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2XTJ
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The crystal structure of PCSK9 in complex with 1D05 Fab
Descriptor: CALCIUM ION, FAB FROM A HUMAN MONOCLONAL ANTIBODY, 1D05, ...
Authors:Di Marco, S, Volpari, C, Carfi, A.
Deposit date:2010-10-10
Release date:2010-11-03
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Pcsk9-Binding Antibody that Structurally Mimics the Egf(A) Domain of Ldl-Receptor Reduces Ldl Cholesterol in Vivo.
J.Lipid Res., 52, 2011
2WHW
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BU of 2whw by Molmil
Selective oxidation of carbolide C-H bonds by engineered macrolide P450 monooxygenase
Descriptor: CYCLOTRIDECYL 3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSIDE, CYTOCHROME P450 MONOOXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Li, S, Chaulagain, M.R, Knauff, A.R, Podust, L.M, Montgomery, J, Sherman, D.H.
Deposit date:2009-05-07
Release date:2009-10-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Selective Oxidation of Carbolide C-H Bonds by an Engineered Macrolide P450 Mono-Oxygenase.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WHL
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Understanding how diverse mannanases recognise heterogeneous substrates
Descriptor: ACETATE ION, BETA-MANNANASE, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose
Authors:Tailford, L.E, Ducros, V.M.A, Flint, J.E, Roberts, S.M, Morland, C, Zechel, D.L, Smith, N, Bjornvad, M.E, Borchert, T.V, Wilson, K.S, Davies, G.J, Gilbert, H.J.
Deposit date:2009-05-05
Release date:2009-05-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
Biochemistry, 48, 2009
2X1X
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CRYSTAL STRUCTURE OF VEGF-C IN COMPLEX WITH DOMAINS 2 AND 3 OF VEGFR2 IN A TETRAGONAL CRYSTAL FORM
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MERCURY (II) ION, ...
Authors:Leppanen, V.-M, Prota, A.E, Jeltsch, M, Anisimov, A, Kalkkinen, N, Strandin, T, Lankinen, H, Goldman, A, Ballmer-Hofer, K, Alitalo, K.
Deposit date:2010-01-08
Release date:2010-02-09
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Determinants of Growth Factor Binding and Specificity by Vegf Receptor 2.
Proc.Natl.Acad.Sci.USA, 107, 2010
2HIH
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BU of 2hih by Molmil
Crystal structure of Staphylococcus hyicus lipase
Descriptor: CALCIUM ION, Lipase 46 kDa form, ZINC ION
Authors:Tiesinga, J.J.W, van Pouderoyen, G, Nardini, M, Dijkstra, B.W.
Deposit date:2006-06-29
Release date:2007-05-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural basis of phospholipase activity of Staphylococcus hyicus lipase.
J.Mol.Biol., 371, 2007
2XB3
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BU of 2xb3 by Molmil
The Structure of Cyanobacterial PsbP
Descriptor: PSBP PROTEIN, ZINC ION
Authors:Michoux, F, Takasaka, K, Nixon, P, Murray, J.W.
Deposit date:2010-04-03
Release date:2010-08-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of Cyanop at 2.8A: Implications for the Evolution and Function of the Psbp Subunit of Photosystem II.
Biochemistry, 49, 2010
2HRZ
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BU of 2hrz by Molmil
The crystal structure of the nucleoside-diphosphate-sugar epimerase from Agrobacterium tumefaciens
Descriptor: Nucleoside-diphosphate-sugar epimerase
Authors:Zhang, R, Xu, X, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-07-20
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The crystal structure of the nucleoside-diphosphate-sugar epimerase from Agrobacterium tumefaciens
To be Published
2WJM
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BU of 2wjm by Molmil
Lipidic sponge phase crystal structure of the photosynthetic reaction centre from Blastochloris viridis (low dose)
Descriptor: 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ...
Authors:Woehri, A.B, Wahlgren, W.Y, Malmerberg, E, Johansson, L.C, Neutze, R, Katona, G.
Deposit date:2009-05-27
Release date:2009-09-22
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Lipidic sponge phase crystal structure of a photosynthetic reaction center reveals lipids on the protein surface.
Biochemistry, 48, 2009
2HLR
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BU of 2hlr by Molmil
Crystal Structure of the Extracellular Domain of the Type II BMP Receptor
Descriptor: Bone morphogenetic protein receptor type-2
Authors:Mace, P.D, Cutfield, J.F, Cutfield, S.M.
