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9JKB
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BU of 9jkb by Molmil
Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO4 SCF ubiquition ligase complex
Descriptor: Cullin-1, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
Authors:Zhu, W, Xu, C.
Deposit date:2024-09-15
Release date:2024-10-23
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Structure of the CUL1-RBX1-SKP1-FBXO4 SCF ubiquitin ligase complex.
Biochem.Biophys.Res.Commun., 735, 2024
5D1O
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BU of 5d1o by Molmil
Archaeal ATP-dependent RNA ligase - form 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA ligase, MAGNESIUM ION, ...
Authors:Murakami, K.S.
Deposit date:2015-08-04
Release date:2016-03-09
Last modified:2025-04-02
Method:X-RAY DIFFRACTION (2.648 Å)
Cite:Structural and mutational analysis of archaeal ATP-dependent RNA ligase identifies amino acids required for RNA binding and catalysis.
Nucleic Acids Res., 44, 2016
4CHI
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BU of 4chi by Molmil
(R)-selective amine transaminase from Aspergillus fumigatus at 1.27 A resolution
Descriptor: BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE, CHLORIDE ION, GLYCEROL, ...
Authors:Thomsen, M, Palm, G.J, Hinrichs, W.
Deposit date:2013-12-02
Release date:2014-04-30
Last modified:2025-04-09
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Crystallographic Characterization of the (R)-Selective Amine Transaminase from Aspergillus Fumigatus.
Acta Crystallogr.,Sect.D, 70, 2014
7OFV
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BU of 7ofv by Molmil
NMR-guided design of potent and selective EphA4 agonistic ligands
Descriptor: ACETATE ION, EphA4 agonist ligand, Ephrin type-A receptor 4
Authors:Ganichkin, O.M, Craig, T.K, Baggio, C, Pellecchia, M.
Deposit date:2021-05-05
Release date:2021-08-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:NMR-Guided Design of Potent and Selective EphA4 Agonistic Ligands.
J.Med.Chem., 64, 2021
6OXI
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BU of 6oxi by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (UAA)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.495 Å)
Cite:Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
6OTR
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BU of 6otr by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (AAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Pavelich, I.P, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
Deposit date:2019-05-03
Release date:2019-08-21
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
6OXA
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BU of 6oxa by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S pre-cleavage (AAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
2Q8O
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BU of 2q8o by Molmil
crystal structure of mouse GITR ligand dimer
Descriptor: GITR ligand
Authors:Zhaocai, Z, Yukiko, T.
Deposit date:2007-06-11
Release date:2007-12-25
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for ligand-mediated mouse GITR activation.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1T5D
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BU of 1t5d by Molmil
4-Chlorobenzoyl-CoA Ligase/Synthetase bound to 4-chlorobenzoate
Descriptor: 4-CHLORO-BENZOIC ACID, 4-chlorobenzoyl CoA ligase, CALCIUM ION
Authors:Gulick, A.M, Lu, X, Dunaway-Mariano, D.
Deposit date:2004-05-04
Release date:2004-08-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Crystal Structure of 4-Chlorobenzoate:CoA Ligase/Synthetase in the Unliganded and Aryl Substrate-Bound States
Biochemistry, 43, 2004
9EWA
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BU of 9ewa by Molmil
The sTeLIC pentameric Ligand-Gated Ion Channel (wild-type) in complex with 4-Bromophenethylamine
Descriptor: 2-(4-bromophenyl)ethanamine, Cys-loop ligand-gated ion channel, nonyl beta-D-glucopyranoside
Authors:Fourati, Z, Delarue, M.
Deposit date:2024-04-03
Release date:2025-03-26
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (3.006 Å)
Cite:Vestibular modulation by stimulant derivatives in a pentameric ligand-gated ion channel.
Br.J.Pharmacol., 182, 2025
4US8
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BU of 4us8 by Molmil
Aldehyde Oxidoreductase from Desulfovibrio gigas (MOP), soaked with benzaldehyde
Descriptor: (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), ALDEHYDE OXIDOREDUCTASE, BICARBONATE ION, ...
Authors:Correia, H.D, Romao, M.J, Santos-Silva, T.
Deposit date:2014-07-03
Release date:2014-10-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Aromatic Aldehydes at the Active Site of Aldehyde Oxidoreductase from Desulfovibrio Gigas: Reactivity and Molecular Details of the Enzyme-Substrate and Enzyme-Product Interaction.
J.Biol.Inorg.Chem., 20, 2015
4LNB
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BU of 4lnb by Molmil
Aspergillus fumigatus protein farnesyltransferase ternary complex with farnesyldiphosphate and ethylenediamine scaffold inhibitor 5
Descriptor: 1,2-ETHANEDIOL, CaaX farnesyltransferase alpha subunit Ram2, CaaX farnesyltransferase beta subunit Ram1, ...
Authors:Mabanglo, M.F, Hast, M.A, Beese, L.S.
Deposit date:2013-07-11
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design.
Protein Sci., 23, 2014
9EWL
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BU of 9ewl by Molmil
The sTeLIC pentameric Ligand-Gated Ion Channel (wild-type) in complex with 4-bromoamphetamine
Descriptor: (2S)-1-(4-bromophenyl)propan-2-amine, Cys-loop ligand-gated ion channel, nonyl beta-D-glucopyranoside
Authors:Fourati, Z, Delarue, M.
Deposit date:2024-04-04
Release date:2025-03-26
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Vestibular modulation by stimulant derivatives in a pentameric ligand-gated ion channel.
