Manganese
Descriptor: BENZAMIDINE, DNA primase, MANGANESE (II) ION, ...
Authors:Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
Deposit date:2012-03-27
Release date:2012-07-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
1FIU
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BU of 1fiu by Molmil
TETRAMERIC RESTRICTION ENDONUCLEASE NGOMIV IN COMPLEX WITH CLEAVED DNA
Descriptor: ACETIC ACID, DNA (5'-D(*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*CP*GP*C)-3'), ...
Authors:Deibert, M, Grazulis, S, Sasnauskas, G, Siksnys, V, Huber, R.
Deposit date:2000-08-07
Release date:2001-02-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA.
Nat.Struct.Biol., 7, 2000
6I1K
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BU of 6i1k by Molmil
Crystal structure of catalytically inactive FnCas12a in complex with a crRNA guide and a dsDNA target
Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas12a, DNA non-target strand (33-MER), ...
Authors:Jinek, M, Swarts, D.C.
Deposit date:2018-10-29
Release date:2019-01-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.
Mol. Cell, 73, 2019
8IFM
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BU of 8ifm by Molmil
Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 2
Descriptor: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
Authors:Zhang, J.T, Jia, N.
Deposit date:2023-02-18
Release date:2024-01-17
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
8IFL
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BU of 8ifl by Molmil
Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 1
Descriptor: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
Authors:Zhang, J.T, Jia, N.
Deposit date:2023-02-18
Release date:2024-01-17
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
4E0P
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BU of 4e0p by Molmil
Protelomerase tela covalently complexed with substrate DNA
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*TP*AP*AP*TP*AP*AP*CP*AP*AP*TP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*GP*AP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*AP*TP*G)-3'), ...
Authors:Shi, K, Aihara, H.
Deposit date:2012-03-05
Release date:2013-02-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An enzyme-catalyzed multistep DNA refolding mechanism in hairpin telomere formation.
Plos Biol., 11, 2013
4E0J
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BU of 4e0j by Molmil
Protelomerase tela R255A mutant complexed with DNA hairpin product
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*AP*TP*AP*AP*TP*AP*AP*CP*AP*AP*TP*A)-3'), DNA (5'-D(*TP*CP*AP*TP*GP*AP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*AP*TP*G)-3'), ...
Authors:Shi, K, Aihara, H.
Deposit date:2012-03-04
Release date:2013-02-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:An enzyme-catalyzed multistep DNA refolding mechanism in hairpin telomere formation.
Plos Biol., 11, 2013
7LMM
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BU of 7lmm by Molmil
Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2
Descriptor: DNA (cytosine-5)-methyltransferase 1,DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION
Authors:Ren, W, Song, J.
Deposit date:2021-02-05
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Nat Commun, 12, 2021

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数据于2024-08-28公开中

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