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6HIW
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BU of 6hiw by Molmil
Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the complete small mitoribosomal subunit in complex with mt-IF-3
Descriptor: 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ramrath, D, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2018-08-31
Release date:2018-09-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Science, 362, 2018
6HWR
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BU of 6hwr by Molmil
Red kidney bean purple acid phosphatase in complex with adenosine divanadate
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Feder, D, Gahan, L.R, McGeary, R.P, Guddat, L.W, Schenk, G.
Deposit date:2018-10-13
Release date:2019-04-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Binding Mode of an ADP Analogue to a Metallohydrolase Mimics the Likely Transition State.
Chembiochem, 20, 2019
7MT0
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BU of 7mt0 by Molmil
Structure of the adeno-associated virus 9 capsid at pH 7.4
Descriptor: Capsid protein VP1
Authors:Penzes, J.J, Chipman, P, Bhattacharya, N, Zeher, A, Huang, R, McKenna, R, Agbandje-McKenna, M.
Deposit date:2021-05-12
Release date:2021-06-02
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Adeno-associated Virus 9 Structural Rearrangements Induced by Endosomal Trafficking pH and Glycan Attachment.
J.Virol., 95, 2021
6TZU
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BU of 6tzu by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, N84A mutant with pyruvate bound in the active site
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Majdi Yazdi, M, Lehnert, C, Palmer, D.R.J, Sanders, D.A.R.
Deposit date:2019-08-13
Release date:2019-12-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Asparagine-84, a regulatory allosteric site residue, helps maintain the quaternary structure of Campylobacter jejuni dihydrodipicolinate synthase.
J.Struct.Biol., 209, 2020
7MTZ
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BU of 7mtz by Molmil
Structure of the adeno-associated virus 9 capsid at pH pH 7.4 in complex with terminal galactose
Descriptor: Capsid protein VP1, beta-D-galactopyranose
Authors:Penzes, J.J, Chipman, P, Bhattacharya, N, Zeher, A, Huang, R, McKenna, R, Agbandje-McKenna, M.
Deposit date:2021-05-14
Release date:2021-06-09
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.43 Å)
Cite:Adeno-associated Virus 9 Structural Rearrangements Induced by Endosomal Trafficking pH and Glycan Attachment.
J.Virol., 95, 2021
7MUA
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BU of 7mua by Molmil
Structure of the adeno-associated virus 9 capsid at pH pH 5.5 in complex with terminal galactose
Descriptor: Capsid protein VP1, beta-D-galactopyranose
Authors:Penzes, J.J, Chipman, P, Bhattacharya, N, Zeher, A, Huang, R, McKenna, R, Agbandje-McKenna, M.
Deposit date:2021-05-14
Release date:2021-06-09
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Adeno-associated Virus 9 Structural Rearrangements Induced by Endosomal Trafficking pH and Glycan Attachment.
J.Virol., 95, 2021
6TZL
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BU of 6tzl by Molmil
The structure of the Streptococcus gordonii surface protein SspB in complex with TEV peptide provides clues to the adherence of oral streptococcal adherence to salivary agglutinin
Descriptor: SULFATE ION, Surface protein adhesin
Authors:Schormann, N, Deivanayagam, C.
Deposit date:2019-08-12
Release date:2020-08-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The structure of the Streptococcus gordonii surface protein SspB in complex with TEV peptide provides clues to the adherence of oral streptococcal adherence to salivary agglutinin
To Be Published
6I31
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BU of 6i31 by Molmil
Crystal structure of the tick chemokine-binding protein Evasin-3
Descriptor: CADMIUM ION, Evasin-3
Authors:Dias, J.M, Shaw, J.P.
Deposit date:2018-11-02
Release date:2019-06-19
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
J.Biol.Chem., 294, 2019
7MTG
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BU of 7mtg by Molmil
Structure of the adeno-associated virus 9 capsid at pH 6.0
Descriptor: Capsid protein VP1
Authors:Penzes, J.J, Chipman, P, Bhattacharya, N, Zeher, A, Huang, R, McKenna, R, Agbandje-McKenna, M.
Deposit date:2021-05-13
Release date:2021-07-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Adeno-associated Virus 9 Structural Rearrangements Induced by Endosomal Trafficking pH and Glycan Attachment.
J.Virol., 95, 2021
7MTP
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BU of 7mtp by Molmil
Structure of the adeno-associated virus 9 capsid at pH 5.5
Descriptor: Capsid protein VP1
Authors:Penzes, J.J, Chipman, P, Bhattacharya, N, Zeher, A, Huang, R, McKenna, R, Agbandje-McKenna, M.
Deposit date:2021-05-13
Release date:2021-07-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Adeno-associated Virus 9 Structural Rearrangements Induced by Endosomal Trafficking pH and Glycan Attachment.
J.Virol., 95, 2021
7MTW
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BU of 7mtw by Molmil
Structure of the adeno-associated virus 9 capsid at pH 4.0
Descriptor: Capsid protein VP1
Authors:Penzes, J.J, Chipman, P, Bhattacharya, N, Zeher, A, Huang, R, McKenna, R, Agbandje-McKenna, M.
Deposit date:2021-05-13
Release date:2021-07-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Adeno-associated Virus 9 Structural Rearrangements Induced by Endosomal Trafficking pH and Glycan Attachment.
J.Virol., 95, 2021
2LVH
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BU of 2lvh by Molmil
Solution structure of the zinc finger AFV1p06 protein from the hyperthermophilic archaeal virus AFV1
Descriptor: Putative zinc finger protein ORF59a, ZINC ION
Authors:Guilliere, F, Sezonov, G, Prangishvili, D, Delepierre, M, Guijarro, J.
Deposit date:2012-07-05
