7U9K
Staphylococcus aureus D-alanine-D-alanine ligase in complex with ATP, D-ala-D-ala, Mg2+ and K+
Summary for 7U9K
| Entry DOI | 10.2210/pdb7u9k/pdb |
| Descriptor | D-alanine--D-alanine ligase, DAL-DAL, POTASSIUM ION, ... (7 entities in total) |
| Functional Keywords | atp-grasp, nucleotide binding, metal binding, ligase |
| Biological source | Staphylococcus aureus subsp. aureus NCTC 8325 More |
| Total number of polymer chains | 3 |
| Total formula weight | 83996.73 |
| Authors | Pederick, J.L.,Bruning, J.B. (deposition date: 2022-03-10, release date: 2023-03-15, Last modification date: 2024-01-31) |
| Primary citation | Becker, R.,Pederick, J.L.,Dawes, E.G.,Bruning, J.B.,Abell, A.D. Structure-guided design and synthesis of ATP-competitive N-acyl-substituted sulfamide d-alanine-d-alanine ligase inhibitors. Bioorg.Med.Chem., 96:117509-117509, 2023 Cited by PubMed: 37948922DOI: 10.1016/j.bmc.2023.117509 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report
