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4KG0
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BU of 4kg0 by Molmil
Crystal structure of the drosophila melanogaster neuralized-nhr1 domain
Descriptor: MAGNESIUM ION, Protein neuralized
Authors:Gupta, D, Ehebauer, M.T, Chirgadze, D.Y, Bolanos-Garcia, V.M, Blundell, T.L.
Deposit date:2013-04-28
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure, biochemical and biophysical characterisation of NHR1 domain of E3 Ubiquitin ligase neutralized
Advances in Enzyme Research, 1, 2013
7RL3
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BU of 7rl3 by Molmil
Structure of Drosophila melanogaster Plk4 PB3
Descriptor: Serine/threonine-protein kinase PLK4
Authors:Slep, K.C, Slevin, L.K.
Deposit date:2021-07-23
Release date:2022-08-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Polo-like kinase 4 homodimerization and condensate formation regulate its own protein levels but are not required for centriole assembly.
Mol.Biol.Cell, 34, 2023
5LSW
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BU of 5lsw by Molmil
A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell differentiation protein RCD1 homolog, LD12033p, ...
Authors:Sgromo, A, Raisch, T, Bawankar, P, Bhandari, D, Chen, Y, Kuzuoglu-Ozturk, D, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-09-05
Release date:2017-02-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin.
Nat Commun, 8, 2017
1FTZ
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BU of 1ftz by Molmil
NUCLEAR MAGNETIC RESONANCE SOLUTION STRUCTURE OF THE FUSHI TARAZU HOMEODOMAIN FROM DROSOPHILA AND COMPARISON WITH THE ANTENNAPEDIA HOMEODOMAIN
Descriptor: FUSHI TARAZU PROTEIN
Authors:Qian, Y.Q, Furukubo-Tokunaga, K, Resendez-Perez, D, Muller, M, Gehring, W.J, Wuthrich, K.
Deposit date:1994-01-07
Release date:1994-05-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance solution structure of the fushi tarazu homeodomain from Drosophila and comparison with the Antennapedia homeodomain.
J.Mol.Biol., 238, 1994
2NCD
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BU of 2ncd by Molmil
NCD (NON-CLARET DISJUNCTIONAL) DIMER FROM D. MELANOGASTER
Descriptor: ADENOSINE-5'-DIPHOSPHATE, PROTEIN (Kinesin motor NCD), SULFATE ION
Authors:Sablin, E.P, Case, R.B, Dai, S.C, Hart, C.L, Ruby, A, Vale, R.D, Fletterick, R.J.
Deposit date:1999-06-04
Release date:1999-06-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Direction determination in the minus-end-directed kinesin motor ncd.
Nature, 395, 1998
3KNF
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BU of 3knf by Molmil
Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum
Descriptor: D-tyrosyl-tRNA(Tyr) deacylase
Authors:Manickam, Y, Bhatt, T.K, Sharma, A.
Deposit date:2009-11-12
Release date:2009-12-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase
J.Biol.Chem., 285, 2010
6S9R
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BU of 6s9r by Molmil
Crystal structure of SSDP from D. melanogaster
Descriptor: Sequence-specific single-stranded DNA-binding protein, isoform A
Authors:Renko, M, Bienz, M.
Deposit date:2019-07-15
Release date:2019-10-09
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
3KO3
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BU of 3ko3 by Molmil
D-tyrosyl-tRNA(Tyr) deacylase from Plasmodium falciparum incomplex with ADP, obtained through soaking native enzyme crystal with the ATP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, D-tyrosyl-tRNA(Tyr) deacylase
Authors:Manickam, Y, Bhatt, T.K, Sharma, A.
Deposit date:2009-11-13
Release date:2009-12-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase
J.Biol.Chem., 285, 2010
3KOD
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BU of 3kod by Molmil
DTD from Plasmodium falciparum in complex with D-Serine
Descriptor: D-SERINE, D-tyrosyl-tRNA(Tyr) deacylase
Authors:Manickam, Y, Bhatt, T.K, Sharma, A.
Deposit date:2009-11-13
Release date:2009-12-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase
J.Biol.Chem., 285, 2010
3KO7
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BU of 3ko7 by Molmil
DTD from Plasmodium falciparum in complex with D-Lysine
Descriptor: D-LYSINE, D-tyrosyl-tRNA(Tyr) deacylase
Authors:Manickam, Y, Bhatt, T.K, Sharma, A.
Deposit date:2009-11-13
Release date:2009-12-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase
J.Biol.Chem., 285, 2010
3KO9
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BU of 3ko9 by Molmil
DTD from Plasmodium falciparum in complex with D-Arginine
Descriptor: D-ARGININE, D-tyrosyl-tRNA(Tyr) deacylase
Authors:Manickam, Y, Bhatt, T.K, Sharma, A.
Deposit date:2009-11-13
Release date:2009-12-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase
J.Biol.Chem., 285, 2010
8EW6
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BU of 8ew6 by Molmil
Anti-human CD8 VHH complex with CD8 alpha
Descriptor: Anti-CD8 alpha VHH, T-cell surface glycoprotein CD8 alpha chain
Authors:Kiefer, J.R, Williams, S, Davies, C.W, Koerber, J.T, Sriraman, S.K, Yin, Y.P.
Deposit date:2022-10-21
Release date:2022-11-23
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:Development of an 18 F-labeled anti-human CD8 VHH for same-day immunoPET imaging.
Eur J Nucl Med Mol Imaging, 50, 2023
3KO5
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BU of 3ko5 by Molmil
D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, D-tyrosyl-tRNA(Tyr) deacylase
Authors:Manickam, Y, Bhatt, T.K, Sharma, A.
Deposit date:2009-11-13
Release date:2009-12-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase
J.Biol.Chem., 285, 2010
5GKB
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BU of 5gkb by Molmil
Crystal Structure of Fatty Acid-Binding Protein in Brain Tissue of Drosophila melanogaster without citrate inside
Descriptor: Fatty acid bindin protein, isoform B
Authors:Cheng, Y.-Y, Huang, Y.-F, Lin, H.-H, Chang, W.W, Lyu, P.-C.
Deposit date:2016-07-04
Release date:2017-07-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:The ligand-mediated affinity of brain-type fatty acid-binding protein for membranes determines the directionality of lipophilic cargo transport.
Biochim Biophys Acta Mol Cell Biol Lipids, 1864, 2019
5GGE
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BU of 5gge by Molmil
Fatty Acid-Binding Protein in Brain Tissue of Drosophila melanogaster
Descriptor: CITRIC ACID, Fatty acid bindin protein, isoform B
Authors:Cheng, Y.-Y, Huang, Y.-F, Lin, H.-H, Chang, W.W, Lyu, P.-C.
Deposit date:2016-06-15
Release date:2017-06-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.861 Å)
Cite:The ligand-mediated affinity of brain-type fatty acid-binding protein for membranes determines the directionality of lipophilic cargo transport.
Biochim Biophys Acta Mol Cell Biol Lipids, 1864, 2019
8EDU
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BU of 8edu by Molmil
Mycobacteriophage Muddy capsid
Descriptor: Capsid
Authors:Freeman, K.G, White, S.J, Huet, A, Conway, J.F.
Deposit date:2022-09-06
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability.
Structure, 31, 2023
3LRS
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BU of 3lrs by Molmil
Structure of PG16, an antibody with broad and potent neutralization of HIV-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PG-16 Heavy Chain Fab, PG-16 Light Chain Fab
Authors:Pancera, M, Kwong, P.D.
Deposit date:2010-02-11
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1.
J.Virol., 84, 2010
8EEC
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BU of 8eec by Molmil
Crystal structure of HPK1 citron-homology domain
Descriptor: Isoform 2 of Mitogen-activated protein kinase kinase kinase kinase 1, PHOSPHATE ION
Authors:Wu, P, Lehoux, I, Wang, W.
Deposit date:2022-09-06
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:HPK1 Citron Homology Domain Serves as a Scaffold to Promote Phosphorylation of SLP76
To Be Published
4NV0
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BU of 4nv0 by Molmil
Crystal structure of cytosolic 5'-nucleotidase IIIB (cN-IIIB) bound to 7-methylguanosine
Descriptor: 7-METHYLGUANOSINE, 7-methylguanosine phosphate-specific 5'-nucleotidase, MAGNESIUM ION, ...
Authors:Monecke, T, Neumann, P, Ficner, R.
Deposit date:2013-12-04
Release date:2014-03-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structures of the Novel Cytosolic 5'-Nucleotidase IIIB Explain Its Preference for m7GMP
Plos One, 9, 2014
8G0L
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BU of 8g0l by Molmil
Semi-synthetic CoA-alpha-Synuclein Constructs Trap N-terminal Acetyltransferase NatB for Binding Mechanism Studies
Descriptor: Alpha-synuclein, CARBOXYMETHYL COENZYME *A, N-alpha-acetyltransferase 20, ...
Authors:Gardner, S.M, Marmorstein, R.
Deposit date:2023-01-31
Release date:2023-05-03
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Semi-synthetic CoA-alpha-Synuclein Constructs Trap N-terminal Acetyltransferase NatB for Binding Mechanism Studies.
Biorxiv, 2023
8FG8
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BU of 8fg8 by Molmil
Catalytic domain of GtfB in complex with inhibitor 2-[(2,4,5-Trihydroxyphenyl)methylidene]-1-benzofuran-3-one
Descriptor: (2Z)-2-[(2,4,5-trihydroxyphenyl)methylidene]-1-benzofuran-3(2H)-one, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
Authors:Schormann, N, Deivanayagam, C, Velu, S.
Deposit date:2022-12-12
Release date:2023-06-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Hydrogel-Encapsulated Biofilm Inhibitors Abrogate the Cariogenic Activity of Streptococcus mutans .
J.Med.Chem., 66, 2023
3MFK
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BU of 3mfk by Molmil
Ets1 complex with stromelysin-1 promoter DNA
Descriptor: Protein C-ets-1, stromelysin-1 promoter DNA
Authors:Babayeva, N.D, Mino, K, Tahirov, T.H.
Deposit date:2010-04-02
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of Ets1 cooperative binding to palindromic sequences on stromelysin-1 promoter DNA.
Cell Cycle, 9, 2010
3MF5
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BU of 3mf5 by Molmil
Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor
Descriptor: 3-[2-(trans-4-methylcyclohexyl)phenyl]-5-phenylthiophene-2-carboxylic acid, GLYCEROL, RNA-directed RNA polymerase
Authors:Harris, S.F, Tavares, G, Ghate, M.
Deposit date:2010-04-01
Release date:2010-07-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
7VKK
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BU of 7vkk by Molmil
Crystal structure of D. melanogaster SAMTOR V66W/E67P mutant
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-adenosylmethionine sensor upstream of mTORC1, SULFATE ION
Authors:Zhang, T, Ding, J.
Deposit date:2021-09-30
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022
7VKR
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BU of 7vkr by Molmil
Crystal structure of D. melanogaster SAMTOR in complex with SAM
Descriptor: CITRIC ACID, S-ADENOSYLMETHIONINE, S-adenosylmethionine sensor upstream of mTORC1
Authors:Tang, X, Zhang, T, Ding, J.
Deposit date:2021-09-30
Release date:2022-07-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022

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数据于2024-09-18公开中

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