2ZTL

Closed conformation of D-3-hydroxybutyrate dehydrogenase complexed with NAD+ and L-3-hydroxybutyrate

Summary for 2ZTL

Entry DOI	10.2210/pdb2ztl/pdb
Related	1WMB 1X1T 2ZTM
Descriptor	D(-)-3-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (3S)-3-HYDROXYBUTANOIC ACID, ... (6 entities in total)
Functional Keywords	short chain dehydrogenase/reductase, sdr family, nad, nadh, hbdh, oxidoreductase
Biological source	Pseudomonas fragi
Total number of polymer chains	4
Total formula weight	110060.48
Authors	Nakashima, K.,Nakajima, Y.,Ito, K.,Yoshimoto, T. (deposition date: 2008-10-07, release date: 2009-08-25, Last modification date: 2023-11-01)
Primary citation	Nakashima, K.,Ito, K.,Nakajima, Y.,Yamazawa, R.,Miyakawa, S.,Yoshimoto, T. Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor. J.Biochem., 145:467-479, 2009 Cited by PubMed: 19122202 DOI: 10.1093/jb/mvn186 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation