PDB: 45817 resultsInfo pagesStatus searchChemie searchBIRD

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4FLV	Pyrococcus abyssi B family DNA polymerase bound to a dsDNA, in edition mode Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA polymerase 1, GLYCEROL, ... Authors: Gouge, J, Delarue, M. Deposit date: 2012-06-15 Release date: 2012-08-29 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase. J.Mol.Biol., 423, 2012
4FLX	Pyrococcus abyssi B family DNA polymerase bound to a dsDNA, in edition mode Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA polymerase 1, GLYCEROL, ... Authors: Gouge, J, Delarue, M. Deposit date: 2012-06-15 Release date: 2012-08-29 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase. J.Mol.Biol., 423, 2012
6BS1	Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Cisplatin, DNA (5'-D(*TP*AP*CP*TP*GP*GP*TP*AP*TP*GP*TP*AP*T)-3'), ... Authors: Jha, V.K, Ling, H. Deposit date: 2017-12-01 Release date: 2018-08-22 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender. J. Mol. Biol., 430, 2018
5N6I	Crystal structure of mouse cGAS in complex with 39 bp DNA Descriptor: Cyclic GMP-AMP synthase, DNA (36-MER), DNA (37-MER), ... Authors: Andreeva, L, Kostrewa, D, Hopfner, K.-P. Deposit date: 2017-02-15 Release date: 2017-09-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.6 Å) Cite: cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders. Nature, 549, 2017
6QY3	Segment of the Cas1-Cas2-Csn2-DNA filament complex from the Type II-A CRISPR-Cas system Descriptor: CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... Authors: Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. Deposit date: 2019-03-08 Release date: 2019-05-08 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (9.1 Å) Cite: Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75, 2019
6OE7	Crystal structure of HMCES cross-linked to DNA abasic site Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*GP*AP*CP*GP*TP*(DRZ)P*GP*TP*T)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*G)-3'), ... Authors: Halabelian, L, Li, Y, Zeng, H, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) Deposit date: 2019-03-27 Release date: 2019-04-24 Last modified: 2019-07-17 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition. Nat.Struct.Mol.Biol., 26, 2019
6WGF	Atomic model of mutant Mcm2-7 hexamer with Mcm6 WHD truncation Descriptor: DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ... Authors: Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. Deposit date: 2020-04-05 Release date: 2020-07-15 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (7.7 Å) Cite: Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
7P8L	Crystal structure of Pyrococcus abyssi 8-oxoguanine DNA glycosylase (PabAGOG) in complex with dsDNA containing cytosine opposite to 8-oxoG Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*(8OG)P*TP*TP*TP*CP*T)-3'), ... Authors: Coste, F, Flament, D, Castaing, B. Deposit date: 2021-07-23 Release date: 2022-08-03 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
6BRX	Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Cisplatin, DI(HYDROXYETHYL)ETHER, ... Authors: Jha, V.K, Ling, H. Deposit date: 2017-12-01 Release date: 2018-08-22 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender. J. Mol. Biol., 430, 2018
4FLU	Pyrococcus abyssi B family DNA polymerase bound to a dsDNA, in edition mode Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, MAGNESIUM ION, ... Authors: Gouge, J, Delarue, M. Deposit date: 2012-06-15 Release date: 2012-08-29 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase. J.Mol.Biol., 423, 2012
5E41	Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 5-(N-(10-hydroxydecanoyl)-aminopentenyl)-2'-deoxyuridine-triphosphate Descriptor: 2'-deoxy-5-{(1E)-5-[(10-hydroxydecanoyl)amino]pent-1-en-1-yl}uridine 5'-(tetrahydrogen triphosphate), DNA (5'-D(*AP*AP*AP*AP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... Authors: Hottin, A, Betz, K, Marx, A. Deposit date: 2015-10-05 Release date: 2016-12-07 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides. Chemistry, 23, 2017
6CST	Structure of human DNA polymerase kappa with DNA Descriptor: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, CHLORIDE ION, ... Authors: Jha, V, Ling, H. Deposit date: 2018-03-21 Release date: 2019-01-30 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2 Å) Cite: 2.0 angstrom resolution crystal structure of human pol kappa reveals a new catalytic function of N-clasp in DNA replication. Sci Rep, 8, 2018
