9JKB
 
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5D1O
 
 | Archaeal ATP-dependent RNA ligase - form 1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA ligase, MAGNESIUM ION, ... | Authors: | Murakami, K.S. | Deposit date: | 2015-08-04 | Release date: | 2016-03-09 | Last modified: | 2025-04-02 | Method: | X-RAY DIFFRACTION (2.648 Å) | Cite: | Structural and mutational analysis of archaeal ATP-dependent RNA ligase identifies amino acids required for RNA binding and catalysis. Nucleic Acids Res., 44, 2016
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4CHI
 
 | (R)-selective amine transaminase from Aspergillus fumigatus at 1.27 A resolution | Descriptor: | BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE, CHLORIDE ION, GLYCEROL, ... | Authors: | Thomsen, M, Palm, G.J, Hinrichs, W. | Deposit date: | 2013-12-02 | Release date: | 2014-04-30 | Last modified: | 2025-04-09 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Crystallographic Characterization of the (R)-Selective Amine Transaminase from Aspergillus Fumigatus. Acta Crystallogr.,Sect.D, 70, 2014
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7OFV
 
 | NMR-guided design of potent and selective EphA4 agonistic ligands | Descriptor: | ACETATE ION, EphA4 agonist ligand, Ephrin type-A receptor 4 | Authors: | Ganichkin, O.M, Craig, T.K, Baggio, C, Pellecchia, M. | Deposit date: | 2021-05-05 | Release date: | 2021-08-11 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | NMR-Guided Design of Potent and Selective EphA4 Agonistic Ligands. J.Med.Chem., 64, 2021
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6OXI
 
 | Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (UAA) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M. | Deposit date: | 2019-05-13 | Release date: | 2019-08-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.495 Å) | Cite: | Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Res., 47, 2019
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6OTR
 
 | Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (AAU) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Pavelich, I.P, Hoffer, E.D, Maehigashi, T, Dunham, C.M. | Deposit date: | 2019-05-03 | Release date: | 2019-08-21 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Res., 47, 2019
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6OXA
 
 | Dimeric E.coli YoeB bound to Thermus thermophilus 70S pre-cleavage (AAU) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M. | Deposit date: | 2019-05-13 | Release date: | 2019-08-21 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Res., 47, 2019
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2Q8O
 
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1T5D
 
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9EWA
 
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4US8
 
 | Aldehyde Oxidoreductase from Desulfovibrio gigas (MOP), soaked with benzaldehyde | Descriptor: | (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), ALDEHYDE OXIDOREDUCTASE, BICARBONATE ION, ... | Authors: | Correia, H.D, Romao, M.J, Santos-Silva, T. | Deposit date: | 2014-07-03 | Release date: | 2014-10-08 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Aromatic Aldehydes at the Active Site of Aldehyde Oxidoreductase from Desulfovibrio Gigas: Reactivity and Molecular Details of the Enzyme-Substrate and Enzyme-Product Interaction. J.Biol.Inorg.Chem., 20, 2015
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4LNB
 
 | Aspergillus fumigatus protein farnesyltransferase ternary complex with farnesyldiphosphate and ethylenediamine scaffold inhibitor 5 | Descriptor: | 1,2-ETHANEDIOL, CaaX farnesyltransferase alpha subunit Ram2, CaaX farnesyltransferase beta subunit Ram1, ... | Authors: | Mabanglo, M.F, Hast, M.A, Beese, L.S. | Deposit date: | 2013-07-11 | Release date: | 2014-01-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.752 Å) | Cite: | Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design. Protein Sci., 23, 2014
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9EWL
 
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8DCD
 
 | RNA ligase RtcB from Pyrococcus horikoshii in complex with Zn2+ and GTP | Descriptor: | CHLORIDE ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2022-06-16 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structures of RNA ligase RtcB in complexes with divalent cations and GTP. Rna, 28, 2022
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8DC9
 
 | RNA ligase RtcB from Pyrococcus horikoshii in complex with Mn2+ and GTP | Descriptor: | CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2022-06-16 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structures of RNA ligase RtcB in complexes with divalent cations and GTP. Rna, 28, 2022
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8DCB
 
 | RNA ligase RtcB from Pyrococcus horikoshii in complex with Ni2+ and GTP | Descriptor: | CHLORIDE ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2022-06-16 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of RNA ligase RtcB in complexes with divalent cations and GTP. Rna, 28, 2022
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8DCG
 
 | Structure of guanylylated RNA ligase RtcB from Pyrococcus horikoshii | Descriptor: | CHLORIDE ION, GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2022-06-16 | Release date: | 2022-10-12 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structures of RNA ligase RtcB in complexes with divalent cations and GTP. Rna, 28, 2022
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8DCF
 
 | RNA ligase RtcB from Pyrococcus horikoshii in complex with Cu2+ and GTP | Descriptor: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2022-06-16 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structures of RNA ligase RtcB in complexes with divalent cations and GTP. Rna, 28, 2022
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8DCA
 
 | RNA ligase RtcB from Pyrococcus horikoshii in complex with Co2+ and GTP | Descriptor: | COBALT (II) ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2022-06-16 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structures of RNA ligase RtcB in complexes with divalent cations and GTP. Rna, 28, 2022
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7U9K
 
 | Staphylococcus aureus D-alanine-D-alanine ligase in complex with ATP, D-ala-D-ala, Mg2+ and K+ | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, D-alanine--D-alanine ligase, ... | Authors: | Pederick, J.L, Bruning, J.B. | Deposit date: | 2022-03-10 | Release date: | 2023-03-15 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-guided design and synthesis of ATP-competitive N-acyl-substituted sulfamide d-alanine-d-alanine ligase inhibitors. Bioorg.Med.Chem., 96, 2023
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3FJP
 
 | Apo structure of Biotin protein ligase from Aquifex aeolicus | Descriptor: | Biotin [acetyl-CoA-carboxylase] ligase, SULFATE ION | Authors: | McNae, I.W, Tron, C.M, Baxter, R.L, Walkinshaw, M.D, Campopiano, D.J. | Deposit date: | 2008-12-15 | Release date: | 2009-06-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity. J.Mol.Biol., 387, 2009
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2RCJ
 
 | Solution structure of human Immunoglobulin M | Descriptor: | IgA1 heavy chain, IgA1 light chain, J chain | Authors: | Perkins, S.J, Nealis, A.S, Sutton, B.J, Feinstein, A. | Deposit date: | 2007-09-20 | Release date: | 2008-01-22 | Last modified: | 2024-02-21 | Method: | SOLUTION SCATTERING | Cite: | Solution structure of human and mouse immunoglobulin M by synchrotron X-ray scattering and molecular graphics modelling. A possible mechanism for complement activation. J.Mol.Biol., 221, 1991
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1WNL
 
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1WQW
 
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4XM6
 
 | Anthrax toxin lethal factor with ligand-induced binding pocket | Descriptor: | 1,2-ETHANEDIOL, Lethal factor, N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-N~2~-(2-methylpropyl)-D-valinamide, ... | Authors: | Maize, K.M, De la Mora-Rey, T, Finzel, B.C. | Deposit date: | 2015-01-14 | Release date: | 2015-11-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.352 Å) | Cite: | Ligand-induced expansion of the S1' site in the anthrax toxin lethal factor. Febs Lett., 589, 2015
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