9CQI
 
 | |
9CQF
 | |
9CQG
 | |
9BCJ
 | | Crystal structure of human hemoglobin in complex with the HbpA receptor from Corynebacterium diphtheriae | | Descriptor: | GLYCEROL, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | | Authors: | Mahoney, B.J, Cascio, D, Clubb, R.T. | | Deposit date: | 2024-04-09 | | Release date: | 2025-01-08 | | Method: | X-RAY DIFFRACTION (1.691 Å) | | Cite: | Molecular basis of hemoglobin binding and heme removal in Corynebacterium diphtheriae.
Proc.Natl.Acad.Sci.USA, 122, 2025
|
|
9EV3
 | | Corynebacterium glutamicum pyruvate:quinone oxidoreductase (PQO) purified from bacteria grown in acetate minimal medium | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ... | | Authors: | Da Silva Lameira, C, Muenssinger, S, Yang, L, Eikmanns, B.J, Bellinzoni, M. | | Deposit date: | 2024-03-28 | | Release date: | 2024-08-07 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.219 Å) | | Cite: | Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features.
Febs J., 291, 2024
|
|
9EV5
 | | Corynebacterium glutamicum CS176 pyruvate:quinone oxidoreductase (PQO) in complex with FAD and thiamine diphosphate-magnesium ion | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ... | | Authors: | Da Silva Lameira, C, Muenssinger, S, Yang, L, Eikmanns, B.J, Bellinzoni, M. | | Deposit date: | 2024-03-28 | | Release date: | 2024-08-07 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.863 Å) | | Cite: | Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features.
Febs J., 291, 2024
|
|
9EV4
 | | Pyruvate:quinone oxidoreductase (PQO) from Corynebacterium glutamicum CS176 | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (Cytochrome), ... | | Authors: | Da Silva Lameira, C, Muenssinger, S, Yang, L, Eikmanns, B.J, Bellinzoni, M. | | Deposit date: | 2024-03-28 | | Release date: | 2024-08-07 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.474 Å) | | Cite: | Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features.
Febs J., 291, 2024
|
|
9EV6
 | | Corynebacterium glutamicum pyruvate:quinone oxidoreductase (PQO), C-terminal truncated construct | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ... | | Authors: | Da Silva Lameira, C, Muenssinger, S, Yang, L, Eikmanns, B.J, Bellinzoni, M. | | Deposit date: | 2024-03-28 | | Release date: | 2024-08-07 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.891 Å) | | Cite: | Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features.
Febs J., 291, 2024
|
|
6T9J
 | | SAGA Tra1 module | | Descriptor: | Transcription factor SPT20, Transcription initiation factor TFIID subunit 12, Transcription-associated protein 1 | | Authors: | Wang, H, Cheung, A, Cramer, P. | | Deposit date: | 2019-10-28 | | Release date: | 2020-01-29 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of the transcription coactivator SAGA.
Nature, 577, 2020
|
|
4U43
 | | MAP4K4 in complex with inhibitor (compound 6) | | Descriptor: | Mitogen-activated protein kinase kinase kinase kinase 4, N-(pyridin-3-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine | | Authors: | Harris, S.F, Wu, P, Coons, M. | | Deposit date: | 2014-07-23 | | Release date: | 2014-09-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors.
Bioorg.Med.Chem.Lett., 24, 2014
|
|
6TF9
 | | Structure of the vertebrate gamma-Tubulin Ring Complex | | Descriptor: | Actin, cytoplasmic 1, Belt helices 1,2,3,4, ... | | Authors: | Zupa, E, Pfeffer, S. | | Deposit date: | 2019-11-13 | | Release date: | 2019-12-11 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Insights into the assembly and activation of the microtubule nucleator gamma-TuRC.
Nature, 578, 2020
|
|
4U82
 | | Structure of S. aureus undecaprenyl diphosphate synthase in complex with FSPP and sulfate | | Descriptor: | Isoprenyl transferase, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ... | | Authors: | Zhu, W, Oldfield, E. | | Deposit date: | 2014-07-31 | | Release date: | 2015-02-04 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Antibacterial drug leads: DNA and enzyme multitargeting.