3NCI	RB69 DNA Polymerase Ternary Complex with dCTP Opposite dG at 1.8 angstrom resolution Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... Authors: Wang, M, Blaha, G, Steitz, T.A, Konigsberg, W.H, Wang, J. Deposit date: 2010-06-04 Release date: 2011-02-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Insights into base selectivity from the 1.8 A resolution structure of an RB69 DNA polymerase ternary complex. Biochemistry, 50, 2011
3BJY	Catalytic core of Rev1 in complex with DNA (modified template guanine) and incoming nucleotide Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*DAP*DTP*DCP*DCP*DTP*DCP*DCP*DCP*DCP*DTP*DAP*(DOC))-3'), DNA (5'-D(*DTP*DAP*DAP*(P)P*DGP*DTP*DAP*DGP*DGP*DGP*DGP*DAP*DGP*DGP*DAP*DT)-3'), ... Authors: Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. Deposit date: 2007-12-05 Release date: 2008-10-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase Structure, 16, 2008
1TK8	T7 DNA polymerase ternary complex with 8 oxo guanosine and dAMP at the elongation site Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*AP*(8OG)P*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', ... Authors: Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. Deposit date: 2004-06-08 Release date: 2004-08-31 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004
1TK5	T7 DNA polymerase binary complex with 8 oxo guanosine in the templating strand Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*A*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DDG)P*TP*GP*CP*AP*A)-3', ... Authors: Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. Deposit date: 2004-06-08 Release date: 2004-08-31 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004
1TK0	T7 DNA polymerase ternary complex with 8 oxo guanosine and ddCTP at the insertion site Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', ... Authors: Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. Deposit date: 2004-06-07 Release date: 2004-08-31 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004
2G1P	Structure of E. coli DNA adenine methyltransferase (DAM) Descriptor: 5'-D(*TP*CP*TP*AP*GP*AP*TP*CP*TP*AP*GP*A)-3', DNA adenine methylase, GLYCEROL, ... Authors: Horton, J.R, Liebert, K, Bekes, M, Jeltsch, A, Cheng, X. Deposit date: 2006-02-14 Release date: 2006-11-21 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase. J.Mol.Biol., 358, 2006
3NAE	RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... Authors: Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. Deposit date: 2010-06-01 Release date: 2010-09-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.003 Å) Cite: Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin . Biochemistry, 49, 2010
1T8E	T7 DNA Polymerase Ternary Complex with dCTP at the Insertion Site. Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 25-MER, ... Authors: Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. Deposit date: 2004-05-12 Release date: 2004-10-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004
1TKD	T7 DNA polymerase ternary complex with 8 oxo guanosine and dCMP at the elongation site Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*CP*CP*CP*AP*(8OG)P*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3'), ... Authors: Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. Deposit date: 2004-06-08 Release date: 2004-08-31 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004
4QW8	TERNARY CRYSTAL STRUCTURES of A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH DNA AND D-DCTP Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*CP*AP*GP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3'), ... Authors: Gaur, V, Suo, Z. Deposit date: 2014-07-16 Release date: 2014-08-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymerase. Nucleic Acids Res., 42, 2014
4QWA	TERNARY CRYSTAL STRUCTURES OF A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS in COMPLEX WITH DNA AND (-)3TC-DP Descriptor: CALCIUM ION, DNA (5'-D(P*CP*AP*GP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3'), DNA (5'-D(P*GP*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*C)-3'), ... Authors: Gaur, V, Suo, Z. Deposit date: 2014-07-16 Release date: 2014-08-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymerase. Nucleic Acids Res., 42, 2014
6IPG	Post-catalytic Complex of Human DNA Polymerase Mu with Templating Cytosine and Mg-8oxodGMP Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*CP*TP*AP*CP*G)-3'), ... Authors: Chang, Y.K, Wu, W.J, Tsai, M.D. Deposit date: 2018-11-03 Release date: 2019-05-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
6IPD	Post-catalytic Complex of Human DNA Polymerase Mu with Templating Adenine and Mn-8oxodGMP Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ... Authors: Chang, Y.K, Wu, W.J, Tsai, M.D. Deposit date: 2018-11-03 Release date: 2019-05-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019

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