Deposit date:2006-07-10
Release date:2006-11-28
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:High resolution structures of the bone morphogenetic protein type II receptor in two crystal forms: Implications for ligand binding
Biochem.Biophys.Res.Commun., 351, 2006
2X0O
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BU of 2x0o by Molmil
Apo structure of the Alcaligin biosynthesis protein C (AlcC) from Bordetella bronchiseptica
Descriptor: ALCALIGIN BIOSYNTHESIS PROTEIN, SULFATE ION
Authors:Johnson, K.A, Schmelz, S, Kadi, N, Mcmahon, S.A, Oke, M, Liu, H, Carter, L.G, White, M.F, Challis, G.L, Naismith, J.H.
Deposit date:2009-12-16
Release date:2010-07-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
2XB4
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BU of 2xb4 by Molmil
Crystal structures of zinc containing Adenylate kinase from Desulfovibrio gigas
Descriptor: ADENYLATE KINASE, S,R MESO-TARTARIC ACID, ZINC ION
Authors:Mukhopadhyay, A, Kladova, A.V, Gavel, O.Y, Calvete, J.J, Shnyrov, V.L, Moura, I, Moura, J.J.G, Bursakov, S.A, Romao, M.J, Trincao, J.
Deposit date:2010-04-05
Release date:2010-09-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Zinc-, Cobalt-, and Iron-Containing Adenylate Kinase from Desulfovibrio Gigas: A Novel Metal-Containing Adenylate Kinase from Gram-Negative Bacteria.
J.Biol.Inorg.Chem., 16, 2011
2HTA
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BU of 2hta by Molmil
Crystal Structure of a putative mutarotase (YeaD) from Salmonella typhimurium in orthorhombic form
Descriptor: GLYCEROL, Putative enzyme related to aldose 1-epimerase, SULFATE ION
Authors:Chittori, S, Simanshu, D.K, Savithri, H.S, Murthy, M.R.N.
Deposit date:2006-07-25
Release date:2007-01-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the putative mutarotase YeaD from Salmonella typhimurium: structural comparison with galactose mutarotases.
Acta Crystallogr.,Sect.D, 63, 2007
2X8Q
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BU of 2x8q by Molmil
Cryo-EM 3D model of the icosahedral particle composed of Rous sarcoma virus capsid protein pentamers
Descriptor: CAPSID PROTEIN P27
Authors:K Hyun, J, Radjainia, M, Kingston, R.L, Mitra, A.K.
Deposit date:2010-03-11
Release date:2010-05-19
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (18.299999 Å)
Cite:Proton-Driven Assembly of the Rous Sarcoma Virus Capsid Protein Results in the Formation of Icosahedral Particles.
J.Biol.Chem., 285, 2010
2HNL
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BU of 2hnl by Molmil
Structure of the prostaglandin D synthase from the parasitic nematode Onchocerca volvulus
Descriptor: GLUTATHIONE, Glutathione S-transferase 1
Authors:Perbandt, M, Hoppner, J, Betzel, C, Liebau, E.
Deposit date:2006-07-13
Release date:2007-07-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the extracellular glutathione S-transferase OvGST1 from the human pathogenic parasite Onchocerca volvulus.
J.Mol.Biol., 377, 2008
2WJ4
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BU of 2wj4 by Molmil
CRYSTAL STRUCTURE OF THE COFACTOR-DEVOID 1-H-3-HYDROXY-4- OXOQUINALDINE 2,4-DIOXYGENASE (HOD) FROM ARTHROBACTER NITROGUAJACOLICUS RU61A ANAEROBICALLY COMPLEXED WITH ITS NATURAL SUBSTRATE 1-H-3-HYDROXY-4-OXOQUINALDINE
Descriptor: 1H-3-HYDROXY-4-OXOQUINALDINE 2,4-DIOXYGENASE, 3-HYDROXY-2-METHYLQUINOLIN-4(1H)-ONE, GLYCEROL, ...
Authors:Steiner, R.A.
Deposit date:2009-05-20
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Cofactor-Independent Dioxygenation of N-Heteroaromatic Compounds at the {Alpha}/{Beta}-Hydrolase Fold.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WH8
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BU of 2wh8 by Molmil
Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines
Descriptor: 5-AMINO-2-{4-[(4-AMINOPHENYL)SULFANYL]PHENYL}-1H-ISOINDOLE-1,3(2H)-DIONE, PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 130
Authors:Podust, L.M, Ouellet, H, von Kries, J.P, Ortiz de Montellano, P.R.