Br.J.Pharmacol., 182, 2025
8DCD
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BU of 8dcd by Molmil
RNA ligase RtcB from Pyrococcus horikoshii in complex with Zn2+ and GTP
Descriptor: CHLORIDE ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Jacewicz, A, Dantuluri, S, Shuman, S.
Deposit date:2022-06-16
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structures of RNA ligase RtcB in complexes with divalent cations and GTP.
Rna, 28, 2022
8DC9
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BU of 8dc9 by Molmil
RNA ligase RtcB from Pyrococcus horikoshii in complex with Mn2+ and GTP
Descriptor: CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Jacewicz, A, Dantuluri, S, Shuman, S.
Deposit date:2022-06-16
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structures of RNA ligase RtcB in complexes with divalent cations and GTP.
Rna, 28, 2022
8DCB
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BU of 8dcb by Molmil
RNA ligase RtcB from Pyrococcus horikoshii in complex with Ni2+ and GTP
Descriptor: CHLORIDE ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Jacewicz, A, Dantuluri, S, Shuman, S.
Deposit date:2022-06-16
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of RNA ligase RtcB in complexes with divalent cations and GTP.
Rna, 28, 2022
8DCG
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BU of 8dcg by Molmil
Structure of guanylylated RNA ligase RtcB from Pyrococcus horikoshii
Descriptor: CHLORIDE ION, GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION, ...
Authors:Jacewicz, A, Dantuluri, S, Shuman, S.
Deposit date:2022-06-16
Release date:2022-10-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structures of RNA ligase RtcB in complexes with divalent cations and GTP.
Rna, 28, 2022
8DCF
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BU of 8dcf by Molmil
RNA ligase RtcB from Pyrococcus horikoshii in complex with Cu2+ and GTP
Descriptor: CHLORIDE ION, COPPER (II) ION, GLYCEROL, ...
Authors:Jacewicz, A, Dantuluri, S, Shuman, S.
Deposit date:2022-06-16
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structures of RNA ligase RtcB in complexes with divalent cations and GTP.
Rna, 28, 2022
8DCA
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BU of 8dca by Molmil
RNA ligase RtcB from Pyrococcus horikoshii in complex with Co2+ and GTP
Descriptor: COBALT (II) ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Jacewicz, A, Dantuluri, S, Shuman, S.
Deposit date:2022-06-16
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structures of RNA ligase RtcB in complexes with divalent cations and GTP.
Rna, 28, 2022
7U9K
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BU of 7u9k by Molmil
Staphylococcus aureus D-alanine-D-alanine ligase in complex with ATP, D-ala-D-ala, Mg2+ and K+
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, D-alanine--D-alanine ligase, ...
Authors:Pederick, J.L, Bruning, J.B.
Deposit date:2022-03-10
Release date:2023-03-15
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-guided design and synthesis of ATP-competitive N-acyl-substituted sulfamide d-alanine-d-alanine ligase inhibitors.
Bioorg.Med.Chem., 96, 2023
3FJP
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BU of 3fjp by Molmil
Apo structure of Biotin protein ligase from Aquifex aeolicus
Descriptor: Biotin [acetyl-CoA-carboxylase] ligase, SULFATE ION
Authors:McNae, I.W, Tron, C.M, Baxter, R.L, Walkinshaw, M.D, Campopiano, D.J.
Deposit date:2008-12-15
Release date:2009-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity.
J.Mol.Biol., 387, 2009
2RCJ
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BU of 2rcj by Molmil
Solution structure of human Immunoglobulin M
Descriptor: IgA1 heavy chain, IgA1 light chain, J chain
Authors:Perkins, S.J, Nealis, A.S, Sutton, B.J, Feinstein, A.
Deposit date:2007-09-20
Release date:2008-01-22
Last modified:2024-02-21
Method:SOLUTION SCATTERING
Cite:Solution structure of human and mouse immunoglobulin M by synchrotron X-ray scattering and molecular graphics modelling. A possible mechanism for complement activation.
J.Mol.Biol., 221, 1991
1WNL
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BU of 1wnl by Molmil
Crystal Structure Of Biotin-(Acetyl-CoA-Carboxylase) ligase From Pyrococcus Horikoshii Ot3 in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, biotin--[acetyl-CoA-carboxylase] ligase
Authors:Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-08-05
Release date:2005-08-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structures of Biotin Protein Ligase from Pyrococcus horikoshii OT3 and its Complexes: Structural Basis of Biotin Activation
J.Mol.Biol., 353, 2005
1WQW
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BU of 1wqw by Molmil
Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii Ot3 in complex with Biotinyl-5-AMP
Descriptor: BIOTINYL-5-AMP, biotin--[acetyl-CoA-carboxylase] ligase
Authors:Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-10-04
Release date:2005-10-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal Structures of Biotin Protein Ligase from Pyrococcus horikoshii OT3 and its Complexes: Structural Basis of Biotin Activation
J.Mol.Biol., 353, 2005
4XM6
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BU of 4xm6 by Molmil
Anthrax toxin lethal factor with ligand-induced binding pocket
Descriptor: 1,2-ETHANEDIOL, Lethal factor, N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-N~2~-(2-methylpropyl)-D-valinamide, ...
Authors:Maize, K.M, De la Mora-Rey, T, Finzel, B.C.
Deposit date:2015-01-14
Release date:2015-11-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.352 Å)
Cite:Ligand-induced expansion of the S1' site in the anthrax toxin lethal factor.
Febs Lett., 589, 2015

238582

数据于2025-07-09公开中

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