Release date:2013-01-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of an archaeal DNA binding protein with an eukaryotic zinc finger fold.
Plos One, 8, 2013
6I5T
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BU of 6i5t by Molmil
Cryo-EM informed directed evolution of Nitrilase 4 leads to a change in quaternary structure.
Descriptor: Bifunctional nitrilase/nitrile hydratase NIT4
Authors:Mulelu, A.E, Woodward, J.D.
Deposit date:2018-11-14
Release date:2019-11-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM informed directed evolution of nitrilase 4 leads to a change in quaternary structure.
To Be Published
7XFX
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BU of 7xfx by Molmil
Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.28 A resolution.
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
Authors:Maurya, A, Singh, P.K, Viswanathan, V, Sharma, P, Sharma, S, Singh, T.P.
Deposit date:2022-04-02
Release date:2022-05-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.28 A resolution.
To Be Published
7XFY
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BU of 7xfy by Molmil
Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.67 A resolution.
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
Authors:Maurya, A, Singh, P.K, Viswanathan, V, Sharma, P, Sharma, S, Singh, T.P.
Deposit date:2022-04-02
Release date:2022-05-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.67 A resolution.
To Be Published
6V8Z
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BU of 6v8z by Molmil
VRC03 and 10-1074 Bound BG505 F14 HIV-1 SOSIP Envelope Trimer Structure
Descriptor: 10-1074 Fab Heavy Chain, 10-1074 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Henderson, R, Acharya, P.
Deposit date:2019-12-12
Release date:2020-02-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements.
Nat Commun, 11, 2020
6I5U
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BU of 6i5u by Molmil
Cryo-EM informed directed evolution of Nitrilase 4 leads to a change in quaternary structure.
Descriptor: Bifunctional nitrilase/nitrile hydratase NIT4
Authors:Mulelu, A.E, Woodward, J.D.
Deposit date:2018-11-14
Release date:2019-11-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM informed directed evolution of nitrilase 4 leads to a change in quaternary structure.
To Be Published
6UWI
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BU of 6uwi by Molmil
Crystal structure of the Clostridium difficile translocase CDTb
Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION
Authors:Pozharski, E.
Deposit date:2019-11-05
Release date:2020-01-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly.
Proc.Natl.Acad.Sci.USA, 117, 2020
7MGJ
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BU of 7mgj by Molmil
TNNI3K complexed with N-methyl-4-(4-(3-(3-(trifluoromethyl) phenyl) ureido) phenoxy)picolinamide
Descriptor: N-methyl-4-[4-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]pyridine-2-carboxamide, Serine/threonine-protein kinase TNNI3K
Authors:Shewchuk, L.M.
Deposit date:2021-04-12
Release date:2021-11-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38 alpha , and B-Raf.
J.Med.Chem., 64, 2021
7MGK
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BU of 7mgk by Molmil
TNNI3K complexed with 1-(3,5-dichloro-4-((6-(methylamino)pyrimidin-4-yl)oxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
Descriptor: N-(3,5-dichloro-4-{[6-(methylamino)pyrimidin-4-yl]oxy}phenyl)-N'-[3-(trifluoromethyl)phenyl]urea, Serine/threonine-protein kinase TNNI3K
Authors:Shewchuk, L.M.
Deposit date:2021-04-12
Release date:2021-11-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38 alpha , and B-Raf.
J.Med.Chem., 64, 2021
6V0N
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BU of 6v0n by Molmil
PRMT5 bound to PBM peptide from Riok1
Descriptor: Methylosome protein 50, Protein arginine N-methyltransferase 5, Riok1 PBM peptide, ...
Authors:McMIllan, B.J, Raymond, D.D.
Deposit date:2019-11-19
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Molecular basis for substrate recruitment to the PRMT5 methylosome.
Mol.Cell, 81, 2021
8G1P
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BU of 8g1p by Molmil
Co-crystal structure of Compound 11 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB
Descriptor: (2~{S},4~{R})-~{N}-[[2-[2-[4-[[4-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazin-1-yl]methyl]phenyl]ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ...
Authors:Ghimire Rijal, S, Wurz, R.P, Vaish, A.
Deposit date:2023-02-02
Release date:2023-07-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation.
Nat Commun, 14, 2023
8G1Q
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BU of 8g1q by Molmil
Co-crystal structure of Compound 1 in complex with the bromodomain of human SMARCA4 and pVHL:ElonginC:ElonginB
Descriptor: DI(HYDROXYETHYL)ETHER, Elongin-B, Elongin-C, ...
Authors:Ghimire Rijal, S, Wurz, R.P, Vaish, A.
Deposit date:2023-02-02
Release date:2023-07-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.73 Å)
Cite:Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation.
Nat Commun, 14, 2023
7NAY
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BU of 7nay by Molmil
Crystal structure of lactate dehydrogenase from Selenomonas ruminantium with NADH.
Descriptor: 1,2-ETHANEDIOL, BORIC ACID, L-lactate dehydrogenase, ...
Authors:Bertrand, Q, Robin, A, Girard, E, Madern, D.
Deposit date:2021-01-25
Release date:2021-02-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete allosteric regulation acquisition in the super family of lactate and malate dehydrogenases.
J.Struct.Biol., 215, 2023
6UWO
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BU of 6uwo by Molmil
Crystal structure of receptor binding domain 2 from Clostridium difficile translocase CDTb
Descriptor: ADP-ribosyltransferase binding component
Authors:Pozharski, E.
Deposit date:2019-11-05
Release date:2020-01-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly.
Proc.Natl.Acad.Sci.USA, 117, 2020

224931

数据于2024-09-11公开中

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