6V0N

PRMT5 bound to PBM peptide from Riok1

Summary for 6V0N

Entry DOI	10.2210/pdb6v0n/pdb
Descriptor	Protein arginine N-methyltransferase 5, Methylosome protein 50, Riok1 PBM peptide, ... (5 entities in total)
Functional Keywords	methylation, epigenetics, splicing, sdma, transferase-splicing complex, transferase/splicing
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	111222.55
Authors	McMIllan, B.J.,Raymond, D.D. (deposition date: 2019-11-19, release date: 2020-08-26, Last modification date: 2023-10-11)
Primary citation	Mulvaney, K.M.,Blomquist, C.,Acharya, N.,Li, R.,Ranaghan, M.J.,O'Keefe, M.,Rodriguez, D.J.,Young, M.J.,Kesar, D.,Pal, D.,Stokes, M.,Nelson, A.J.,Jain, S.S.,Yang, A.,Mullin-Bernstein, Z.,Columbus, J.,Bozal, F.K.,Skepner, A.,Raymond, D.,LaRussa, S.,McKinney, D.C.,Freyzon, Y.,Baidi, Y.,Porter, D.,Aguirre, A.J.,Ianari, A.,McMillan, B.,Sellers, W.R. Molecular basis for substrate recruitment to the PRMT5 methylosome. Mol.Cell, 81:3481-, 2021 Cited by PubMed: 34358446 DOI: 10.1016/j.molcel.2021.07.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.11 Å)

Structure validation