8IFM

Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 2

Summary for 8IFM

Entry DOI	10.2210/pdb8ifm/pdb
EMDB information	35421
Descriptor	TIR domain-containing protein, Piwi domain-containing protein, guide RNA, ... (5 entities in total)
Functional Keywords	rna binding protein-rna-dna complex, rna binding protein/rna/dna
Biological source	Thermoflavifilum thermophilum More
Total number of polymer chains	16
Total formula weight	503703.49
Authors	Zhang, J.T.,Jia, N. (deposition date: 2023-02-18, release date: 2024-01-17, Last modification date: 2024-04-10)
Primary citation	Zhang, J.T.,Wei, X.Y.,Cui, N.,Tian, R.,Jia, N. Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system. Nat.Chem.Biol., 20:503-511, 2024 Cited by PubMed: 37932528 DOI: 10.1038/s41589-023-01479-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.92 Å)

Structure validation