Deposit date:2009-05-01
Release date:2009-07-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines.
J. Biol. Chem., 284, 2009
2HVJ
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BU of 2hvj by Molmil
Crystal structure of KcsA-Fab-TBA complex in low K+
Descriptor: (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, NONAN-1-OL, POTASSIUM ION, ...
Authors:Zhou, Y.
Deposit date:2006-07-28
Release date:2007-02-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel.
J.Mol.Biol., 366, 2007
2HVK
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BU of 2hvk by Molmil
crystal structure of the KcsA-Fab-TBA complex in high K+
Descriptor: (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, Antibody Fab heavy chain, Antibody Fab light chain, ...
Authors:Zhou, Y.
Deposit date:2006-07-28
Release date:2007-02-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel.
J.Mol.Biol., 366, 2007
2ZQP
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BU of 2zqp by Molmil
Crystal Structure of SecYE translocon from Thermus thermophilus
Descriptor: Preprotein translocase SecE subunit, Preprotein translocase SecY subunit
Authors:Tsukazaki, T, Nureki, O.
Deposit date:2008-08-14
Release date:2008-10-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (6 Å)
Cite:Conformational transition of Sec machinery inferred from bacterial SecYE structures
Nature, 455, 2008
2ZR6
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BU of 2zr6 by Molmil
Crystal structure of a mutant PIN1 peptidyl-prolyl cis-trans isomerase
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION
Authors:Jobichen, C, Yih-Cherng, L, Sivaraman, J.
Deposit date:2008-08-22
Release date:2009-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural studies on PIN1 mutants
To be Published
2HV7
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BU of 2hv7 by Molmil
Crystal structure of phosphotyrosyl phosphatase activator bound to ATPgammaS
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Protein phosphatase 2A, regulatory subunit B
Authors:Chao, Y, Jeffrey, J.D, Shi, Y.
Deposit date:2006-07-27
Release date:2006-08-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and mechanism of the phosphotyrosyl phosphatase activator.
Mol.Cell, 23, 2006
2HSY
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BU of 2hsy by Molmil
Solution structure of Thioredoxin 2 from Saccharomyces cerevisiae
Descriptor: Thioredoxin II
Authors:Amorim, G.C, Valente, A.P, Almeida, F.C.L.
Deposit date:2006-07-24
Release date:2007-03-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR solution structure of the reduced form of thioredoxin 2 from Saccharomyces cerevisiae
J.Biomol.Nmr, 38, 2007
2HVX
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BU of 2hvx by Molmil
Discovery of Potent, Orally Active, Nonpeptide Inhibitors of Human Mast Cell Chymase by Using Structure-Based Drug Design
Descriptor: Chymase, [(1S)-1-(5-CHLORO-1-BENZOTHIEN-3-YL)-2-(2-NAPHTHYLAMINO)-2-OXOETHYL]PHOSPHONIC ACID
Authors:Greco, M.N, Hawkins, M.J, Powell, E.T, Almond, H.R, de Garavilla, L, Wang, Y, Minor, L.A, Wells, G.I, Di Cera, E, Cantwell, A.M, Savvides, S.N, Damiano, B.P, Maryanoff, B.E.
Deposit date:2006-07-31
Release date:2007-06-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase.
J.Med.Chem., 50, 2007
2HTT
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BU of 2htt by Molmil
Ruthenium Hexammine ion interactions with Z-DNA
Descriptor: DNA (5'-D(*DCP*DGP*DCP*DGP*DCP*DA)-3'), DNA (5'-D(*DTP*DGP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(P*DTP*DG)-3'), ...
Authors:Bharanidharan, D, Thiyagarajan, S, Gautham, N.
Deposit date:2006-07-26
Release date:2006-08-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Hexammineruthenium(III) ion interactions with Z-DNA
Acta Crystallogr.,Sect.F, 63, 2007
2ZTL
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BU of 2ztl by Molmil
Closed conformation of D-3-hydroxybutyrate dehydrogenase complexed with NAD+ and L-3-hydroxybutyrate
Descriptor: (3S)-3-HYDROXYBUTANOIC ACID, D(-)-3-hydroxybutyrate dehydrogenase, GLYCEROL, ...
Authors:Nakashima, K, Nakajima, Y, Ito, K, Yoshimoto, T.
Deposit date:2008-10-07
Release date:2009-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor.
J.Biochem., 145, 2009

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