J.Med.Chem., 58, 2015
|
|
6T8A
 | | Thrombin in complex with diphenyl ((4-carbamimidoylphenyl)((S)-1-((R)-3-cyclohexyl 2-((phenylmethyl)sulfonamido)propanoyl)pyrrolidine-2-carboxamido)methyl)phosphonate (MI-492) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, Hirudin variant-2, ... | | Authors: | Ngaha, S.A, Sandner, A, Huber, S, Heine, A, Steinmetzer, T, Pilgram, O. | | Deposit date: | 2019-10-24 | | Release date: | 2020-11-18 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Thrombin in complex with diphenyl ((4-carbamimidoylphenyl)((S)-1-((R)-3-cyclohexyl-2-((phenylmethyl)sulfonamido)propanoyl)pyrrolidine-2-carboxamido)methyl)phosphonate (MI-492)
to be published
|
|
6T2V
 | | Cryo-EM structure of the RecBCD in complex with Chi-plus2 substrate | | Descriptor: | DNA (Chi-plus2), RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ... | | Authors: | Cheng, K, Wilkinson, M, Wigley, D.B. | | Deposit date: | 2019-10-09 | | Release date: | 2020-01-01 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
|
|
6TA5
 | | OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in nanodiscs | | Descriptor: | Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM | | Authors: | Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. | | Deposit date: | 2019-10-29 | | Release date: | 2020-09-16 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex.
Nat Commun, 11, 2020
|
|
6TRE
 | | Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 32-fold symmetry applied | | Descriptor: | Flagellar M-ring protein | | Authors: | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | | Deposit date: | 2019-12-18 | | Release date: | 2020-03-18 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of the bacterial flagellar rotor MS-ring: a minimum inventory/maximum diversity system.
To Be Published
|
|
6TU4
 | | Structure of Plasmodium Actin1 filament | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-1, Jasplakinolide, ... | | Authors: | Vahokoski, J, Calder, L.J, Lopez, A.J, Rosenthal, P.B, Kursula, I. | | Deposit date: | 2020-01-02 | | Release date: | 2021-01-13 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | High-resolution structures of malaria parasite actomyosin and actin filaments.
Plos Pathog., 18, 2022
|
|
6TIK
 | | Hepatitis B virus core shell--virus-like particle with NadA epitope | | Descriptor: | Capsid protein,Putative adhesin/invasin,Capsid protein,Factor H-binding protein | | Authors: | Roseman, A.M, Colllins, R.F, Derrick, J.P. | | Deposit date: | 2019-11-22 | | Release date: | 2020-04-29 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | An assessment of the use of Hepatitis B Virus core protein virus-like particles to display heterologous antigens from Neisseria meningitidis.
Vaccine, 38, 2020
|
|
6TU7
 | | Structure of PfMyoA decorated Plasmodium Act1 filament | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-1, Jasplakinolide, ... | | Authors: | Vahokoski, J, Calder, L.J, Lopez, A.J, Rosenthal, P.B, Kursula, I. | | Deposit date: | 2020-01-03 | | Release date: | 2021-01-13 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | High-resolution structures of malaria parasite actomyosin and actin filaments.
Plos Pathog., 18, 2022
|
|
6TUC
 | | Human Aldose Reductase in complex with ALR25 | | Descriptor: | 2-(2-((3-boronobenzyl)carbamoyl)-5-fluorophenoxy)acetic acid, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Sandner, A, Heine, A, Klebe, G. | | Deposit date: | 2020-01-06 | | Release date: | 2021-01-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.06 Å) | | Cite: | Human Aldose Reductase in complex with SAR25
To Be Published
|
|
6TUF
 | | Human Aldose Reductase in complex with ALR43 | | Descriptor: | 2-[5-fluoranyl-2-[[3-[methyl(oxidanyl)-$l^{3}-sulfanyl]phenyl]methylcarbamoyl]phenoxy]ethanoic acid, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Sandner, A, Heine, A, Klebe, G. | | Deposit date: | 2020-01-07 | | Release date: | 2021-01-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Human Aldose Reductase in complex with SAR25
To Be Published
|
|
7KIU
 | |
6Y02
 | | Thrombin in complex with 13k | | Descriptor: | (2~{S})-1-[(2~{R})-2-azanyl-3-phenyl-propanoyl]-~{N}-[(5-bromanylfuran-2-yl)methyl]pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | | Authors: | Sandner, A, Heine, A, Klebe, G, Abazi, N. | | Deposit date: | 2020-02-06 | | Release date: | 2021-02-17 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Thrombin in complex with 13k
To be published
|
|
8AOW
 | | CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with m7GTP and SAH ligands | | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Jones, R, Hons, M, Reguera, J. | | Deposit date: | 2022-08-08 | | Release date: | 2023-03-29 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
4U3S
 | | Crystal structure of Coh3ScaB-XDoc_M1ScaA complex: A N-terminal interface mutant of type II Cohesin-X-Dockerin complex from Acetivibrio cellulolyticus | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, Cellulosomal scaffoldin, ... | | Authors: | Alves, V.D, Cameron, K, Najmudin, S.H, Fontes, C.M.G.A. | | Deposit date: | 2014-07-22 | | Release date: | 2015-07-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Crystal structure of Coh3ScaB-XDoc_M1ScaA complex: A N-terminal interface mutant of type II Cohesin-X-Dockerin complex from Acetivibrio cellulolyticus
To Be Published
|
|
