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2P6R
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BU of 2p6r by Molmil
Crystal structure of superfamily 2 helicase Hel308 in complex with unwound DNA
Descriptor: 25-MER, 5'-D(*CP*TP*AP*GP*AP*GP*AP*CP*TP*AP*TP*CP*GP*AP*T)-3', afUHEL308 HELICASE
Authors:Buettner, K, Nehring, S, Hopfner, K.P.
Deposit date:2007-03-19
Release date:2007-06-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for DNA duplex separation by a superfamily-2 helicase.
Nat.Struct.Mol.Biol., 14, 2007
2P6U
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BU of 2p6u by Molmil
Apo structure of the Hel308 superfamily 2 helicase
Descriptor: PHOSPHATE ION, afuHEL308 HELICASE
Authors:Buettner, K, Nehring, S, Hopfner, K.P.
Deposit date:2007-03-19
Release date:2007-06-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Structural basis for DNA duplex separation by a superfamily-2 helicase.
Nat.Struct.Mol.Biol., 14, 2007
3P43
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BU of 3p43 by Molmil
Structure and Activities of Archaeal Members of the LigD 3' Phosphoesterase DNA Repair Enzyme Superfamily
Descriptor: CHLORIDE ION, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Smith, P, Nair, P.A, Das, U, Shuman, S.
Deposit date:2010-10-05
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures and activities of archaeal members of the LigD 3'-phosphoesterase DNA repair enzyme superfamily.
Nucleic Acids Res., 39, 2011
3Q8T
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BU of 3q8t by Molmil
Crystal structure of the coiled coil domain of Beclin 1, an essential autophagy protein
Descriptor: Beclin-1
Authors:Li, X, Zhao, Y.
Deposit date:2011-01-07
Release date:2012-01-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG
Nat Commun, 3, 2012
3R0U
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BU of 3r0u by Molmil
Crystal structure of NYSGRC enolase target 200555, a putative dipeptide epimerase from Francisella philomiragia : Tartrate and Mg complex
Descriptor: D(-)-TARTARIC ACID, Enzyme of enolase superfamily, GLYCEROL, ...
Authors:Vetting, M.W, Hillerich, B, Seidel, R.D, Zencheck, W.D, Toro, R, Imker, H.J, Gerlt, J.A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2011-03-09
Release date:2011-04-06
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proc.Natl.Acad.Sci.USA, 109, 2012
6GHD
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BU of 6ghd by Molmil
Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases
Descriptor: 1,2-ETHANEDIOL, Barrier-to-autointegration factor, Emerin, ...
Authors:Samson, C, Petitalot, A, Celli, F, Herrada, I, Ropars, V, Ledu, M.H, Nhiri, N, Arteni, A.A, Buendia, B, ZinnJustin, S.
Deposit date:2018-05-07
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases.
Nucleic Acids Res., 46, 2018
3R0K
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BU of 3r0k by Molmil
Crystal structure of NYSGRC enolase target 200555, a putative dipeptide epimerase from Francisella philomiragia : Tartrate bound, no Mg
Descriptor: D(-)-TARTARIC ACID, Enzyme of enolase superfamily, GLYCEROL, ...
Authors:Vetting, M.W, Hillerich, B, Seidel, R.D, Zencheck, W.D, Toro, R, Imker, H.J, Gerlt, J.A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2011-03-08
Release date:2011-03-30
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proc.Natl.Acad.Sci.USA, 109, 2012
3P4H
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BU of 3p4h by Molmil
Structures of archaeal members of the LigD 3'-phosphoesterase DNA repair enzyme superfamily
Descriptor: ATP-dependent DNA ligase, N-terminal domain protein, DI(HYDROXYETHYL)ETHER, ...
Authors:Smith, P, Nair, P.A, Das, U, Zhu, H, Shuman, S.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structures and activities of archaeal members of the LigD 3'-phosphoesterase DNA repair enzyme superfamily.
Nucleic Acids Res., 39, 2011
3R11
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BU of 3r11 by Molmil
Crystal structure of NYSGRC enolase target 200555, a putative dipeptide epimerase from Francisella philomiragia : Mg and Fumarate complex
Descriptor: Enzyme of enolase superfamily, FUMARIC ACID, GLYCEROL, ...
Authors:Vetting, M.W, Hillerich, B, Seidel, R.D, Zencheck, W.D, Toro, R, Imker, H.J, Gerlt, J.A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2011-03-09
Release date:2011-04-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proc.Natl.Acad.Sci.USA, 109, 2012
3R1Z
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BU of 3r1z by Molmil
Crystal structure of NYSGRC enolase target 200555, a putative dipeptide epimerase from Francisella philomiragia : Complex with L-Ala-L-Glu and L-Ala-D-Glu
Descriptor: ALANINE, D-GLUTAMIC ACID, Enzyme of enolase superfamily, ...
Authors:Vetting, M.W, Hillerich, B, Seidel, R.D, Zencheck, W.D, Toro, R, Imker, H.J, Gerlt, J.A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2011-03-11
Release date:2011-04-20
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proc.Natl.Acad.Sci.USA, 109, 2012
3R10
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BU of 3r10 by Molmil
Crystal structure of NYSGRC enolase target 200555, a putative dipeptide epimerase from Francisella philomiragia : Mg complex
Descriptor: Enzyme of enolase superfamily, GLYCEROL, MAGNESIUM ION, ...
Authors:Vetting, M.W, Hillerich, B, Seidel, R.D, Zencheck, W.D, Toro, R, Imker, H.J, Gerlt, J.A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2011-03-09
Release date:2011-04-20
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proc.Natl.Acad.Sci.USA, 109, 2012
4EN0
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BU of 4en0 by Molmil
Crystal structure of light
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, PHOSPHATE ION, ...
Authors:Zhan, C, Liu, W, Patskovsky, Y, Ramagopal, U.A, Bonanno, J.B, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-04-12
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
Structure, 22, 2014
1NCC
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BU of 1ncc by Molmil
CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, IGG2A-KAPPA NC41 FAB (HEAVY CHAIN), ...
Authors:Tulip, W.R, Varghese, J.N, Colman, P.M.
Deposit date:1992-01-21
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in the interface.
J.Mol.Biol., 227, 1992
4JC3
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BU of 4jc3 by Molmil
14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface
Descriptor: 14-3-3 protein sigma, Estrogen receptor Peptide, MAGNESIUM ION
Authors:Bier, D, Ottmann, C.
Deposit date:2013-02-21
Release date:2013-05-15
Last modified:2017-06-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
1NCB
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BU of 1ncb by Molmil
CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Tulip, W.R, Varghese, J.N, Colman, P.M.
Deposit date:1992-01-21
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in the interface.
J.Mol.Biol., 227, 1992
7AP7
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BU of 7ap7 by Molmil
Structure of the W64R amyloidogenic variant of human lysozyme
Descriptor: Lysozyme C, SULFATE ION
Authors:Vettore, N, Herman, R, Kerff, F, Charlier, P, Sauvage, E, Brans, A, Morray, J, Dobson, C, Kumita, J, Dumoulin, M.
Deposit date:2020-10-16
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Characterisation of the structural, dynamic and aggregation properties of the W64R amyloidogenic variant of human lysozyme.
Biophys.Chem., 271, 2021
1RAL
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BU of 1ral by Molmil
THREE-DIMENSIONAL STRUCTURE OF RAT LIVER 3ALPHA-HYDROXYSTEROID(SLASH)DIHYDRODIOL DEHYDROGENASE: A MEMBER OF THE ALDO-KETO REDUCTASE SUPERFAMILY
Descriptor: 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE
Authors:Hoog, S.S, Pawlowski, J.E, Alzari, P.M, Penning, T.M, Lewis, M.
Deposit date:1994-02-04
Release date:1994-04-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three-dimensional structure of rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase: a member of the aldo-keto reductase superfamily.
Proc.Natl.Acad.Sci.USA, 91, 1994
4JDD
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BU of 4jdd by Molmil
14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface
Descriptor: 14-3-3 protein sigma, Estrogen receptor Peptide, FUSICOCCIN
Authors:Bier, D, Ottmann, C.
Deposit date:2013-02-25
Release date:2013-05-15
Last modified:2017-06-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
5AAN
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BU of 5aan by Molmil
Crystal structure of Drosophila NCS-1 bound to penothiazine FD44
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, CG5907-PA, ...
Authors:Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J.
Deposit date:2015-07-27
Release date:2017-01-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5FYX
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BU of 5fyx by Molmil
Crystal structure of Drosophila NCS-1 bound to penothiazine FD16
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, FREQUENIN 2, ...
Authors:Martinez-Gonzalez, L, Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J.
Deposit date:2016-03-10
Release date:2017-01-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G08
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BU of 5g08 by Molmil
Crystal structure of Drosophila NCS-1 bound to chlorpromazine
Descriptor: 1,2-ETHANEDIOL, 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, CALCIUM ION, ...
Authors:Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J.
Deposit date:2016-03-17
Release date:2017-01-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1JTT
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BU of 1jtt by Molmil
Degenerate interfaces in antigen-antibody complexes
Descriptor: FORMIC ACID, Lysozyme, SODIUM ION, ...
Authors:Decanniere, K, Transue, T.R, Desmyter, A, Maes, D, Muyldermans, S, Wyns, L.
Deposit date:2001-08-22
Release date:2001-12-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Degenerate interfaces in antigen-antibody complexes.
J.Mol.Biol., 313, 2001
4UP5
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BU of 4up5 by Molmil
Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment
Descriptor: 6-methoxy-1,3-benzothiazol-2-amine, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ...
Authors:Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M.
Deposit date:2014-06-12
Release date:2014-11-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
4UP0
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BU of 4up0 by Molmil
Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide
Descriptor: HISTONE H3.1, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ...
Authors:Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M.
Deposit date:2014-06-11
Release date:2014-11-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
1JTO
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BU of 1jto by Molmil
Degenerate interfaces in antigen-antibody complexes
Descriptor: Lysozyme, Vh Single-Domain Antibody
Authors:Decanniere, K, Transue, T.R, Desmyter, A, Maes, D, Muyldermans, S, Wyns, L.
Deposit date:2001-08-21
Release date:2001-10-31
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Degenerate interfaces in antigen-antibody complexes.
J.Mol.Biol., 313, 2001

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